Complex Inheritance Patterns
Complex Inheritance Patterns
Complex Inheritance Patterns
Human Genetics
Incomplete Dominance
The
phenotype of the
heterozygous is
intermediate between
those of the two
homozygous
individuals.
Neither allele is
completely dominant.
Incomplete dominance
Incomplete Dominance
In
__________
X _________
Codominance
The
phenotypes of both
homozygous individuals
are visible in
heterozygous individuals.
Both alleles are
expressed equally.
EX: Red horse (RR)
crossed with a white
horse (WW) results in
roan (RW)
In
__________X________
Codominance
Codominance in Humans
Sickle cell carriers
Heterozygous
Multiple Allelic
Traits
controlled
by more than two
alleles
EX:
GENOTY
PES
IAIA
IAi
IBIB
IBi
IAIB
ii
RESULTING
PHENOTYPES
Type A
Type A
Type B
Type B
Type AB
Type O
There is a 75% (3 of 4)
chance that the child
will be Type B,
and a 25% (1 of 4)
chance that the child
will inherit Type O (ii).
With some careful thinking we don't even need to do the psquare thing. Jill is Type O, meaning her genotype is "ii".
This means that her parents each have at least one "i" in
their genotype (since she inherited one from each parent).
Since one brother is Type B, one of the parents must have
the IB allele, making that parent IBi.
And since the other brother is Type A, the other parent
must have the IA allele & have a genotype of IAi.
There you have it. Jill's parents are IAi & IB , and her
brothers shouldn't be so mean. on to #6
type
Importance:
Mixing incompatible blood causes clumping
resulting in death.
Determining parentage
Sex-Linked Inheritance
Traits
X-linked traits
EXAMPLE: Drosophilia
In males fruit flies, eye color is carried on the X chromosome.
Red eyes (R) is dominant to white (r).
If a male inherits a single recessive allele (r ) he will have
white eyes. If a female inherits a single recessive allele
(r ) she will have red eyes.
Male XrY white eyes
Male XRY red eyes
Cant
differentiate b/w
red and green.
Trouble
identify red
and green traffic lights.
Hemophilia
X-linked disorder
Inability to clot.
Males inherit from carrier
mothers.
Females need two
recessive alleles.
Treated with transfusions,
injecting blood clotting
enzyme.
Polygenic Inheritance
The
All
Polygenic Inheritance in
Humans
Skin
color
color
Height
stature, hair color, and
body shape
Environmental Influences
The
Many
Environmental Influences
External
Internal
Temperature
Hormones
Nutrition
Structural differences
Light
Age
Chemicals
Infectious agents