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    Sukhpreet Kaur Practice School

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    Sukhpreet Kaur Practice School

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    sukhpreetkauraroraa13
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    7 views22 pages

    Sukhpreet Kaur Practice School

    Uploaded by

    sukhpreetkauraroraa13

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 22

    Formulation and Characterisation of Vitamin C

    serum with Kojic Acid and Green Tea

    Submitted by: Sukhpreet Kaur Submitted to: Ms. Tamanna Sharma


    (2021249) Assistant professor
    B pharmacy 7th Sem

    Faculty Of Pharmaceutical Sciences


    PCTE Group of Institutes 1
    Table of Contents
    • Introduction - Anatomy of Skin
    • Skin Related Issues
    • Project Aim and Objectives
    • Literature Review
    • Formulation
    • Materials and Method
    • Novelty of the Product
    • Potential Uses
    • Project Timelines
    • Conclusion
    • References
    2
    Introduction
    Epidermis:
    ● outermost layer of skin
    ● provides skin colour, formation of
    new skin cells (via melanin)
    Dermis:
    ● middle layer
    ● regulates body temperature
    through sweat gland activity
    ● produces collagen

    3
    Hypodermis:

    • Innermost layer
    • Acts as a shock absorber for bones

    4
    • Serums are defined as concentrated product that contains ten times more organic matter than
    cream
    • Deals with the cosmetic problem quickly and effectively
    • Highly concentrated emulsion which is available in water based and oil based
    Skin Issues

    80% 39.5% 30-40%


    HYPERPIGMENTATION ACNE SCARS FINE LINES AND
    WRINKLES

    ● UNEVEN SKIN TONE ● POST ACNE MARKS ON ● REDUCED COLLAGEN


    ● DULL SKIN SKIN ● SAGGY SKIN
    ● DARK SPOTS
    Skin Issue Characteristics

    1. HYPERPIGMENTATION Darkening of skin areas due to increased melanin


    production, sun exposure, PIH, age

    2. FINE LINES Thin, shallow lines, appear with age infrequent


    moving areas of face like eyes
    WRINKLES Are more deep, forms when skin loses collagen and
    elasticity

    3. UNEVEN SKIN Variations in skin colour resulting in dark areas or


    patches
    Can be due to excessive sun exposure,PIH
    4. DULL SKIN TONE Skin lacks, radiance, less vibrant.
    can be due to dead skin cells, dehydration, etc
    Dark spots, Acne scars Hyperpigmentation

    Dull skin Fine lines and Wrinkles


    Project Aim and Objectives
    • To research about effective uses of Vitamin C face serum
    • To formulate Vitamin C face serum
    • To demolish various skin issues
    • To establish Anti-oxidant protection
    • To enhance collagen production
    • To overall enhance skin texture
    Literature Review
    Article title Author’s name Published year Aim to study

    Formulation and Dr. S.V Patil, May 2023 This study highlights the use of Chrysanthemum
    Evaluation Of Face Prajakta Patil, Riya Patil, and its benefits for skin. It highlights the properties
    Serum et.al. of glycerin, Vitamin C, E, A for skin health

    Facial Serum: It’s Tejal Shirish Shejul, Prof. March- April The study highlights the importance of skin health,
    Formulation, Usage, Kiran Kudale. 2023 serum benefits, and their skin - enhancing effects.
    Special Ingredients,
    Various types and
    Benefits
    Formulation and Evaluation Miss. Ashwini. R. Patil, April 2023 The paper highlights the importance of
    of Herbal Face Serum Miss. Anjali. R. Patil, usage of aloe vera in skincare serums and its
    Containig Aloe Vera and R. B. lovhare. benefits for skin health.
    Aegle Maemelos It’s anti-inflammatory and moisturising
    properties were discussed.

    Kojic Acid Applications in Majid Saeedi, Masoumeh February 2019 This paper discusses the inhibition
    Cosmetic and Pharmaceutical Eslamifar, et.al. properties of Kojic Acid and enhancement of
    Preparations Skin texture and overall pigment. It
    discusses its UV protecting properties

    Formulation and Evaluation Miss. Purva S Rajdev, Prof. June 2022 The study aimed to create a serum with quick
    of Face Serum Gaikwad S. D, et.al absorption and deep skin penetration, high in
    active ingredients, to combat skin aging
    from UV damage.
    Topical Vitamin C and The Firas Al-Niaimi, July 2017 This review article details the
    Skin: Mechanisms of Action Nicole Yi Zhen Chiang. main mechanisms of action and clinical
    and Applications applications of topical vitamin C on the skin,
    including its antioxidative, photoprotective,
    ant-iaging, and anti pigmentation effects.

    December
    Formulation of Herbal Face Neha Joshi, Roht Ade, et.al. This review highlights the formulation of a
    2022
    Serum Containing Aloe Vera herbal face serum with Aloe vera and Citric
    and Citric Acid Acid and its benefits for skin health.

