Journal Bilu
Journal Bilu
Journal Bilu
BILU.B
CRRI
Tuberculosis osteomylitis is a chronic
granulomatous systemic infectious disease
caused by mycobacterium tuberculosis.
The oral lesion found in the oral cavity is
relatively rare and may present as
ulcers,erythematous patches,indurated
lesions,nodules or bony jaw lesions.
This journal document a case of tuberculous
osteomylitis of maxilla in 19 yr old female
patient,who was initially treated for multiple
periodontal abcesses,which later proved to be
tubercular osteomylitis of maxilla.
OSTEOMYLITIS:
Osteomylitis is the inflammation of
the bone marrow that produces clinically
apparent pus and secondarily affects the
calcified components.It infects all the three
components of the bone like
periosteum,cortex &marrow.
Odontogenic infection
Compound fracture of the jaws
Traumatic injury
Middle ear infection and respiratory
infection
Peritonsillar abscess
ACCORDING TO ANATOMIC LOCATION:
-Intramedullary
-Subperiosteal
-Periosteal
ACCORDING TO DURATION AND SEVERITY:
-Acute
-Chronic
DEPENDING ON PRESENCE OR ABSENCE OF
SUPPURATION:
*SUPPERATIVE:
-Acute suppurative osteomylitis.
-Chronic suppurative osteomylitis.
-Infantile osteomylitis.
*NON SUPPURATIVE :
-Chronic nonsuppurative osteomylitis
focal sclerosing
diffuse sclerosing
-Radiation osteomylitis.
-Garre’s sclerosing osteomylitis
-Osteomylitis due to specific infection:
actinomycosis
tuberculosis
syphilis
Staphylococcus aureus
Staphyloccus albus
Hemolytic streptococci
GRAM NEGATIVE ORGANISM:
Klebsiella
Psudomonas
Protease
E.coli
ANAROBIC BACTERIA
Prepto streptococcus
Bacteriods
Fusobacterium
OTHERS
Mycobacterium tuberculosis
Treponema palladum
ACUTE LESIONS: Severe pain,parasthesia,intra
medullary lesions.
pus exudates from gingival sulcus,cellulitis
and no swelling &sinus formation.
CHRONIC LESIONS: Slight pain with swelling
of jaw and sequestra formation & intraoral
and extraoral formation of sinus,tender on
palpation.
INTIAL STAGE:Spontaneous(localised).
ACUTE STAGE:Severe pain ,soreness &looseness
of the involved tooth.
-Early acute stage:pain adjacent tooth and
side of jaw.
-Late acute stage:Parasthesia of lip.
OSTEONECROTIC STAGE:
Diminished spontaneous pain
abcess formation
pus discharge
SEQUESTRUM STAGE:Segments of necrotic bone
become detached.
Pagets disease
Eosinophilic granuloma.
Incision and drainage
Irrigation & debridement of necrotic areas.
Empiric therapy:
Regimen I:Aqueous penicillin 2 million
units IV ,4 hourly +oxacillin 1g IV 4hourly .
Regimen II:If pt is asympyomatic after 48 -
72 hrs,then penicillin IV 500 mg ,6hourly &
dicloxacillin 250 mg 4 hourly for 2-4 weeks.
Extraction of infected tooth.
Sequestromy
Saucerization
Closed wound irrigation and suction.
Decortication.
Resection and immediate reconstruction.
Hyperbaric oxygen therapy.
Supportive therapy.
adequate rehydration
rich nutritional diet
vitamin therapy
Tuberculosis is a chronic granulomatous
systemic infectious disease.
Caused by MYCOBACTERIUM TUBERCULOSIS.
Oral tuberculosis is rare.
Oral lesion may present as
ulcer, erythematous patches,indurated
lesion,nodules ,bony jaw lesion.
Oral lesion is due to inoculation of
tuberculosis bacilli in to oral tissue.
Tuberculosis in jaw is more common in
children below age of 18yrs.
TUBERCULOSIS INFECTIONS
PRIMARY SECONDARY
RADIOGRAPHIC REPORT:
-PANORAMIC EXAMINATION:
Diffuse bone loss in the maxilla involving all
maxillary teeth.
-CHEST X-RAY:
Pulmonary koch’s were found.
HISTOPATHOLOGICAL REPORT:
-CYTOLOGICAL SMEAR:
Polymorphonuclear leucocytes &few
lymphocytes.
-FINE NEEDLE ASPIRATION (FNAC):
Granulomatous lesion.
Diagnosis pulmonary tuberculosis as a
primary lesion with secondary lesion in the
maxilla.
ANTI TUBERCULOUS FOR BONE TUBERCULOSIS
DRUGS:
Rifampicin
Isoniazid
Ethambutol
Streptomycin
After four week follow up,marked
improvement in over all health was
noticed,with over all reduction in the mobility
of maxillary bone.
Tuberculosis still remains a dreaded disease.
Primary Oral Tuberculosis is rare because of
various barriers present in the oral cavity,
intact oral mucosa
salivary enzymes
tissue antibodies
oral saprophytes
Any breach in these barries can lead to
infection by the tubercle bacilli.
Tuberculous osteomylitis is even rare and
constitutes less than 2% of skeletal TB.
Involvement of maxillary is extremely rare.
Diagnosis:clinical findings,radiographs &
sputum examination.
Recent methods:DNA probe & polymerase
chain reaction assays.
Tuberculous Osteomylitis of the maxilla is an
extremely rare condition of the oral cavity.It
can present in an unusual form in the oral
cavity and can be misdiagnosed.
Tuberculosis must always be included in the
differential diagnosis.
Before diagnosing the oral tuberculosis must
locate the primary site in the body.
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