Drosophila Mutants

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Notation

In fruit fly genetics, the normal fly is called a "wild type" and
any fly exhibiting a phenotypic mutation is called a "mutant".

Mutant flies are given names that generally denote the type
of mutation the fly exhibits.
For example, the mutant "ebony" has a much darker body
than the wild type fly.

The wild type fly is denoted by a superscript + over the


mutant letter code. For example, e+ denotes a wild type fly
for the ebony body trait - meaning it has normal body color
(not ebony)
What about notations on Sex
Chromosomes?
Under normal diploid conditions a female fruit fly
has two X chromosomes, a male has an X and a Y
chromosome. Sex-linked genes are located on one of
the sex chromosomes (usually the X chromosome).
Thus, the genotypic notation for a mutant gene for
white eye color on the X chromosome would look
like:

• Xw Xw = white-eyed female
• Xw+Xw = wild type heterozygote female
• Xw Y = white-eyed male
• Xw+ Y = wild type male
Mutant Phenotypes

Dominant: The first letter of the


symbol is in Upper case.
Ultrabithorax- Ubx1

Recessive- small case


Ebony- e
Body Colour mutants
Wing morphology mutants
Bristles morphology mutants
Eye colour mutants
Eye shape mutants
Body size (Tubby)
Today’s Exercise

VIAL A- white eyed and Red eyed flies

VIAL B= Black body and others

VIAL C- Wild type flies

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