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    Development of Heart

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    Bishal Belbase
    The development of the heart begins around 3 weeks after fertilization from mesodermal tissue, forming two endocardial tubes that fuse to become the primitive heart tube. This primitive heart tube consists of five parts - truncus arteriosus, bulbus cordis, primitive ventricle, primitive atrium, and sinus venosus. Blood flows from the venous to arterial ends. The heart then undergoes looping and chamber formation to become the four-chambered heart.

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    Development of Heart

    Uploaded by

    Bishal Belbase
    26 views18 pages
    The development of the heart begins around 3 weeks after fertilization from mesodermal tissue, forming two endocardial tubes that fuse to become the primitive heart tube. This primitive heart tube consists of five parts - truncus arteriosus, bulbus cordis, primitive ventricle, primitive atrium, and sinus venosus. Blood flows from the venous to arterial ends. The heart then undergoes looping and chamber formation to become the four-chambered heart.

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    development of heart (1)

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    The development of the heart begins around 3 weeks after fertilization from mesodermal tissue, forming two endocardial tubes that fuse to become the primitive heart tube. This primitive heart tube consists of five parts - truncus arteriosus, bulbus cordis, primitive ventricle, primitive atrium, and sinus venosus. Blood flows from the venous to arterial ends. The heart then undergoes looping and chamber formation to become the four-chambered heart.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    26 views18 pages

    Development of Heart

    Uploaded by

    Bishal Belbase
    The development of the heart begins around 3 weeks after fertilization from mesodermal tissue, forming two endocardial tubes that fuse to become the primitive heart tube. This primitive heart tube consists of five parts - truncus arteriosus, bulbus cordis, primitive ventricle, primitive atrium, and sinus venosus. Blood flows from the venous to arterial ends. The heart then undergoes looping and chamber formation to become the four-chambered heart.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 18

    Development of heart

    Dr. Ashish Parajuli


    Junior Resident 2021 batch
    Department of Human Anatomy
    BPKIHS, Dharan
    • Development of heart begins after three weeks of fertilization.
    • It develops from the embryonic tissue called mesoderm.
    • Heart begins
    to develop
    near the head
    of embryo in a
    region known
    as a
    cardiogenic
    area.
    • Cardiogenic area begins to form two strands called cardiogenic cords
    after it receives chemical signals from endoderm.
    • Lumen develops in the cords and forms endocardial tubes.
    • Fusion of both endocardial tubes to form primitive heart tube.
    Primitive heart has
    following parts:

    1. Truncus arteriosus
    2. Bulbus cordis
    3. Primitive ventricle
    4. Primitive atrium
    5. Sinus venosus

    Direction of blood flow is from venous


    ends towards arterial ends.
    • Truncus arteriosus divides into
    ascending aorta and pulmonary trunk.
    • Bulbus cordis divides into conus and
    proximal part. Conus forms outflow
    tract of right and left ventricle,
    proximal part forms the right ventricle.
    • Primitive ventricle forms the left
    ventricle.
    • Bulboventricular sulcus arises
    between bulbus cordis and primitive
    ventricle which forms interventricular
    foramen and later interventricular
    septum.
    • Primitive atrium forms the anterior
    smooth part of both atrium.
    • Sinus venosus divides into body and
    right and left horn.
    • Body of sinus venosus forms the
    posterior part of right ventricle.
    • Left horn of sinus venosus is
    regressed to form coronary sinus.
    • Right horn of sinus venosus is
    absorbed into right atrium.
    • 3 sets of vein drain into right and
    left horn
    • Vitelline vein
    • Umbilical vein
    • Common cardinal vein
    • Right vitelline vein forms part of
    inferior venacava.
    • Right umbilical vein is regressed.
    • Right common cardinal vein forms a
    part of superior venacava.
    • Left horn and the vessels draining
    into it are regressed.
    Folding of Heart:
    • Elongated heart tube. forms a U shape and later into S shape
    Tetralogy of Fallot
    Persistent truncus arteriosus
    Development of blood vessels.
    • Right and left primitive aorta develops as a
    continuation of primitive heart tube.
    • Parts of primitive aorta:
    1. Ventral aorta: part lying anterior to
    foregut.
    2. Arched portion forming the first
    pharyngeal arch.
    3. Dorsal aorta: portion lying dorsal to
    gut.
    • Appearance of 2nd to 6th arches
    communicating with aortic sac.
    1. Greater part of 1st and 2nd
    arch disappear and forms
    maxillary artery and
    stapedial artery
    respectively.
    2. 5th arch disappears
    completely.
    3. Spiral septum of trunchus
    arteriosus extends into
    aortic sac in such a way
    that blood from pulmonary
    trunk passes only into 6th
    arch.
    4. Dorsal aorta grow cranially to form
    internal carotid artery.
    5. 3rd arch artery gives off a branch to
    reach cranially to form external carotid
    artery.
    6. Portion of aorta between 3rd and 4th
    arch artery called as ductus caroticus
    disappears.
    7. Portion of aorta from 4th arch to fusion
    of dorsal aorta also disappears.
    8. 4th arch on right forms right subclavian
    artery and on the left side forms arch of
    aorta from which the left subclavian
    artery arises.
    • Ascending aorta and
    pulmonary trunk: truncus
    arteriosus.
    • Brachiocephalic artery: aortic
    sac, left horn and left 4th arch
    artery.
    • Ductus arteriosus: from 6th
    arch, communicates
    pulmonary artery and aorta.

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