LARGE xylosyl- and glucuronyltransferase 1 (Q21494710)

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mammalian protein found in Mus musculus

acetylglucosaminyltransferase-like 1A
xylosyl- and glucuronyltransferase LARGE1
glycosyltransferase-like protein LARGE1
myodystrophy
like-glycosyltransferase
Large1

Language	Label	Description	Also known as
English	LARGE xylosyl- and glucuronyltransferase 1	mammalian protein found in Mus musculus	acetylglucosaminyltransferase-like 1A xylosyl- and glucuronyltransferase LARGE1 glycosyltransferase-like protein LARGE1 myodystrophy like-glycosyltransferase Large1

Statements

1 reference

25 May 2022

UniProt protein ID

nucleotide-diphospho-sugar transferases

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1M7

Glycosyl transferase, family 8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1M7

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

metal ion binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

transferase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

catalytic activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

protein binding

determination method or standard

1 reference

14 February 2019

Molecular recognition by LARGE is essential for expression of functional dystroglycan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

glycosyltransferase activity

determination method or standard

4 references

11 October 2018

Glycosylation defects: a new mechanism for muscular dystrophy?

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

glucuronosyltransferase activity

determination method or standard

5 references

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

manganese ion binding

determination method or standard

xylosyltransferase activity

determination method or standard

5 references

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

glucuronosyltransferase activity

determination method or standard

6 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

glycosyltransferase activity

determination method or standard

5 references

14 February 2019

Glycosylation defects: a new mechanism for muscular dystrophy?

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

xylosyltransferase activity

determination method or standard

6 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

integral component of membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

intracellular membrane-bounded organelle

determination method or standard

1 reference

14 February 2019

Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

Golgi apparatus

determination method or standard

4 references

11 October 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

Golgi apparatus

determination method or standard

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

biological process

skeletal muscle organ development

determination method or standard

1 reference

14 February 2019

LARGE glycans on dystroglycan function as a tunable matrix scaffold to prevent dystrophy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

muscle cell cellular homeostasis

determination method or standard

1 reference

14 February 2019

Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

skeletal muscle tissue regeneration

determination method or standard

1 reference

14 February 2019

LARGE glycans on dystroglycan function as a tunable matrix scaffold to prevent dystrophy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

glycoprotein biosynthetic process

determination method or standard

1 reference

14 February 2019

Glycosylation defects: a new mechanism for muscular dystrophy?

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

protein glycosylation

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

protein O-linked mannosylation

determination method or standard

4 references

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

11 October 2018

LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1M7&geneProductId=UniProtKB:Q9Z1M7

determination method or standard

protein O-linked mannosylation

determination method or standard

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1M7

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000004497

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000004497

ENSMUSP00000112617

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000112617

ENSMUSP00000148336

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000148336

Sitelinks

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