LDL receptor related protein 5 (Q21111886)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75197

LDL receptor-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75197

Six-bladed beta-propeller, TolB-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75197

EGF-like domain, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A, conserved site, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A repeat, protein family

1 reference

LDLR class B repeat, protein family

1 reference

toxin transmembrane transporter activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Evidence against a human cell-specific role for LRP6 in anthrax toxin entry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

protein binding

8 references

8 April 2019

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

coreceptor activity involved in Wnt signaling pathway

1 reference

8 April 2019

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

Wnt-activated receptor activity

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75197&geneProductId=UniProtKB:O75197

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75197&geneProductId=UniProtKB:O75197

1 January 2018

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75197&geneProductId=UniProtKB:O75197

coreceptor activity involved in canonical Wnt signaling pathway

1 reference

8 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

Wnt-protein binding

The importance of Wnt signalling for neurodegeneration in Parkinson's disease

5 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

ISS

3 January 2017

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

Wnt-protein binding

The importance of Wnt signalling for neurodegeneration in Parkinson's disease

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

ISS

8 April 2019

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

Wnt-activated receptor activity

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

8 April 2019

LRP5 variants may contribute to ADPKD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

1 reference

8 April 2019

Wnt signalosome

1 reference

8 April 2019

The regulation and deregulation of Wnt signaling by PARK genes in health and disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

Wnt-Frizzled-LRP5/6 complex

TAS

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

1 reference

8 April 2019

receptor complex

1 reference

3 January 2017

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

1 reference

8 April 2019

mitochondrion

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

3 references

8 April 2019

TAS

8 April 2019

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

regulation of apoptotic process

biological process

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

positive regulation of osteoblast proliferation

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

1 reference

8 April 2019

limb morphogenesis

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

extracellular matrix-cell signaling

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

branching involved in mammary gland duct morphogenesis

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

somatic stem cell population maintenance

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

bone marrow development

1 reference

3 January 2017

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

regulation of canonical Wnt signaling pathway

1 reference

3 January 2017

An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

bone morphogenesis

3 references

3 January 2017

Low-density lipoprotein receptor-related protein 5 polymorphisms are associated with bone mineral density in Greek postmenopausal women: an interaction with calcium intake

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Association of LPR5 polymorphism with bone mass density and cholesterol level in population of Chinese Han

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

gastrulation with mouth forming second

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

embryonic digit morphogenesis

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

positive regulation of DNA-binding transcription factor activity

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

cell-cell signaling involved in mammary gland development

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

cholesterol metabolic process

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

Wnt signaling pathway

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

4 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Moderate reduction of Norrin signaling activity associated with the causative missense mutations identified in patients with familial exudative vitreoretinopathy

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

negative regulation of osteoblast differentiation

1 reference

8 April 2019

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

anatomical structure regression

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

mammary gland duct morphogenesis

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

regulation of blood pressure

1 reference

8 April 2019

LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

positive regulation of transcription, DNA-templated

3 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Moderate reduction of Norrin signaling activity associated with the causative missense mutations identified in patients with familial exudative vitreoretinopathy

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

1 reference

8 April 2019

retina morphogenesis in camera-type eye

1 reference

8 April 2019

Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

vasculature development

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

apoptotic process involved in blood vessel morphogenesis

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

positive regulation of mesenchymal cell proliferation

1 reference

8 April 2019

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

bone remodeling

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

Wnt signaling pathway involved in dorsal/ventral axis specification

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

glucose catabolic process

1 reference

8 April 2019

Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

positive regulation of cell population proliferation

1 reference

8 April 2019

Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

canonical Wnt signaling pathway

Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

6 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

3 January 2017

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

negative regulation of protein serine/threonine kinase activity

1 reference

8 April 2019

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

adipose tissue development

1 reference

3 January 2017

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

cell migration involved in gastrulation

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

bone development

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

positive regulation of fat cell differentiation

1 reference

8 April 2019

Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

positive regulation of mitotic nuclear division

1 reference

8 April 2019

Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

retina vasculature morphogenesis in camera-type eye

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

anterior/posterior pattern specification

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

positive regulation of transcription by RNA polymerase II

1 reference

3 January 2017

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

regulation of bone remodeling

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

beta-catenin destruction complex disassembly

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

1 reference

3 January 2017

response to peptide hormone

TAS

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O75197

gastrulation with mouth forming second

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

osteoblast development

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

anterior/posterior pattern specification

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

cholesterol homeostasis

LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Association of LPR5 polymorphism with bone mass density and cholesterol level in population of Chinese Han

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

positive regulation of osteoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

positive regulation of transcription, DNA-templated

ISS

2 references

8 April 2019

Moderate reduction of Norrin signaling activity associated with the causative missense mutations identified in patients with familial exudative vitreoretinopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

positive regulation of transcription by RNA polymerase II

bone remodeling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

bone marrow development

canonical Wnt signaling pathway

Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

12 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

IGI

8 April 2019

Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

8 April 2019

LRP5 variants may contribute to ADPKD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

bone morphogenesis

Low-density lipoprotein receptor-related protein 5 polymorphisms are associated with bone mineral density in Greek postmenopausal women: an interaction with calcium intake

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Association of LPR5 polymorphism with bone mass density and cholesterol level in population of Chinese Han

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

branching involved in mammary gland duct morphogenesis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

adipose tissue development

regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

retinal blood vessel morphogenesis

Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

toxin transport

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

1 reference

8 April 2019

Norrin signaling pathway

2 references

8 April 2019

Moderate reduction of Norrin signaling activity associated with the causative missense mutations identified in patients with familial exudative vitreoretinopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

8 April 2019

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75197

D12.776.543.750.710.450.500.400

Identifiers

MeSH descriptor ID

D060492

subject named as

Low Density Lipoprotein Receptor-Related Protein-5

0 references

MeSH tree code

D12.776.526.500

0 references

0 references

D12.776.543.750.850.687

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023