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    DS - Catapres

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    DOni Corleone
    Clonidine hydrochloride is a central-acting antihypertensive drug used as a second-line treatment for hypertension alone or with other drugs, and can also be administered epidurally to help manage severe pain; common adverse effects include dry mouth, sedation, dizziness, and hypotension, so blood pressure and heart rate should be closely monitored when using this drug. Nurses should assess blood pressure, weight, intake and output, and monitor for signs of depression when patients are taking clonidine hydrochloride.

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    DS - Catapres

    Uploaded by

    DOni Corleone
    138 views2 pages
    Clonidine hydrochloride is a central-acting antihypertensive drug used as a second-line treatment for hypertension alone or with other drugs, and can also be administered epidurally to help manage severe pain; common adverse effects include dry mouth, sedation, dizziness, and hypotension, so blood pressure and heart rate should be closely monitored when using this drug. Nurses should assess blood pressure, weight, intake and output, and monitor for signs of depression when patients are taking clonidine hydrochloride.

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    Clonidine hydrochloride is a central-acting antihypertensive drug used as a second-line treatment for hypertension alone or with other drugs, and can also be administered epidurally to help manage severe pain; common adverse effects include dry mouth, sedation, dizziness, and hypotension, so blood pressure and heart rate should be closely monitored when using this drug. Nurses should assess blood pressure, weight, intake and output, and monitor for signs of depression when patients are taking clonidine hydrochloride.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    138 views2 pages

    DS - Catapres

    Uploaded by

    DOni Corleone
    Clonidine hydrochloride is a central-acting antihypertensive drug used as a second-line treatment for hypertension alone or with other drugs, and can also be administered epidurally to help manage severe pain; common adverse effects include dry mouth, sedation, dizziness, and hypotension, so blood pressure and heart rate should be closely monitored when using this drug. Nurses should assess blood pressure, weight, intake and output, and monitor for signs of depression when patients are taking clonidine hydrochloride.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
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    Drug Name CLONIDINE HYDROCHLORIDE Catapres Classifications: cardiovascular agent; central-acting antihypertensive; analgesic

    Dosage & Route

    Action

    Indication Step 2 drug in stepped-care approach to treatment of hypertension, either alone or with diuretic or other antihypertensive agents. Epidural administration as adjunct therapy for severe pain.

    Adverse Effects CV: Hypotension (epidural), postural hypotension (mild), peripheral edema, ECG changes, tachycardia, bradycardia, flushing, rapid increase in BP with abrupt withdrawal. GI: Dry mouth, constipation, abdominal pain, pseudo-obstruction of large bowel, altered taste, nausea, vomiting, hepatitis, hyperbilirubinemia, weight gain (sodium retention). CNS: Drowsiness, sedation, dizziness, headache, fatigue, weakness, sluggishness, dyspnea, vivid dreams, nightmares, insomnia, behavior changes, agitation, hallucination, nervousness, restlessness, anxiety, mental depression. Skin: Rash, pruritus, thinning of hair, exacerbation of psoriasis; with transdermal patch: hyperpigmentation, recurrent herpes simplex, skin irritation, contact dermatitis, mild erythema. Special Senses: Dry eyes. Urogenital: Impotence, loss of libido.

    Contraindication Pregnancy (category C), lactation. Use of clonidine patch in polyarteritis nodosa, scleroderma, SLE

    Nursing Responsibility

    PO 75 mcg 1 tab SL Prn for BP >140


    Centrally acting antiadrenergic derivative. Stimulates alpha2-adrenergic receptors in CNS to inhibit sympathetic vasomotor centers. Central actions reduce plasma concentrations of norepinephrine. It decreases systolic and diastolic BP and heart rate. Orthostatic effects tend to be mild and occur infrequently. Also inhibits renin release from kidneys.

    Assessment & Drug Effects

    Monitor BP closely. Determine positional changes (supine, sitting, standing). With epidural administration, frequently monitor BP and HR. Hypotension is a common side effect that may require intervention. Monitor BP closely whenever a drug is added to or withdrawn from therapeutic regimen. Monitor I&O during period of dosage adjustment. Report change in I&O ratio or change in voiding pattern. Determine weight daily. Patients not receiving a concomitant diuretic agent may gain weight, particularly during first 3 or 4 d of therapy, because of marked sodium and water retention. Supervise closely patients with history of mental depression, as they may be subject to further depressive episodes.

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