Regulator of G-protein signaling 14 (Q21980136)

Ubiquitin-like domain superfamily

1 reference

RGS domain superfamily

1 reference

RGS, subdomain 1/3

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

RGS14, RGS domain, protein family

1 reference

regulator of G protein signalling

1 reference

Raf-like Ras-binding domain, protein family

1 reference

GoLoco motif domain, protein family

1 reference

GTPase activating protein binding

1 reference

25 May 2022

1 reference

25 May 2022

GTPase activator activity

IPI

A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

GTPase regulator activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

microtubule binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

protein binding

IPI

1 reference

8 April 2019

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

GDP-dissociation inhibitor activity

IPI

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

G-protein alpha-subunit binding

signaling receptor complex adaptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

postsynaptic membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

nuclear body

1 reference

8 April 2019

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

postsynaptic density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

3 references

8 April 2019

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

spindle

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a microtubule-associated protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

microtubule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

spindle pole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

nucleus

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

cytoplasm

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

centrosome

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

plasma membrane

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

dendrite

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

glutamatergic synapse

Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

G protein-coupled receptor signaling pathway

biological process

TAS

1 reference

8 April 2019

A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

intracellular signal transduction

TAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

chromosome segregation

1 reference

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

learning

1 reference

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

spindle organization

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

long-term memory

1 reference

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

negative regulation of MAP kinase activity

1 reference

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

zygote asymmetric cell division

1 reference

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

negative regulation of signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

regulation of DNA-templated transcription in response to stress

1 reference

8 April 2019

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

negative regulation of synaptic plasticity

1 reference

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

1 reference

8 April 2019

long-term potentiation

1 reference

8 April 2019

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

mitotic cell cycle

1 reference

8 April 2019

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

nucleocytoplasmic transport

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

response to oxidative stress

regulation of G protein-coupled receptor signaling pathway

visual learning

positive regulation of GTPase activity

1 reference

8 April 2019

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

negative regulation of G protein-coupled receptor signaling pathway

1 reference

8 April 2019

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

platelet-derived growth factor receptor signaling pathway

positive regulation of neurogenesis

negative regulation of ERK1 and ERK2 cascade

modulation of chemical synaptic transmission

Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

8 April 2019

Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492

positive regulation of signal transduction

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97492