Ghadeer Al-Shaikh

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Ghadeer Al-Shaikh, MD, FRCSC

Assistant Professor & Consultant


Obstetrics & Gynecology
Urogynecology & Pelvic Reconstructive Surgery
Department of Obstetrics & Gynecology
College of Medicine
King Saud University

Obstetrics is "bloody business."

Death from hemorrhage still remains a


leading cause of maternal mortality.

Causes of 763 Pregnancy-related Deaths Due to Hemorrhage


Causes of Hemorrhage

Number (%)

Abruptio placentae

141 (19)

Laceration/uterine rupture

125 (16)

Uterine atony

115 (15)

Coagulopathies

108 (14)

Placenta previa

50 (7)

Placenta accreta / increta / percreta

44 (6)

Uterine bleeding

47 (6)

Retained placenta

32 (4)

APH is blood loss Per vagina after 20


weeks gestation.

Complicates close to 4% of all


pregnancies and is a MEDICAL
EMERGENCY!

Is one of the leading causes of


antepartum hospitalization, maternal
morbidity, and operative intervention.

Placental Abruption
Placenta Previa
Uterine Rupture
Vasa Previa
Bloody Show
Coagulation Disorder
Hemorrhoids
Vaginal Lesion/Injury
Cervical Lesion/Injury
Neoplasia

The pregnancy in which such bleeding


occurs remains at increased risk for a
poor outcome even though the bleeding
soon stops and placenta previa appears
to have been excluded by sonography.

Defined as a placenta implanted in the lower


segment of the uterus, presenting ahead of the
leading pole of the fetus.
1.

Total placenta previa. The internal cervical os is covered


completely by placenta.

2.

Partial placenta previa. The internal os is partially


covered by placenta.

3.

Marginal placenta previa. The edge of the placenta is at


the margin of the internal os.

4.

Low-lying placenta. The placenta is implanted in the


lower uterine segment such that the placenta edge
actually does not reach the internal os but is in close
proximity to it.

Bleeding results from small


disruptions in the placental
attachment during normal
development and thinning of
the lower uterine segment

Incidence about 1 in 300

Perinatal morbidity and mortality are


primarily related to the complications of
prematurity, because the hemorrhage is
maternal.

Etiology:
Advancing maternal age
Multiparity
Multifetal gestations
Prior cesarean delivery
Smoking
Prior placenta previa

The most characteristic event in placenta


previa is painless hemorrhage.

This usually occurs near the end of or


after the second trimester.

The initial bleeding is rarely so profuse as


to prove fatal.

It usually ceases spontaneously, only to


recur.

Placenta previa may be associated with


placenta accreta, placenta increta or
percreta.

Coagulopathy is rare with placenta


previa.

The simplest and safest method of placental


localization is provided by transabdominal
sonography.

Transvaginal ultrasonography has substantively


improved diagnostic accuracy of placenta previa.

MRI

At 18 weeks, 5-10% of placentas are low lying.


Most migrate with development of the lower
uterine segment.

Admit to hospital

NO VAGINAL EXAMINATION

IV access

Placental localization

Severe
bleeding
Moderate
bleeding

Resuscitate
>34/52
Gestation
<34/52
Resuscitate
Steroids

Mild
bleeding

Caesarean
section

Gestation

<36/52
>36/52

Unstable
Stable
Conservative
care

Delivery is by Caesarean section

Occasionally Caesarean hysterectomy


necessary.

Defined as the premature separation of


the normally implanted placenta.

Occurs in 1-2% of all pregnancies

Perinatal mortality rate associated with


placental abruption was 119 per 1000
births compared with 8.2 per 1000 for all
others.

external hemorrhage
concealed hemorrhage
Total
Partial

What are the risk factors for placental


abruption?

The primary cause of placental abruption is unknown, but


there are several associated conditions.

Increased age and


parity

Cigarette smoking

Thrombophilias

Preeclampsia

Cocaine use

Chronic hypertension

Prior abruption

Preterm ruptured
membranes

Uterine leiomyoma

External trauma

Multifetal gestation

Hydramnios

Pathology

Placental abruption is initiated by hemorrhage


into the decidua basalis.

