Common Eye Problems

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COMMON EYE PROBLEMS:

THE RED EYE

William A. Curry, MD
GIM Noon Conference
March 27, 2007
Goals for this talk
1. What are some acute or subacute
eye conditions internists are likely to
encounter?
2. Which ones need referral right away?
3. What should we do for the rest?
CASE ONE
 27 yo WM prisoner brought by police from
jail for “headache”
 Pain in right eye and right side of head and
face
 One week, progressive pain now intense
 Moderately injected conjunctiva, cloudy
cornea
 Can see only finger-counting
 Neuro exam otherwise normal
CASE ONE
CASE ONE
 Referred emergently
 DX: Acute narrow angle glaucoma,
intraocular pressure very high
 Controlled with midriatic and Beta blocker
eye drops
 No improvement in vision
 TEACHING POINTS
 Acute glaucoma can be confused with various
headache syndromes.
 Recognizing true source of pain prevents
unnecessary delay of extended neuro eval.
 Early intervention is crucial to preserve vision.
WHAT SYMPTOMS REQUIRE
IMMEDIATE REFERRAL of RED EYE?

1. Unilateral red eye with N/V


2. Severe ocular pain
3. Loss of visual acuity
WHAT CONDITIONS REQUIRE
IMMEDIATE REFERRAL OF RED EYE?
 Keratitis (infection of cornea)
 Hyphema (blood in anterior chamber)
 Hypopyon (pus in anterior chamber)
 Acute glaucoma
 Penetrating trauma
IMMEDIATE REFERRAL

Keratitis
(herpes)

Keratitis (aspergillus)

Keratitis (fusarium)
IMMEDIATE REFERRAL
Hyphema
(blood in ant. chamber)

Hypopyon
(pus in ant. chamber)
IMMEDIATE REFERRAL

Penetrating trauma
EXAMINATION OF THE RED EYE
 General Observation
 Measurement of Visual Acuity
 Penlight Examination
 Funduscopic Examination
General Observation of Red Eye
 Foreign Body sensation/photophobia?
 YES: Worry about keratitis, uveitis/iritis,
angle closure glaucoma
 Associated Rheumatic d/o or IBD?
 YES: Worry about scleritis, episcleritis
 Allergic or URI symptoms?
 YES: Viral or allergic conjunctivitis likely
Visual Acuity of the Red Eye
 Formal Snellen chart at 20 ft. not
necessary – looking for gross changes.
 Can patient read what ordinarily
he/she could easily see?
 Use hand-held acuity chart or reading
material.
Penlight Exam of Red Eye
 Reaction to light?
 Mid-dilation and fixed:
angle closure glaucoma
 1-2 mm, pinpoint: corneal
abrasion, keratitis, iritis
 Purulent discharge?
 Corneal opacity: bacterial keratitis
 No corneal opacity:
bacterial conjunctivitis
Penlight Exam of Red Eye
 Pattern of Redness?
 Diffuse (bulbar and palpebral conjuntivae):
conjunctivitis of any cause.
 Ciliary “flush”: more injected at limbus
(junction of sclera and cornea) in keratitis,
iritis, angle closure.
 Corneal white spot, opacity, or foreign
body?
 Yes: Keratitis or foreign body
RED FLAG FOR RED EYES =
CILIARY FLUSH (at limbus)
 SCLERITIS
 Painful, potentially blinding
 50% assoc. w/systemic
illness (RA, Wegener’s)
 Need topical steroids by ophthalmologist
 EPISCLERITIS
 Abrupt onset, watery irritation
 Does not threaten vision
 Ophthalmology to r/o scleritis
 Assoc. w/RA, IBD, vasculitides,
zoster, Lyme
Penlight Exam of Red Eye
 Does a corneal defect take up fluorescein?
 YES: keratitis, corneal abraision
 NO: foreign body
 Blood (hyphema) or pus
(hypopyon) in anterior chamber?
 Hyphema: blunt or penetrating
trauma
 Hypopyon: infectious keratitis,
endophthalmitis, Behcet’s
FUNDUSCOPIC EXAM IN RED EYE
 Not necessary
RED EYE NOT NEEDING REFERRAL
 Vision not affected
 Pupil reacts to light
 No foreign body
sensation/photophobia
 No corneal opacity
 No hypopyon or hyphema
CONJUNCTIVITIS
 INFECTIOUS
 Bacterial
 Viral
 NON-INFECTIOUS
 Allergic
 Non-allergic
BACTERIAL CONJUNCTIVITIS
 Adults: Staph. Aureus
 Children: S. pneum., H. flu,
Moraxella
 Highly contagious
 Purulent discharge often awakening
with eye stuck shut (“matted up”), +/- bilat.
 Usually self-limited, Rx helpful (Grandma’s warm
compress, erythro, sulfa, or quinolone drops or
ointment)
 EXCEPTION: “Hyperacute” variant from GC:
requires hospitalization b/o risk of keratitis and
perforation (GNC on Gm stain)
 Quinolone (ciprofloxacin) drops for contact lens-
associated infection (often Pseudomonas)
VIRAL CONJUNCTIVITIS
 Usually adenoviral
 Associated w/viral synd. or isolated
 Highly contagious
 Injection, watery or mucoserous d/c
 Pt. c/o unilateral burning, gritty/sandy sensation,
perhaps crusting overnight
 Inside lower lid may be bumpy looking
 Self-limited, 5 days to 3 wks.
 Topical antihistamines help sx
 EXCEPTION: EKC (epidemic keratoconjunctivitis)
w/fb sensation, resist opening eyes; need urgent
referral to avoid vision loss
ALLERGIC CONJUNCTIVITIS
 Bilat. conj. Injection, watery d/c, itchy
 Typically a hx of allergy
 Looks a lot like viral
conjunctivitis
 May have chemosis
(conj. edema), worst in patients
allergic to cats
Treatment of Allergic Rhinitis
1 to 2 drops QID PRN for Ocuhist, Naphcon-A, Visine AC,
First line: OTC no more than 3 weeks generic
antihistamine/de
congestant drop

