Diabetes Mellitus-Insulin 9-19-18 Student Vers
Diabetes Mellitus-Insulin 9-19-18 Student Vers
Diabetes Mellitus-Insulin 9-19-18 Student Vers
Learning Lab
Week #4
September 18 & 19
Jennifer Briggs MSN, RN
Healthy Person
Insulin released in continuous small
increments
BASAL rate-steady glucose level in
bloodstream
Release of insulin is after ingestion of
food leads to:
Lowering blood glucose level to a normal
stable range
NORMAL fasting range: 70-99 mg/dL
2
Diabetes Mellitus
A chronic multisystem disease
related to
Abnormal insulin production
Impaired insulin utilization
Or both
3
Diabetes Mellitus (cont.)
Leading cause of
End-stage renal disease
Adult blindness
Non-traumatic lower limb
amputations
Major contributing factor
Heart disease
Stroke
4
Etiology and Pathophysiology
Two most common types
Type 1
Type 2
Other types
Gestational
Prediabetes
Secondary diabetes
5
Type 1
No insulin produced by pancreas
Requires exogenous insulin
6
Clinical Manifestations
Type 1 Diabetes Mellitus
Classic symptoms
Polyuria (frequent urination)
Polydipsia (excessive thirst)
Polyphagia (excessive hunger)
Weight loss
Weakness
Fatigue
7
Type 2
The most common type of diabetes
Body has decreased production or
resistance to insulin
Production of SOME ENDOgenous
insulin
Usually onset is gradual & can go
undetected for years
8
Type 2 Diabetes Mellitus
Most prevalent type of diabetes
90-95% of patients with this disease
Usually occurs in people over 30 years
of age
80% to 90% of patients are
overweight.
9
Type 2 Diabetes
Prevalence increases with age.
Genetic basis
Obesity (abdominal/visceral)
Most powerful risk factor
Greater in some ethnic populations
African Americans, Asian Americans,
Hispanic Americans, and Native
Americans
Native Americans and Alaskan Natives:
Highest rates of diabetes in the world
10
Insulin
Normal insulin metabolism
Released continuously into
bloodstream in small increments with
larger amounts released after food
Stabilizes glucose range to 70 to
120 mg/dL
Decreases glucose in the bloodstream
11
Normal Insulin Secretion
12
Question 1
Analyze the following diagnostic findings
for your patient with type 2 diabetes.
Which result will need further
assessment?
a) A1C 9%
b) BP 126/80 mmHg
c) FBG 90 mg/dL
d) LDL cholesterol 100 mg/dL
13
Goals for Glycemic Control
A1C > 6.5% A1C > 6.5%
16
Diabetes Mellitus
Diagnostic Studies
Hemoglobin A1C (cont’d)
Regular assessments required
Ideal goal
American College of Endocrinology <6.5%
Normal A1C reduces risks of
Retinopathy
Nephropathy
Neuropathy.
17
Diabetes Mellitus
Collaborative Care
Goals of diabetes management
Decrease symptoms.
Promote well-being.
Prevent acute complications.
Delay onset and progression of
long-term complications.
18
Objective
Describe S/S of
hypoglycemia & hyperglycemia
19
Hypoglycemia
Low blood glucose
Occurs when
Too much insulin in proportion to glucose in
the blood
Blood glucose level less than 70 mg/dL
20
Hypoglycemia (cont’d)
Manifestations
Cold, clammy skin
Numbness of fingers, toes, mouth
Rapid heartbeat
Emotional changes
Nervousness, tremors
Faintness, dizziness
Hunger
Changes in vision
Seizures, coma
21
Hypoglycemia (cont’d)
Hypoglycemic unawareness
Person does not experience
warning signs/symptoms,
increasing risk for decreased
blood glucose levels
Related to autonomic
neuropathy
22
Hypoglycemia (cont’d)
Causes
Mismatch in timing
Food intake & peak action of
insulin or oral hypoglycemic
agents
23
Hypoglycemia (cont’d)
At the first sign
Check blood glucose
If <70 mg/dL, begin treatment
If >70 mg/dL, investigate further for
cause of signs/symptoms
If monitoring equipment not
available, treatment should be
initiated
24
Hypoglycemia (cont’d)
Treatment
If alert enough to swallow
15 to 20 g of a simple
carbohydrate
4 to 6 oz fruit juice
Regular soft drink
Avoid foods with fat
decreases absorption of
sugar 25
Hypoglycemia (cont’d)
Treatment
If alert enough to swallow
Recheck blood sugar 15 minutes after
treatment.
Repeat until blood sugar >70 mg/dL.
Patient should eat regularly scheduled
meal/snack to prevent rebound
hypoglycemia.
Check blood sugar again 45 minutes after
treatment.
26
Hypoglycemia (cont’d)
Treatment
Patient not alert enough to swallow
Administer 1 mg of glucagon IM or
subcutaneously.
