Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 (Q22252321)

6

object named as

Frederic Bibollet-Ruche

Frederic

Bibollet-Ruche

1 reference

7 February 2023

Mario L. Santiago

5

Mario L

Santiago

1 reference

7 February 2023

Paul M. Sharp

15

Paul M

Sharp

1 reference

7 February 2023

Pierre Roques

12

Pierre

Roques

1 reference

7 February 2023

Frank Kirchhoff

17

Frank

Kirchhoff

1 reference

7 February 2023

9

Martine Peeters

Martine

Peeters

1 reference

7 February 2023

3

Olaf Kutsch

Olaf

Kutsch

1 reference

7 February 2023

11

Elizabeth Bailes

Elizabeth

Bailes

1 reference

7 February 2023

14

Guido Silvestri

Guido

Silvestri

1 reference

7 February 2023

16

Beatrice H. Hahn

Beatrice H

Hahn

1 reference

7 February 2023

Michael Schindler

1

Michael

Schindler

1 reference

7 February 2023

Jan Münch

2

Jan

Münch

1 reference

7 February 2023

Hui Li

4

Hui

Li

1 reference

7 February 2023

Michaela C. Müller-Trutwin

7

Michaela C

Müller-Trutwin

1 reference

7 February 2023

Francis J. Novembre

8

Francis J

Novembre

1 reference

7 February 2023

Valerie Courgnaud

10

Valerie

Courgnaud

1 reference

7 February 2023

Donald L. Sodora

13

Donald L

Sodora

1 reference

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

7 February 2023

language of work or name

English

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publication date

June 2006

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published in

Cell

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volume

125

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issue

6

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page(s)

1055-1067

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cites work

1 reference

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7 January 2021

Identification of a nef allele that causes lymphocyte activation and acute disease in Macaque monkeys

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7 January 2021

Widely varying SIV prevalence rates in naturally infected primate species from Cameroon

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T cell stimulation and expansion using anti-CD3/CD28 beads

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7 January 2021

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

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7 January 2021

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

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7 January 2021

Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

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7 January 2021

HIV disease: fallout from a mucosal catastrophe?

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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

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7 January 2021

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

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7 January 2021

Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction

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7 January 2021

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

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7 January 2021

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

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7 January 2021

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

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7 January 2021

Reduced immune activation and T cell apoptosis in human immunodeficiency virus type 2 compared with type 1: correlation of T cell apoptosis with beta2 microglobulin concentration and disease evolution

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7 January 2021

Clinical, hematologic, and immunologic cross-sectional evaluation of individuals exposed to human immunodeficiency virus type-2 (HIV-2).

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7 January 2021

MRBAYES: Bayesian inference of phylogenetic trees

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7 January 2021

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

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7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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7 January 2021

Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR down-modulation

1 reference

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7 January 2021

HIV and SIV Nef modulate signal transduction and protein sorting in T cells

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7 January 2021

Naturally SIV-infected sooty mangabeys: are we closer to understanding why they do not develop AIDS?

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7 January 2021

Hybrid origin of SIV in chimpanzees.

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7 January 2021

Chimpanzee reservoirs of pandemic and nonpandemic HIV-1

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7 January 2021

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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7 January 2021

AIDS as a zoonosis: scientific and public health implications

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7 January 2021

Isolation of T-cell tropic HTLV-III-like retrovirus from macaques

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7 January 2021

The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo.

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7 January 2021

T-cell receptor:CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques

1 reference

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7 January 2021

Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

1 reference

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7 January 2021

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors

1 reference

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7 January 2021

New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): evidence for a cercopithecus monkey virus clade

1 reference

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7 January 2021

Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.

1 reference

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7 January 2021

Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.

1 reference

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7 January 2021

Simian Immunodeficiency Virus Infection of Chimpanzees

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7 January 2021

Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism

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7 January 2021

Viral persistence: HIV's strategies of immune system evasion

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7 January 2021

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

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7 January 2021

In vivo analysis of Nef function

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7 January 2021

Interactions of HIV-1 NEF with cellular signal transducing proteins

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7 January 2021

CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

1 reference

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7 January 2021

Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement

1 reference

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7 January 2021