Second line (may be used individually or together in addition to first line


agent)
Mast cell 1 to 2 drops BID Patanol, Optivar, Elestat, Zaditor
stabilizer/anti-
histamine
AND/OR

NSAID ophthalmic 1 to 2 drops QID PRN Acular


drop
For severe cases (should be used on an ongoing basis with first and second line agents
used in addition for symptomatic relief)
Mast cell stabilizer/ 1 to 2 drops QID Alomide, cromolyn 4 percent
antihistamine ophthalmic generic, Opticrom,
Crolom

adapted from UpToDate


NON-ALLERGIC, NON-INFECTIOUS
CONJUNCTIVITIS
 Typical patients
 Sjogren’s
 Idiopathic dry eyes
 Post-trauma
 S/P foreign body
 Symptomatic Rx
 Drops: Hypotears, Refresh, Tears II,
generic artificial tears/methyl cellulose
 Ointment: Lacrilube, Refresh PM, generic
CORNEAL ABRAISION
HISTORY OF TRAUMA
(none typically with keratitis)

Penlight exam
shows linear defect.

Fluorescein avidly stains


basement membrane.
Staining confirms linear
corneal damage.
SUBCONJUNCTIVAL HEMORRHAGE

History: Usually spontaeous,


on awakening.

Penlight Exam: Limbus is spared, unlike scleritis/episcleritis.

Treatment: None necessary (or possible).


CONTACT LENS OVERUSE
 MUST exclude corneal
infiltrate (spots)
 If absent, can Rx
anti-Pseudomonal
drops or ointment (ofloxacin, ciprofloxacin,
tobramycin)
(NOT sulfa or erythro) DO NOT PATCH.
 Recheck in 24 hrs or less.
 Corneal infiltrate can be devastating and
requires emergent referral.
EYELID LESIONS
 BLEPHARITIS Rx Grandma’s warm compress,
Inflammatory, can result baby shampoo
in chalazion or stye. Rx seborrhea or rosacea
if present
 CHALAZION
Chronic inflammatory lesion of tear gland
Rx soaks, NO antibiotics
Refer if persists more than a few weeks
Can be confused w/carcinomas
 HORDEOLUM (stye)
Purulent inflammation of lid, sterile or
bacterial (usually Staph. spp.)
Rx Grandma’s warm compress, antibiotic
if there is cellulitis.
Internal Refer if not resolved in 1 -2 weeks
External
WHAT SYMPTOMS REQUIRE
IMMEDIATE REFERRAL of RED EYE?

1. Unilateral red eye with N/V


2. Severe ocular pain
3. Loss of visual acuity
WHAT CONDITIONS REQUIRE
IMMEDIATE REFERRAL OF RED EYE?
 Keratitis (infection of cornea)
 Hyphema (blood in anterior chamber)
 Hypopyon (pus in anterior chamber)
 Acute glaucoma
 Penetrating trauma
Thank you for watching.

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