Plan of Dissertation

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PLAN OF DISSERTATION

Priya Puri M.Phil Trainee, 2nd Year (2011-2013) Department of Clinical Psychology

Dissertation Guide: Sri. Prasanta Kr. Roy, Assistant professor, Department of Clinical Psychology

Dissertation Co-guide: Dr. Partha Sarthy Biswas, Assistant professor, Department of Psychiatry.

Institute of Psychiatry, Kolkata

Dynamics and Neurocognitive Correlates in


Borderline Personality Disorder-

A Comparative Study

INTRODUCTION
The essential feature of Borderline Personality Disorder is a pervasive pattern of instability of interpersonal relationships, selfimage, and affects, and marked impulsivity that begins by early adulthood and is present in a variety of contexts (APA, 2000). Individuals with BPD experience emotional ups and downs, and are known to be unstable and especially angry.

REVIEW OF LITERATURE
Previous research suggests that BPD protocols contained more Rorschach scores indicating separation conflicts, as compared with other groups (Coonerty, 1986). Literature also suggests a genuine deficit of response inhibition in patients with BPD (Rentrop et al, 2008). Studies reveal that the parents of individuals with BPD have been described by offspring as negative; uncaring and over-controlling;

unempathetic (Fruzzetti, 2005; Johnson, 2006).

REVIEW OF LITERATURE (Contd...)


No Indian studies could be found on the dynamics and neuropsychological correlates of Borderline Personality Disorder. Since there is little work on given problem in India, it is important shed light on the dynamics and neurocognitive correlates in Borderline Personality Disorder in the Indian context, and thus the present study intends to be conducted.

METHODS
Study design: The present study is a cross-sectional comparative study based on quasi-experimental design. It will be based on purposive sampling. Aims: The aim of the study is to see the dynamics and neurocognitive correlates of individuals with Borderline Personality Disorder.

METHODS (Contd...)
Objectives:

To see the capacity for control associated with Borderline


Personality Disorder. To see the emotional regulation associated with Borderline Personality Disorder. To see the self and interpersonal perception associated with Borderline Personality Disorder. To see the information processing associated with Borderline Personality Disorder.

METHODS (Contd...)
Objectives (Contd...): To see the perception of parenting style associated with Borderline Personality Disorder. To see Impulsivity associated with Borderline Personality Disorder. To see the response inhibition associated with Borderline

Personality Disorder.
To see the feedback utilization associated with Borderline Personality Disorder.

METHODS (Contd...)
Sample: for the present study two groups will be taken which are as follows: Study group: it will consist of 30 individuals, males and females between the ages of 18-40years having Borderline Personality Disorder.

METHODS (Contd...)
Inclusion criteria for study group: Both males and females. Age limit 18-40 years. Right handed individuals. Individuals diagnosed with Borderline Personality Disorder (as per DSM-IV-TR criteria.)

Co-operative for the study


Individuals who give consent for the study

METHODS (Contd...)
Exclusion criteria for study group: Individuals having comorbid substance abuse/dependence (except nicotine dependence)

Individuals having a history of psychosis.


Individuals having a history of Bipolar Affective Disorder. Individuals having any chronic or acute physical illness. Individuals having any developmental abnormality. Individuals whose parents are dead, or separated before individuals 18 years of age. Individuals brought up by a single parent

METHODS (Contd...)
Sample (Contd...): Control group: it will consist of 30 individuals (males and females), matched in terms of age, gender, education and socioeconomic status, having no Axis I or Axis II diagnosis.

METHODS (Contd...)
Inclusion criteria for control group: Both males and females (age, sex, education and socio-economic status matched with the test group). Age limit 18-40 years. Right handed individuals. Co-operative for the study

Individuals who give consent for the study.

METHODS (Contd...)
Exclusion criteria for control group:

Individuals having substance abuse/dependence.


Individuals having a history of psychosis. Individuals having an Axis I or Axis II diagnosis. Individuals having any chronic or acute physical illness. Individuals having any developmental abnormality. Individuals whose parents are dead, or separated before individuals 18 years of age. Individuals brought up by a single parent

METHODS (Contd...)
Tools: Semi-structured Socio-demographic and clinical data sheet. Edinburgh Handedness Inventory (Oldfield, 1971).

