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Cartilage

Properties of Cartilage

Chondrocytes Matrix
1. Avascular
Fibers
(collagen Type II, 2. Permeable
Fibers elastic) (conducts nutirents
and water)
Ground Substance
3. Flexible but Weight-Bearing
(hyaluronic acid,
chondroitin sulfate, (resistance to compression)
keritin sulfate,
60-70% H2O) 4. Elasticity and Resiliency

5. Resistance to Shear Forces

6. Slippery
(low friction at articular joints)

Isogenous 7. Poor Regenerative Capacity


Lacunae Group
Hyaline Cartilage Hyaline Cartilage

Matrix (amorphous & glassy)


hyaluronic acid
chondroitin sulfate
keratin sulfate chondrocyte nucleus
H2O (60-78%)
lacuna
Fibers- collagenous matrix
(invisible due to same
refractive index as matrix)

Typical Locations
Hyaline Cartilage (SEM)
intercostals (connect ribs
to the sternum)
wall of trachea & bronchii
articular cartilage of bone
epiphyseal plate
fetal axial skeleton
Fibrocartilage
Fibrocartilage- longitudinal section
Matrix collagenous fiber bundles
hyaluronic acid Fibrocartilage- SEM
chondroitin sulfate
keratin sulfate
Fibers
dense collagenous
bundles

Typical Locations

intervertebral discs Fibrocartilage- transverse section


pubic symphysis
meniscus of knee joint
attach tendons to bone
Properties
resistance to
compression and
shear forces
Elastic Cartilage Elastic Cartilage- pinnae of ear
Elastic Fibers
Matrix (resorcin-fuchsin stain)
hyaluronic acid
chondroitin sulfate
kertatin sulfate
Fibers
elastic (elastin)

Typical Locations
external ear
walls of external
auditory canal and
eustachian tubes Elastic Fibers- silver stain
epiglottis & larynx
bridge of nose
Properties
resiliency and
pliability
Growth of Cartilage

fibroblasts collagen

Perichondrium
perichondrium
Appositional
blood vessel Growth
chondroblasts
(peripheral mitosis
and differentiation
of fibroblasts)

hyaline
matrix

Interstitial
Growth
isogenous (mitosis of chondro-
groups cytes and deposition
(nests of of new matrix)
chondrocytes)

Territorial Matrix

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