Journal Club Headneck

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Marco Neri, MD

Journal club, April


24, 2019
Background
Drainage after routine thyroid and
parathyroid surgery remains
controversial
Increasing evidence from a number of
randomized clinical trials (RCTs)
suggesting no benefit from the use of
drains
The routine use of drains in many
surgical procedures is no longer
recommended
Background
Haematoma rates are low, with a
reported incidence of 0 – 2·6 per
cent and an even lower incidence
of 0 – 1·5 per cent for those
requiring intervention
Population
Inclusion criteria
 All published and unpublished RCTs in any language
comparing the use of any form of postoperative
drainage (open, passive or suction) versus no
drainage in patients of any age who underwent any
thyroid or parathyroid surgery, irrespective of
indication
Exclusion criteria
 Lateral neck dissections
 Extensive neck surgery large goiters
 Substernal goiters, thoracotomy
 Minimaly invasive surgeries, previous thyroid
surgeries
Outcomes
Rate of reoperation
Wound infection rate
Post operative pain
Length of hospital stay
Search strategy
Search terms ‘thyroid’ or ‘thyroidectomy’ or
‘Graves’ or ‘goitre’ or ‘parathyroid’ or
‘parathyroidectomy’ and ‘drain’ or
‘drainage’ or ‘surgery’
Databases searched:
Coch-rane Library and Central Register of
Controlled Trials (April 2013), MEDLINE
(January 1966 to April 2013), Embase
(January 1980 to April 2013) and Cumulative
Index to Nursing and Allied Health (CINAHL)
(January 1982 to April 2013)
Stastical analysis
 The software package RevMan 5.2 (Cochrane
Collaboration, Nordic Cochrane Centre,
Copenhagen, Denmark) was used to analyse
data. Risk ratios (RRs) and 95 percent
confidence intervals (c.i.) were used for
dichotomousvariables, and mean differences
(MDs) with 95 % c.i. for continuous data
Results
 Twenty-five trials reported on reoperation
rate, including a total of 2939 patients. The
rate of reoperation was low in both the drain
and no-drain groups. The need for
reoperation was no different between the
two groups.
Results
Wound infection rates were reported in
17 trials, including a total of 2035
patients. There was a higher wound
infection rate in the drain group.
Conclusion
This meta-analysis suggests
that it is safe not to use drains
following routine thyroid surgery
and that this practice may have
some benefits for the patient
Critical appraisal
 Are the results of the study valid?
 Did the study ask a clearly focused question?
 YES
 Was this an RCT and was it appropriately so?
 YES
 Were the participants appropriately allocated to
intervention and control groups?
 YES
Were the participants, staff, and study
personnel blind to participants’ study group?
NO
Were all of the participants who entered the
trial accounted for at its conclusion?
YES
Were the participants in all groups followed
up and data collected in the same way?
YES
Did the study have enough participants
to minimize the play of chance?
YES
 Were all important outcomes considered so the
results can be applied?
 YES
Thank you! :)

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