General Health Questionnaire-12 (Goldberg & Williams, 1988)


Mini International Neuropsychiatric Interview (Sheehan et al., 1998) The Iowa Personality Disorder Screen (Langbehn et al., 1999)

METHODS (Contd...)
Tools (Contd...) International Personality Disorder Examination (Loranger et al, 1994; WHO, 1995)

Emotional Stroop test (Williams et al., 1996)


IOWA gambling task (Bechara et al, 1994) Parental Authority Questionnaire (Buri, 1991) Rorschach Inkblot Method (Exner, 2003)

METHODS (Contd...)
Procedure: For Study group: Individuals diagnosed as having Borderline Personality Disorder

by an expert psychiatrist, of Psychiatry outdoor, following DSMIV-TR criteria will be chosen. After establishment of adequate rapport and after obtaining

consent

from

the

participants,

Semi-structured

Socio-

demographic and clinical data sheet will be administered

METHODS (Contd...)
Procedure, for study group (contd...): Then, the Edinburgh Handedness Inventory shall be

administered and individuals who are right handed will be retained in the study. Following this the Mini International Neuropsychiatric Interview (M.I.N.I) shall be administered. Individuals who do not score on

any of the domains of M.I.N.I. shall be retained in the study


They will be administered International Personality Disorder Examination (IPDE).

METHODS (Contd...)
Procedure, for study group (contd...): If the individuals score is as per that stated by the manual for Borderline Personality Disorder, and if he does not qualify for any other personality disorder, further testing shall continue. Following this, the Emotional Stroop Test shall be administered, followed by IOWA gambling task, Parental Authority

Questionnaire (for both father and mother), and Rorschach


Inkblot Method.

METHODS (Contd...)
Procedure (Contd):

For Control group:


After establishment of adequate rapport and after obtaining consent from the participants, Semi-structured Socio-demographic and

clinical data sheet will be administered


Then the Edinburgh Handedness Inventory shall be administered and individuals who are right handed will be retained in the study.

Then GHQ-12 shall be administered to them and individuals who


obtained a score of below 2 on GHQ-12 shall be retained in the study.

METHODS (Contd...)
Procedure, for control group (contd...): This will be followed by the Iowa Personality Disorder Screen and Individuals who obtain a score of below 4 shall be retained in the study. Following this, the Emotional Stroop Test shall be administered, followed by IOWA gambling task, Parental Authority Questionnaire

(for both father and mother), and Rorschach Inkblot Method.

METHODS (Contd...)
Statistical analysis: Appropriate statistical analysis shall be done using Statistical Package for Social Sciences (SPSS-16).

REFERENCES
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental

disorders (4th ed., text rev.). Washington, DC: Author


Bechara, A., Damsio, A. R., Damsio, H., Anderson, S. W. (1994). "Insensitivity to future consequences following damage to human prefrontal cortex". Cognition 50 (1

3): 715
Buri, J. (1991). Parental Authority Questionnaire. Journal of Personality Assessment, 57(1), 110-119.

Coonerty, S. (1986). An exploration of separation-individuation themes in the


borderline personality disorder. Journal of Personality Assessment, 50, 501511.

REFERENCES (Contd...)
Exner, J.E. (2003).The Rorschach: Acomprehensive system (4thed.). New York:

JohnWiley.
Fruzzetti A.E, Shenk C, Hoffman PD. (2005) Family interaction and the development of borderline personality disorder: a transactional model. Dev Psychopathol, 17, 1007103. Goldberg, D. & Williams, P. (1988) A users guide to the General Health Questionnaire. Slough: NFER-Nelson Johnson JG, Cohen P, Chen H, et al. (2006), Parenting behaviours associated with risk for offspring personality disorder during childhood. Arch Gen Psychiatry; 63; 579587

REFERENCES (Contd...)
Langbehn, D.R., Pfohl, B.M., Reynolds, S., Clark, L.A., Battaglia, M., Bellodi, L.,

Cadoret, R., Grove, W., Pilkonis, P., & Links, P. (1999). The Iowa Personality Disorder
Screen: Development and preliminary validation of a brief screening interview. Journal of Personality Disorders, 13, 75-89. Loranger, A. W., Sartorius, N., Andreoli, A., et al (1994) The International Personality Disorder Examination. Archives of General Psychiatry, 51, 215 -224 Oldfield, R. C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychololgia, 9, 97-113. Rentrop M, Backenstrass M, Jaentsch B, Kaiser S, Roth A, Unger J, Weisbrod M, Renneberg B., (2008). Response inhibition in borderline personality disorder: performance in a Go/Nogo task. Psychopathology. 41(1):50-7

REFERENCES (Contd...)
Sheehan D.V., Lecrubier Y., Sheehan KH, et al. (1998). "The Mini-International

Neuropsychiatric Interview (M.I.N.I.): the development and validation of a


structured diagnostic psychiatric interview for DSM-IV and ICD-10". Journal of Clinical Psychiatry 59 Suppl 20, 2233. Williams, J. M. G., Mathews, A., & MacLeod, C. (1996). The emotional Stroop task and psychopathology. Psychological Bulletin, 120, 324. World Health Organization (1995). International Personality Disorder Examination (IPDE). DSM IV module. Nederlandse bewerking: I.J. Duijsens, E.H.M. EurelingsBontekoe & R.F.W. Diekstra, Leiderdorp: Datec.

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