POU domain, class 4, transcription factor 2 (Q21986679)

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mammalian protein found in Mus musculus
  • brain-specific homeobox/POU domain protein 3B
  • Brn-3B
  • brain-3B
  • Pou4f2
  • Brn-3.2
  • POU domain, class 4, transcription factor, related sequence 1
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Language Label Description Also known as
English
POU domain, class 4, transcription factor 2
mammalian protein found in Mus musculus
  • brain-specific homeobox/POU domain protein 3B
  • Brn-3B
  • brain-3B
  • Pou4f2
  • Brn-3.2
  • POU domain, class 4, transcription factor, related sequence 1

Statements

molecular function
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method or standard
IDA
IEA
ISO
8 references
retrieved
5 June 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
ISO
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IEA
retrieved
5 June 2018
stated in
Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IEA
retrieved
14 February 2019
stated in
Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
sequence-specific DNA binding
determination method or standard
IDA
IEA
IMP
6 references
retrieved
5 June 2018
stated in
Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IMP
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IEA
retrieved
5 June 2018
stated in
Brn3 transcription factors control terminal osteoclastogenesis
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
5 June 2018
stated in
Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
5 June 2018
stated in
The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
5 June 2018
stated in
Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63934&geneProductId=UniProtKB:Q63934
determination method or standard
IDA
cell component
nucleus
determination method or standard
IDA
IEA
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IEA
retrieved
14 February 2019
stated in
Brn3 transcription factors control terminal osteoclastogenesis
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
The Wilms' tumor suppressor Wt1 encodes a transcriptional activator of the class IV POU-domain factor Pou4f2 (Brn-3b)
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
biological process
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IEA
IGI
IMP
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
ISO
retrieved
14 February 2019
stated in
Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IMP
retrieved
14 February 2019
stated in
Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IMP
retrieved
14 February 2019
stated in
ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IEA
retrieved
14 February 2019
stated in
Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression
GOA
curator
UniProt
UniProt protein ID
Q63934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA
retrieved
14 February 2019
stated in
Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63934
determination method or standard
IDA

Identifiers

 
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