ELAV like RNA binding protein 1 (Q21113266)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
HuR
ELAVL1
ELAV-like protein 1
embryonic lethal, abnormal vision, drosophila, homolog-like 1
hu-antigen R
Hu antigen R

Language	Label	Description	Also known as
English	ELAV like RNA binding protein 1	mammalian protein found in Homo sapiens	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) HuR ELAVL1 ELAV-like protein 1 embryonic lethal, abnormal vision, drosophila, homolog-like 1 hu-antigen R Hu antigen R

Statements

1 reference

13 November 2019

UniProt protein ID

Splicing factor ELAV/Hu

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15717

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15717

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15717

HuR, RNA recognition motif 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

Splicing factor ELAV/Hu, RNA recognition motif 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA recognition motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein homodimerization activity

determination method or standard

1 reference

8 April 2019

Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

protein binding

determination method or standard

8 references

8 April 2019

Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ubiquitin-mediated proteolysis of HuR by heat shock

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

6 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

26 September 2017

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

26 September 2017

Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

nucleic acid binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

double-stranded RNA binding

determination method or standard

1 reference

8 April 2019

Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

protein kinase binding

determination method or standard

mRNA 3'-UTR AU-rich region binding

determination method or standard

6 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Angiogenesis inhibitor vasohibin-1 enhances stress resistance of endothelial cells via induction of SOD2 and SIRT1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

6 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

mRNA 3'-UTR binding

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

1 reference

8 April 2019

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

1 reference

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

cytoplasmic stress granule

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

glutamatergic synapse

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

biological process

regulation of mRNA stability

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

multicellular organism development

determination method or standard

1 reference

1 January 2018

Localization of the human HuR gene to chromosome 19p13.2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

mRNA stabilization

determination method or standard

3 references

8 April 2019

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

3'-UTR-mediated mRNA stabilization

determination method or standard

2 references

26 September 2017

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

26 September 2017

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

mRNA splicing, via spliceosome

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

negative regulation of gene silencing by miRNA

determination method or standard

1 reference

26 September 2017

Post-transcriptional regulation of Wnt co-receptor LRP6 and RNA-binding protein HuR by miR-29b in intestinal epithelial cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15717&geneProductId=UniProtKB:Q15717

determination method or standard

protein homooligomerization

determination method or standard

1 reference

8 April 2019

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

negative regulation of gene silencing by miRNA

determination method or standard

3'-UTR-mediated mRNA stabilization

determination method or standard

5 references

8 April 2019

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

8 April 2019

Role of N-myristoylation in stability and subcellular localization of the CLPABP protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15717

determination method or standard

RNA recognition motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15717

Splicing factor ELAV/Hu, RNA recognition motif 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15717

HuR, RNA recognition motif 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15717

Identifiers

MeSH descriptor ID

subject named as

ELAV-Like Protein 1

0 references

D12.776.157.725.813.500.250

0 references

D12.776.664.962.813.500.250

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000385269

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000385269

ENSP00000472197

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472197

ENSP00000470727

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470727

ENSP00000471011

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000471011

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21113266&oldid=2022953228"