Patholpgic Change in Emphysemia

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EMPHYSEMA

MS KRISHA PATEL
2nd YEAR BSC
NURSING (SEM – 3)
S.S.R.C.N VAPI
INTRODUCTION

Emphysema is a COPD characterized by


permanent enlargement of air sacs (alveoli)
distal to terminals bronchiole accompanied
by destruction of their wall , causing a
decrease in lungs function & often
breathlessness.
When the enlargement of air spaces is not
accompanied by destruction , it is known as
overinfection.
DEFINITION

• “ A disorder affecting the alveoli (tiny air


sacs) of the lung”.
• The transfer of oxygen & carbon dioxide in
the walls of the alveoli.
• In emphysema , the alveoli become
abnormally inflated , damaging their walls
and making it harder to breathe.
CAUSES
• Having cigarette smoking 80 – 90 % of all
emphysema.
• Less commonly by long - term exposure to air
pollution other lung irritants.
• Lungs Abscess.
• Occupational exposure to chemical irritants.
• Inherited genetic defects.
PATHOPHYSIOLOGY
• Normally functioning lungs are elastic , efficiently
expanding and recoiling as air passes freely
through the bronchus to the alveoli.
• When oxygen is moved into the blood and carbon
dioxide is filtered out.
• When a person inhales cigarette smoke or certain
other irritants, hid or her immune system responds
by releasing substances that are meant to defend
the lungs against the smoke.
CONTI…

• These substance can also attack the cells of the lungs ,


but the body normally inhibits such action with the
release of other substance.
• In smokers and those with the inherited defects ,
however, no such prevention occurs and the lung tissue
is damaged in such a way that it loses its elasticity.
• The small passageways leading to the alveoli collapse ,
trapping air within the alveoli.
CONTI…
• The alveoli , unable to recoil efficiently and move
the or out , over expand and rapture.
• As the disease progresses coughing and shortness of
breath respiratory disease , particularly chronic
bronchitis.
• Emphysema is most common among people aged 50
& older , most among men.
• The with inherited emphysema may experiences the
onset as early their thirties or forties .
PATHOLOGIC CHANGE
Grossly the alveoli are dilated , lungs are voluminous ,
pale with little blood.
Sub-pleural bullae ( air filled bubble like structure
formed by rupture of adjacent air spaces.) & bulging
outwards frame the surface of the lungs is seen in
advanced cases.
Microscopically , there is dilatation of septal walls of
respiratory bronchioles , alveolar sacs & ducts.
SYMPTOMES
1. The symptoms of emphysema develop
gradually over many years .
2. Shortness of breath .
3. Chronic mild cough ( thick sputum).
4. Sometimes weight loss are associated with
emphysema .
5. Emphysema patients may also develop an
enlarged or “ barrel” chest.
BARREL CHEST
CONTI…

6. Difficulty sleeping.
7. Moring headache
8. chronic fatigue
9. Swelling of the feet, ankles , legs.
10.Cyanosis.
CONTI…

11.Hyperinflation
12. Difficulty concentrating.
13.Wheezing.
14.Constant coughing or need to clear
the throat.
Hyperinflation
TREATMENT
Treating emphysema focuses on improving
emphysema symptoms:
• Smoking cessation
• Medication are usually prescribed to widen the airways
( bronchodilation).
• And reduce swelling in the airways .
• Antibiotics ( to treat lung infection).
 Oxygen therepy
CONTI..
Lungs volume reduction surgery .
( surgical removal of large areas of damage
lungs.)
 Pulmonary rehabilitation.
Lungs transplantation.
( This is the most drastic of emphysema
treatments.)
YOU

THANK

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