Anatomy and Physiology Lec and Lab 3

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Transport through

Cell Membranes
AILEEN MAE C. MIGALANG, RN
The Cell
• Eukaryotic Cell -have nucleus which contain the cell’s
DNA and has specialized structures called organelles.
• Ex: animal and plant cell

• Prokaryotic Cell- DNA isn’t encapsulated within a nucleus


and the organelles are missing.
• Ex: Bacteria and Archaea
Specialized Cells
• Neurons
• Enterocytes
• Pneumocytes
• Nephrons
• Erythrocytes
• Leukocytes
• Thrombocytes
• Melanocytes
Membrane Transport
• Movement of particles across or through plasma
membrane.
• Example of particles are water, carbon dioxide, oxygen,
ions, fatty acids and glucose.
Plasma Membrane
Two Major Types
• A. Passive Transport Mechanism
• B. Active Transport Mechanism
Passive Transport Mechanism
• A type of cellular transport in which substances move
down their respective concentration gradient not
requiring any amount of energy (ATP).
Osmosis
• Movement of water molecules from area of low
concentration to area of high concentration
Simple Diffusion
• The net passive movement of substances (solutes) from
greater concentration area to lower concentration area.
Simple diffusion does not require assistance of membrane
proteins to move substance downhill.
• Ex: oxygen and carbon dioxide
Facilitated Diffusion
• A passive transport of molecules across the plasma
membrane via protein membranes.
• Ex: glucose, ions
Active Transport Mechanism
• The movement of molecules across cell membrane in the
direction which is against the concentration gradient
thus, requiring energy.
• Ex. Pumps and protein carriers
Primary Active Transport
• A direct active transport, directly uses energy ATP to
move substances or solutes into the cell.
• Ex: Sodium-Potassium Pump
Secondary Active Transport
• Uses energy stored in set-up gradient to move other
substances against their own gradient.
• Ex:
• 1. Symport ( when transported and co-transported
molecule move in the same direction.)
• 2. Antiport (when they move in different directions.)
Symport
Antiport
Endocytosis
• A process of capturing a substance or particle from
outside the cell.
Exocytosis
• The process of vesicles fusing with the plasma membrane
and releasing the content to the outside of the cell.
TONICITY OF SOLUTION
• The ability of an extracellular solution to make water
move into and out of the cell by osmosis.
Isotonic
• There will be no net flow of water into or out of the cell.
• The cell’s volume will remain stable.
• The solute concentration outside the cell is the same as
inside the cell, and the solutes cannot cross the
membrane.
Hypotonic
• There will be a net flow of water into the cell.
• The cell will gain volume.
• If the solute concentration outside the cell is lower than
inside the cell, and the solutes cannot cross the
membrane.
Hypertonic
• There will be a net flow of water out of the cell.
• The cell will lose volume.
• A solution will be hypertonic to a cell if its solute
concentration is higher than that inside the cell, and the
solutes cannot cross the membrane.

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