The decidua then splits, leaving a thin layer


adherent to the myometrium.

development of a decidual hematoma that leads


to separation, compression, and the ultimate
destruction of the placenta adjacent to it.

Bleeding with placental abruption is


almost always maternal.

Significant fetal bleeding is more likely to


be seen with traumatic abruption.

In this circumstance, fetal bleeding


results from a tear or fracture in the
placenta rather than from the placental
separation itself.

The hallmark symptom of placental abruption is pain


which can vary from mild cramping to severe pain.

A firm, tender uterus and a possible sudden increase


in fundal height on exam.

The amount of external bleeding may not accurately


reflect the amount of blood loss.

Importantly, negative findings with ultrasound


examination do not exclude placental
abruption. Ultrasound only shows 25% of
abruptions.

Shock

Consumptive Coagulopathy

Renal Failure

Fetal Death

Couvelaire Uterus

Management: Treatment for placental


abruption varies depending on gestational age
and the status of the mother and fetus.
Admit
History & examination
Assess blood loss
Nearly always more than revealed

IV access, X match, DIC screen


Assess fetal well-being
Placental localization
Delivery

Reported in 0.03-0.08% of all delivering


women, but 0.3-1.7% among women with a
history of a uterine scar (from a C/S for
example)

13% of all uterine ruptures occur outside the


hospital

The most common maternal morbidity is


hemorrhage

Fetal morbidity is more common with extrusion

Classic presentation includes vaginal


bleeding, pain, cessation of contractions,
absence/ deterioration of fetal heart rate,
loss of station of the fetal head from the
birth canal, easily palpable fetal parts, and
profound maternal tachycardia and
hypotension.

Patients with a prior uterine scar should


be advised to come to the hospital for
evaluation of new onset contractions,
abdominal pain, or vaginal bleeding.

What are the risk factors


associated with uterine
rupture?

Excessive uterine
stimulation

Multiparity

Non-vertex fetal
presentation

Hx of previous C/S

Trauma

Shoulder dystocia

Prior rupture

Forceps delivery

Previous uterine
surgery

Management: Emergent laparotomy

Rarely reported condition in which the


fetal vessels from the placenta cross the
entrance to the birth canal.

Incidence varies, but most resources note


occurrence in 1:3000 pregnancies.

Associated with a high fetal mortality rate


(50-95%) which can be attributed to rapid
fetal exsanguination resulting from the
vessels tearing during labor

There are three causes typically noted for


vasa previa:
1. Bi-lobed placenta
2. Velamentous insertion of the umbilical cord
3. Succenturiate (Accessory) lobe

Risk Factors:

Bilobed and succenturiate placentas

Velamentous insertion of the cord

Low-lying placenta

Multiple gestation

Pregnancies resulting from in vitro fertilization

Palpable vessel on vaginal exam

Management:

When vasa previa is detected prior to labor, the


baby has a much greater chance of surviving.

It can be detected during pregnancy with use of


transvaginal sonography.

When vasa previa is diagnosed prior to labor,


elective caesarian is the delivery method of
choice.

Is a blood test used to measure the


amount of fetal hemoglobin transferred
from a fetus to the mother's bloodstream.

Used to determine the required dose of


Rh immune globulin.

Used for detecting fetal-maternal


hemorrhage.

The test allows the clinician to determine


whether the blood originates from the infant or
from the mother.

Place 5 mL water in each of 2 test tubes

To 1 test tube add 5 drops of vaginal blood

To other add 5 drops of maternal (adult) blood

Add 6 drops 10% NaOH to each tube

Observe for 2 minutes

Maternal (adult) blood turns yellow-green-brown; fetal


blood stays pink.

If fetal blood, deliver STAT.

Admit
History
Examination
NO PV
Nurse on side
IV access/
resuscitate
Clotting screen
Cross match

Kleihauer-Betke test
Apt test
CTG
Observation
Placental localization
Speculum
examination when
placenta previa
excluded
Anti-D if Rh-negative

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