Normocytic Anemia's
Normocytic Anemia's
Normocytic Anemia's
Normocytic anemias
Normocytic anemias are classified as
anemias with a mean (average) corpuscular
volume (RBC volume), decreased
heamatocrit and hemoglobin levels
These types of anemias are typical found in
elderly patients (85yrs and older) but can
be seen in ages as early as 44yrs.
The prevalence of these anemias increases
with age and can be found predominately in
males
Causes
Malnutrition
Malabsorption
Poor dieting
Mixture of macro and microcytic
anemia
B2 Deficiency
(ariboflavinosis)
Dietary deficiency of riboflavin (ariboflavinosis) is
characterized by sore throat
cheilosis (lesions on the lips)
angular stomatitis (lesions on the angles of the mouth)
glossitis: fissured and bright pink colored tongue)
normocytic, normochromic anemia
Severe riboflavin deficiency may affect the conversion
of vitamin B6 to its coenzyme, as well as conversion of
tryptophan to niacin.
Concentrations <1 mcg/L are considered significantly
diminished
Treatment
measurement of urinary riboflavin can be used to
confirm riboflavin deficiency.
Treatment generally involves oral riboflavin
supplements
a dosage of 2 to 10 mg is to be administered 3 times
daily until symptoms improve
The dosage is reduced to 2 to 4 mg once daily until
you completely recover.
Failure of oral supplements are can be compensated
for via riboflavin injections.
higher doses are recommended for pregnant and
lactating women.
Types of Normocytic
anemias (NA)
Anemia of Chronic Disease
Aplastic anemia
Anemia resulting form sickle cell
disease (not SC anemia)
B2 deficiency anemia
B6 deficiency anemia
Fatigue
Shortness of breath
Dizziness
Cold sensation in hands and feet
WBC:
Fever
Frequent infection
PLTS:
Bleeding gums
Easily bruised, easy to bleed
Abnormally long bleeding
Heavy menstruate
Nose bleeds
Physical examination
History
Blood count
etc
Aplastic anemia
REFERENCES
National Center for Biotechnology
Information, . ( 2014, June 11).Aplastic
Anemia.Retrieved March 9, 2015, from
http://www.ncbi.nlm.nih.gov/pubmedhealt
h/PMH0062936
Brill JR, Baumgardner DJ (2000,
November).Normocytic anemia.Retrieved
March 9, 2015, from
http://www.ncbi.nlm.nih.gov/pubmed/1112
6852
REFERENCES
Elson M. Haas, M.D (2006).Treatment for a Riboflavin
Deficiency.Retrieved March 11, 2015, from
http://www.livestrong.com/article/427637-treatment-for-ariboflavin-deficiency/
Mayo Clinic. (N/A). Riboflavin (Vitamin B2), Plasma. Retrieved
March 11, 2015, from
http://www.mayomedicallaboratories.com/testcatalog/Clinical+and+Interpretive/61637
Larry E. Johnson, MD, PhD
(2014,October ).Riboflavin.Retrieved March 11, 2015, from
http://www.merckmanuals.com/professional/nutritional_disorde
rs/vitamin_deficiency_dependency_and_toxicity/riboflavin.htmlSee more at: http://reffor.us/index.php#sthash.cnpQM46v.dpuf