Have patient ingest a complex
20 to 50 mL of 50% dextrose IV
push
27
Hyperglycemia
High blood glucose
Elevated blood glucose levels: FBG > 126
mg/dL
2 Hr plasma glucose level > 200 mg/dL
A1C > 6.5%
Increased urine output
Increased appetite
Fatigue
28
Hyperglycemia
Manifestations
High blood glucose
Increased urination
Increased appetite followed by lack of
Weakness, fatigue
Blurred vision
Headache
Glycosuria
Abdominal cramps
Nausea/vomiting
29
Hyperglycemia
Causes:
Illness
Infections
Corticosteroids
Too much food
Not enough insulin
Inactivity
Stress
Poor absorption of insulin
30
Hyperglycemia
Treatment
Check Blood sugar frequently
Treat with ordered medication
Check for ketones
Increase fluids (at least on hourly basis)
31
Question 2
What is the priority action for the nurse to
take if the patient with type 2 diabetes
complains of blurred vision?
a) Call the physician.
b) Administer insulin as ordered.
c) Check the patient’s blood glucose level.
d) Assess for other neurologic symptoms.
32
Insulin Types
Most common:
Rapid acting
Short acting
Intermediate acting
Long acting
33
Drug Therapy
Insulin
Types of insulin
Insulins differ by
onset
peak action
duration
34
Sliding Scale
Sliding scale therapy approximates
daily insulin requirements.
The term "sliding scale" refers to the
progressive increase in pre-meal or
nighttime insulin doses.
35
Sliding Scale Principles
The amount of CHO (carbohydrate) to be
eaten at each meal is pre-set.
The basal (background) insulin dose does
not change.
You take the same long-acting insulin
dose no matter what the blood glucose
level.
The bolus insulin is based on the blood
sugar level before the meal or at bedtime
36
Mixing Insulins
Fig. 49-3. Commercially available insulin preparations showing onset, peak, and duration of action.
37
Drug Therapy
Insulin
Types of insulin (cont’d)
Rapid-acting: Lispro (Humalog), Aspart
(Novolog), and glulisine (Apidra)
Short-acting: Regular
Intermediate-acting: NPH
Long-acting: Glargine (Lantus), detemir
(Levemir)
38
Objective
Compare and contrast the use of
insulin by basal and bolus.
39
Drug Therapy
Insulin
Regimen that closely mimics
endogenous insulin production is
basal-bolus.
Long-acting (basal) once a day
Rapid/short-acting (bolus) before meals
40
Drug Therapy
Insulin
Insulin preparations
Rapid-acting (bolus)
Lispro, aspart, glulisine
Injected 0 to 15 minutes before meal
Short-acting (bolus)
Regular
Injected 30 to 45 minutes before meal
41
Drug Therapy
Insulin
Long-acting (basal)
Injected once a day at bedtime or in
the morning
Released steadily and continuously
No peak action
insulin or solution
42
Insulin Regimens
Bolus (Mealtime Basal (Long- or
insulin) Intermediate-Acting)
To control postmeal In addition to
blood glucose (BG) mealtime insulin
levels Must also use long-
Timing of rapid-acting acting basal or
& short-acting insulin intermediate-acting
in relation to meals is insulin to control BG
CRUCIAL levels in between
meals & overnight
Drug Therapy
Insulin
Administration of insulin
Cannot be taken orally
Subcutaneous injection for
self-administration
IV administration (acute care)
44
Drug Therapy
Insulin
Administration of insulin (cont’d)
Fastest absorption from abdomen,
followed by arm, thigh, and buttock
Abdomen is the preferred site.
Rotate injections within one particular
site.
Do not inject in site to be exercised.
Usually available as U100
1 mL contains 100 units of insulin.
45
Subcutaneous Injection Sites
46
Drug Therapy
Insulin
Administration of insulin (cont’d)
Hand washing with soap adequate
Do not recap needle after administration
45- to 90-degree angle, depending on fat
thickness of the patient
Insulin pens preloaded with insulin are
now available.
47
Drug Therapy
Insulin
Insulin pump
Continuous subcutaneous infusion
Battery-operated device
Connected via plastic tubing to a
catheter inserted into subcutaneous
tissue in abdominal wall
Potential for tight glucose control
48
Objective
49
Blood Glucose Monitoring
Skill 35.4 Pg 1256-1259 Taylor
1. Perform hand hygiene.
2. Remove reagent strip from
container.
3. Check code on test strip vial.
4. Insert strip into glucose meter
5. Apply clean gloves
6. Choose puncture site
50
Blood Glucose Monitoring (cont.)
7. Hold finger to puncture in dependent
position
8. Clean site with antiseptic swab &
allow to dry
9. Prepare lancet & hold it perpendicular
to puncture site
10. Wipe away first droplet of blood w/
gauze
51
Blood Glucose Monitoring (cont.)
11. Collect large droplet.
12. Obtain test results.
13. Turn meter off, dispose of test strip,
lancet & gloves properly.
14. Discuss test results with patient.
15. Record test results.
52
Objective
Demonstrate how to accurately obtain
blood glucose reading from a glucometer
53
Performing BG Testing
Nursing Videos-Intermediate
Specimen collection
Performing Blood Glucose Testing
54
Monitoring Blood Glucose
Self-monitoring of blood glucose
(SMBG)
Enables patient to make self-
management decisions regarding diet,
exercise, and medication
55
Monitoring Blood Glucose
Self-monitoring of blood glucose
(SMBG) (cont’d)
Important for detecting episodic
hyperglycemia & hypoglycemia
Patient training is crucial.
Supplies immediate information about
blood glucose levels
56
Monitoring Blood Glucose
Continuous glucose monitoring
Displays glucose values with updating
every 1 to 5 minutes
Help identify trends and track patterns
57