09 Lingkungan Pertanian

ENVIRONMENTAL HEALTH IN
AGRICULTURE
The basic requirements for a healthy

environment are said to include, clean air, safe
and sufficient water, adequate and safe food,
and a safe a peaceful place in which to live
• Agricultural health is the study of
environmental, occupational, dietary,
and genetic factors on the health of
farmers, farm families, pesticide
applicators, and others who work with
and are exposed to agricultural
chemicals.
• farming and agricultural work are associated
with high rates of occupational injury,
disability and illness.
• Agricultural work has a work accident death
rate that is similar to mining and construction
and that these three industries are the most
dangerous.
• Farmers and agricultural workers are at
increased risk for a variety of illnesses
including respiratory disorders, dermatologic
conditions, and cancer
• The farm is a unique workplace, few situations
the workers and their families often live at the
worksite. Thus, farm families may be at risk for
disease related to chronic environmental
exposures that occur outside the usual
definition of work.
• For example, acute pesticide poisoning during
application of pesticides. Chronic exposure to
lower levels of pesticides in the environment
on the farm (air, water, or food) may also be of
concern to the health of farm families.
Respiratory Disease
• There is a high prevalence of respiratory
symptoms in farmers. Much of the symptoms
reported in large surveys suggest the presence
of chronic bronchitis and the occurrence of
episodes of acute bronchitis.
• The problem goes beyond the mere presence
of symptoms. It is apparent that some farming
groups have accelerated declines in lung
function leading to chronic airflow obstruction
• The work environments with the highest risk
for chronic bronchitis are those with exposure
to grain dust, swine confinement buildings,
and poultry housing.
• vulnerable populations such as the elderly,
children, asthmatics and other susceptible
persons.
Cancer
• Farmers appear to experience elevated rates for
several cancers, including leukemia, non-Hodgkin’s
lymphoma, multiple myeloma, soft-tissue sarcoma,
and cancers of the skin, lip, stomach, brain, and
prostate.
• There was a positive correlation between atrazine
and leukemia, 2,4-D and leukemia, captan and
leukemia, atrazine and brain cancer, and atrazine
and testicular cancer, in Hispanic males
Arsenic
• High levels of arsenic exposure are thought to
cause reproductive, neurologic, respiratory,
hematologic, hepatic, diabetic, and dermal
disorders.
• They estimated that the 20 μg/L of arsenic
would cause an excess lifetime risk of 45
bladder cancers and 27 lung cancers for
10,000 males.
Reproductive health
• Many pesticides have been identified as
having endocrine and reproductive effects
based on animal toxicology studies :
dibromochloropropane, a nematocide
Other Health Effects
• Effects of pesticides and other agents on child
development, cardiovascular healthEffects of
pesticides and other agents on child development,
cardiovascular health
• Persons living near the intensive swine operations
who experienced the odors reported significantly
more tension, more depression, more anger, less
vigor, more fatigue, and more confusion than control
subjects as measured by the Profile of Mood States
exposures in agricultural work
• Organic dusts are the most common
respiratory exposures
• Toxic organic dusts can occur in association
with silage, grain dust, straw, wood chips, and
animal confinement buildings.
The major toxic components of organic dusts
• Derived from bacterial and fungal contamination such

as endotoxin, glucans, and mycotoxins.
• Endotoxin is a lipopolysaccharide component of the
cell wall of Gram-negative bacteria.
• Gram-negative bacteria air samples are Enterobacter,
Acinetobacter, Enterococcus, Moraxella,
Pseudomonas, and E.Coli.
• Glucans are cell wall components of fungi and molds
such as Aspergillus, Scopulariopsis, Pencillium,
Geotrichum, Mucor, and Fusarium.
Toxic gases
• Nitrogen dioxide is produced and accumulates
above the silage
• When nitrogen dioxide dissolves into water,
nitrous acid and nitric acid are formed.
• Nitrogen dioxide is an irritant to mucous
membranes. Less severe exposures cause cough,
headache, and dyspnea.
• After severe exposures acute pulmonary edema
may occur.
• Other sources of toxic gases are those emitted
from livestock confinementoperations, anure
pits, manure lagoons, and from sites of manure
land application
• The gases aregenerated from urine and feces and
also from microbial degeneration of manure
• the main gases of interest are hydrogen sulfide,
ammonia, methane, and carbon dioxide.
• Methane and carbon dioxide are dangerous at
very high concentrations and act as asphyxiants.
Hydrogen sulfide
• Hydrogen sulfide can be immediately toxic and
exposure to levels in excess of 100 ppm can
cause loss of consciousness and death
• The mechanism of this type of poisoning is
through effects on the oxygen transport system
in mitochondria.
• levels above 150 ppm it quickly poisons the
olfactory system, hindering the ability to detect
high levels through the sense of smell
Ammonia
• The mechanism of toxicity is through damage
to airway epithelium.
• Ammonia is water-soluble and is quickly
absorbed into airway secretions.
• Ammonia of 50 to 150 ppm will cause severe
cough and irritation of mucous membranes.
• Higher concentrations can cause permanent
scarring and massive exposures are fatal.
Odors
• More than 24 odorous chemicals have been
identified in the emissions from livestock
feeding operations
• Ammonia and hydrogen sulfide, described
above, are odorous. Volatile acids,
mercaptans, and amines
Water Pollution
• water pollution in the U.S. was estimated that
agriculture contributes to the impairment of at
least 173,529 river miles, 3,183,159 lake acres,
and 2,971 estuary square miles
• 20 % of the pollution from agriculture due to
intensive livestock feeding operations
• Manure pollution occurs from
• direct discharges from manure storage, lagoons,
stockpiles into surface water and from
application of manure onto fields
Ammonia
• Ammonia (both the ionized form, ammonium, and the
un-ionized form) is produced when microorganisms
break down organic nitrogen products in manure
• Ammonia is toxic to aquatic life and has been
responsible for fish kills.
• Ammonia is converted easily to nitrate and can lead to
nutrient overenrichment of surface waters. This can
lead to nuisance algae blooms which can lead to
reduced levels of dissolved oxygen, production of
chlorinated byproducts that are carcinogenic, and
clogging of water treatment facilities.
Nitrate
• The process of nitrification occurs in aerobic
environments and converts ammonium to nitrite
and then to nitrate.
• Nitrite is toxic to most fish but this is unusual
because of the rapid conversion to nitrate
• Nitrate is biologically available to plants and is a
valuable fertilizer
• Nitrate is however associated with health
effects in humans. Acute nitrate toxicity is due
primarily to its conversion to nitrite, which
oxidizes the Fe(+2) form of iron in hemoglobin
to the Fe(+3) state. This compound
methemoglobin) does not bind oxygen,
resulting in reduced oxygen carrying capacity
of the blood.
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ENVIRONMENTAL HEALTH IN

The basic requirements for a healthy

• Derived from bacterial and fungal contamination such

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