    Formulation and Evaluation Khan Talha N, November The goal of this research was to
    of Herbal Face Serum Pawar Shankar, et.al. 2022 create a serum using
    polyherbal extract based on these qualities.
    Formulation

    Ingredients Working formula (30ml)

    Aloe vera 10g


    Glycerin 5ml
    Vitamin C 10%
    Kojic Acid 2%
    Green Tea Extract 0.5-1%
    Xanthin gum/ Lecithin 2%
    De- mineralized Water q.s.
    Materials and Method
    Ingredients uses
    Aloe vera ● Helps to moisturize the skin
    ● It anti-ageing properties
    ● It reduces skin infection
    ● Aloe vera also has high water content regular use
    of aloe vera in serum it can make skin radiant and
    youthful
    Glycerin ● Glycerin is a humectant
    ● A type of moisturizing agent that pulls water the
    outer layer of skin from deeper levels of the skin
    and the air
    ● It improve the skin barrier function
    Vitamin C ● supporting the synthesis of collagen, which is
    essential for connective tissue such as skin
    ● limiting the damaging effects of free radicals,
    which protect the skin from sun damage and aging
    ● providing additional protection from sun damage in
    combination with sunscreen
    ● reducing redness
    ● improve the appearance of wrinkles
    ● diminishing dark spots
    ● reducing acne

    Kojic Acid ● Inhibits the production of melanin in the skin


    ● Acts as an antioxidant
    ● Has anti-inflammatory and anti-viral properties

    Green Tea Extract ● Has both Vit E and Vit B


    ● Anti- inflammatory properties
    ● Anti- bacterial properties

    Xanthin gum/ Lecithin ● emulsifier


    De-mineralized water ● It included hydrating properties which are helpful
    for maintaining viscosity of serum.
    STEP 1 STEP 2 STEP 3 STEP 4 STEP 5

    The formulation was The oil phase was Both phases are A.vera extract and
    Aqueous phase was
    divided into two taken into a beaker homogenized green tea extract
    added slowly to the
    phases: oil phase and and homogenized perfectly for approx. were added and
    oily phase with
    aqueous phase for 15 min at 1000 20 min at 1000 rpm homogenized for 15
    constant stirring.
    rpm min at 1000 rpm to
    Emulsifying agent get the desired
    was added next. serum formulation
    Novelty of the Product

    The novelty in combining these ingredients is that they complement each other's actions and
    provide a comprehensive approach to skincare. Together, they offer a well-rounded solution for:

    ● Protecting the skin from environmental damage.


    ● Reducing hyperpigmentation and improving skin tone.
    ● Promoting collagen synthesis and minimizing the signs of aging.
    ● Providing anti-inflammatory and soothing effects.
    Potential Uses
    • Brightening skin tone
    • Anti-aging
    • Anti-oxidant protection
    • Evening of Skin Tone
    • Hydration and Skin health
    • Soothing and Anti-inflammatory
    • Added UV protection
    • Preventing further damage
    Project Timelines

    • Product selection – 25th august to 28th august


    • Literature review – 29th august – 5th September
    • Introduction of topic – 6th September to 8th September
    • Ingredient details and selection- 9 th September- 14th September
    • Formulation selection – 15th September to 20th September
    • Methodology- 21st September to 24th September
    • Report preparation – 25th September to 26th September
    Conclusion

    ❖ In summary, creating and analyzing a vitamin C serum enriched with kojic acid and green

    tea extract results in a versatile skincare product.

    ❖ This combination of active ingredients offers numerous advantages, including skin

    brightening, anti-aging effects, antioxidant protection, texture improvement, and soothing

    properties.

    ❖ In essence, this serum formulation represents a comprehensive approach to achieving

    healthier and more radiant skin.


    References
    • Optimization, stability and characterization of face serum formulation by Mumtaz BT Sultan
    Suhai Budden A
    • Indian Dermatology Online Journal Vitamin C in dermatology PumoriSaokarTelang; Indian
    Dermatology, Apr–Jun 2013 - Volume 4- Issue 2 - pp 143-146
    • Green tea and the skin from Journal of the American Academy of Dermatology; by Stephen
    Hsu
    • P. K. Sahu, D. D. Giri, R. singh, P. Pandey, S. Gupta, A. K. Shrivastava, Ajay Kumar, K. D.
    Pandey, “Therapeutic and Medicinal Uses of Aloe Vera: A Review”, Scientific Research-
    pharmacognosy and Pharmacy, 2013,4,599-610.
    • International research of Pharmaceutical Research and Application, Neha joshi, Rohit Ade,
    Gokul Gangurde, Bhagyashree.S.Suryawanshi, “Formulation of Herbal Face Serum
    Containing Aloe vera and Citric acid” December 2022, pp - 815 to 820

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