Myocyte enhancer factor 2D (Q21985115)

MADS MEF2-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

Holliday junction regulator protein family C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transcription factor, MADS-box, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

14 February 2019

Characterization of a cardiac-specific enhancer, which directs {alpha}-cardiac actin gene transcription in the mouse adult heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

RNA polymerase II transcription regulatory region sequence-specific DNA binding

protein dimerization activity

ISO

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

1 reference

14 February 2019

protein homodimerization activity

1 reference

14 February 2019

Regulation of the MEF2 family of transcription factors by p38

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

DNA-binding transcription factor activity

1 reference

14 February 2019

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

DNA-binding transcription activator activity, RNA polymerase II-specific

histone deacetylase binding

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

24 April 2018

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

24 April 2018

Regulatory role of MEF2D in serum induction of the c-jun promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

protein heterodimerization activity

1 reference

14 February 2019

Regulation of the MEF2 family of transcription factors by p38

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

enzyme binding

1 reference

14 February 2019

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

protein binding

1 reference

14 February 2019

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA-binding transcription activator activity, RNA polymerase II-specific

Regulatory role of MEF2D in serum induction of the c-jun promoter

4 references

11 October 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

11 October 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

1 January 2018

Regulatory role of MEF2D in serum induction of the c-jun promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

11 October 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

histone deacetylase binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

cell component

cytoplasm

1 reference

14 February 2019

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

nucleus

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Characterization of a cardiac-specific enhancer, which directs {alpha}-cardiac actin gene transcription in the mouse adult heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

IC

biological process

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

1 reference

14 February 2019

regulation of transcription, DNA-templated

chondrocyte differentiation

1 reference

14 February 2019

MEF2C transcription factor controls chondrocyte hypertrophy and bone development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

adult heart development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

endochondral ossification

1 reference

14 February 2019

MEF2C transcription factor controls chondrocyte hypertrophy and bone development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

1 reference

24 April 2018

nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

1 reference

14 February 2019

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

1 reference

14 February 2019

osteoblast differentiation

1 reference

14 February 2019

MEF2C transcription factor controls chondrocyte hypertrophy and bone development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

skeletal muscle cell differentiation

IMP

1 reference

14 February 2019

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

positive regulation of transcription by RNA polymerase II

IMP

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

ISO

14 February 2019

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Regulatory role of MEF2D in serum induction of the c-jun promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

14 February 2019

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

1 reference

14 February 2019

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63943&geneProductId=UniProtKB:Q63943

regulation of transcription, DNA-templated

1 reference

14 February 2019

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63943

Holliday junction regulator protein family C-terminal

has part(s)

1 reference

Transcription factor, MADS-box

1 reference

MADS MEF2-like

1 reference