Adenosine deaminase, RNA specific (Q21118028)

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mammalian protein found in Homo sapiens
  • IFI-4
  • interferon-inducible protein 4
  • p136
  • ADAR
  • 136 kDa double-stranded RNA-binding protein
  • adenosine deaminase acting on RNA 1-A
  • double-stranded RNA-specific adenosine deaminase
  • dsRNA adenosine deaminase
  • K88DSRBP
  • interferon-induced protein 4
  • dsRNA adeonosine deaminase
edit
Language Label Description Also known as
English
Adenosine deaminase, RNA specific
mammalian protein found in Homo sapiens
  • IFI-4
  • interferon-inducible protein 4
  • p136
  • ADAR
  • 136 kDa double-stranded RNA-binding protein
  • adenosine deaminase acting on RNA 1-A
  • double-stranded RNA-specific adenosine deaminase
  • dsRNA adenosine deaminase
  • K88DSRBP
  • interferon-induced protein 4
  • dsRNA adeonosine deaminase

Statements

molecular function
double-stranded RNA adenosine deaminase activity
determination method or standard
NAS
IDA
IEA
TAS
6 references
retrieved
24 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
24 October 2017
stated in
Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
24 October 2017
stated in
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
NAS
retrieved
24 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
protein binding
determination method or standard
IPI
6 references
retrieved
8 April 2019
stated in
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IPI
retrieved
8 April 2019
stated in
The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IPI
retrieved
8 April 2019
stated in
The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification and comparative analysis of hepatitis C virus-host cell protein interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IPI
retrieved
8 April 2019
stated in
Viral immune modulators perturb the human molecular network by common and unique strategies
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IPI
retrieved
8 April 2019
stated in
The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IPI
double-stranded RNA adenosine deaminase activity
determination method or standard
IBA
IDA
IEA
NAS
TAS
5 references
retrieved
8 April 2019
stated in
Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
8 April 2019
stated in
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
NAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
8 April 2019
stated in
Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IBA
cell component
cytoplasm
determination method or standard
IDA
TAS
IEA
6 references
retrieved
24 October 2017
stated in
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
24 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
nucleus
determination method or standard
IDA
TAS
IEA
9 references
retrieved
24 October 2017
stated in
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
24 October 2017
stated in
Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
24 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
TAS
8 references
retrieved
8 April 2019
stated in
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
8 April 2019
stated in
Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
8 April 2019
stated in
The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IBA
biological process
adenosine to inosine editing
determination method or standard
IDA
TAS
IMP
IEA
6 references
retrieved
24 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
24 October 2017
stated in
The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IMP
retrieved
24 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
24 October 2017
stated in
New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
24 October 2017
stated in
Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55265&geneProductId=UniProtKB:P55265
determination method or standard
IDA
adenosine to inosine editing
determination method or standard
IBA
IDA
IMP
TAS
6 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
1 January 2018
stated in
The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IMP
retrieved
1 January 2018
stated in
ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
1 January 2018
stated in
Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
1 January 2018
stated in
New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IBA
adenosine to inosine editing
determination method or standard
IBA
IDA
IEA
IMP
TAS
7 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
TAS
retrieved
8 April 2019
stated in
The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IEA
retrieved
8 April 2019
stated in
Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor
GOA
curator
UniProt
UniProt protein ID
P55265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55265
determination method or standard
IBA

Identifiers

Freebase ID
/m/03gvl48
0 references
 
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