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‭FRONT PAGE‬

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‭ACKNOWLEDMENT‬

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‭CERTIFICATE‬

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‭TOPIC‬

‭4‬
‭TOPIC‬

‭5‬
‭TABLE OF CONTENT‬

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‭INTRODUCTION‬

‭ uman immunodeficiency virus infection and acquired immune deficiency syndrome‬


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‭HIV/AIDS is a spectrum of conditions caused by infectious human immunodeficiency‬
‭virus. Following initial infection, a person may not notice any symptoms or may‬
‭experience a brief period of influenza like illness. Typically, this is followed by a‬
‭prolonged period with no symptoms. As the infection progresses, it interferes more with‬
‭the immune system, increasing the risk of common infections like tuberculosis ,as well‬
‭as the other opportunistic infections, and tumours that rarely affect people who have‬
‭working immune systems. These late symptoms of infection are referred to as AIDS.‬
‭This stage is often also associated with weight loss. HIV is spread primarily by‬
‭(including anal and oral sex), contaminated blood transfusion, hypodermic needle and‬
‭from mother to child during pregnancy, delivery, or breastfeeding. Some bodily fluids,‬
‭such as saliva and tears, do not transmit HIV. Methods of prevention include safe sex,‬
‭needle exchange programs, treating those who are infected, and male circumcision‬
‭Disease in a baby can often be prevented by giving both the mother and child‬
‭antiretroviral meditation. There is no cure or vaccine; however, antiretroviral treatment‬
‭can slow the course of the disease and may lead to a near-normal life expectancy.‬
‭Treatment is recommended as soon as the diagnosis is made. Without treatment, the‬
‭average survival time after infection is 11 years.‬

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‭SIGNS AND SYMPTOMS‬

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‭CAUSES OF AIDS‬
‭ he main causes of AIDS is a disorder of cell mediated immune system of the body. The‬
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‭disorder is characterised by a reduction in the number of helper.T Cells which stimulate‬
‭antibody production by B-cells. This results in the loss of natural defence against viral‬
‭infection. HIV is a retrovirus that infects the vital organs of the human immune system‬
‭.The virus progresses in the absence of antiretroviral therapy. The rate of virus‬
‭progression varies widely between individuals and depends on many factors(age of the‬
‭patient, body's ability to defend against HIV, access to health care, existence of‬
‭coexisting infections, the infected person's genetic inheritance, resistance to certain‬
‭strains of HIV.‬

‭ IV CAN BE TRANSMITTED BY -‬
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‭• Sexual transmission . It can happen when there is contact with infected sexual‬
‭secretions (rectal, genital or oral mucous membranes). This can happen while having‬
‭unprotected sex, including vaginal, oral and anal sex or sharing sex toys with someone‬
‭infected with HIV.‬

•‭ Perinatal transmission . The mother can pass the infection on to her child during‬
‭childbirth, pregnancy, and also through breastfeeding.‬

•‭ Blood transmission . The risk of transmitting HIV through blood transfusion is‬
‭nowadays extremely low in developed countries, thanks to meticulous screening and‬
‭precautions. Among drug users, sharing and reusing syringes contaminated with‬
‭HIV-infected blood is extremely hazardous.‬

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‭SCREENING TEST OF AIDS‬
‭ IDS patients generally have circulated antibodies which can be detected. In many‬
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‭countries. This test is done as a routine on the blood donor, screening may be harmful to‬
‭victims. Person found to be HIV positive are found to be depressed and suicidal and are‬
‭denied insurance, evicted from their homes and fired from their jobs only a small‬
‭minority of such person are likely to develop full brown AIDS. However, the infected‬
‭person may spread infection to others.‬

‭HIV can be diagnosed through blood or saliva testing. Available tests include:‬

‭•‬‭Antigen/antibody tests. These tests usually involve‬‭drawing blood from a‬


‭ ein. Antigens are substances on the HIV virus itself and are usually‬
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‭detectable — a positive test — in the blood within a few weeks after exposure‬
‭to HIV. Antibodies are produced by your immune system when it's exposed to‬
‭HIV. It can take weeks to months for antibodies to become detectable. The‬
‭combination antigen/antibody tests can take 2 to 6 weeks after exposure to‬
‭become positive.‬

•‭ Antibody tests. These tests look for antibodies to HIV in blood or saliva. Most‬
‭rapid HIV tests, including self-tests done at home, are antibody tests. Antibody‬
‭tests can take 3 to 12 weeks after you're exposed to become positive.‬

•‭ Nucleic acid tests (NATs). These tests look for the actual virus in your blood‬
‭(viral load). They also involve blood drawn from a vein. If you might have been‬
‭exposed to HIV within the past few weeks, your health care provider may‬
‭recommend NAT. NAT will be the first test to become positive after exposure to‬
‭HIV.‬

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‭Today ‘ELISA’ test is done to identify this pandemic disease [AIDS].‬

‭WESTERN BLOT TEST PROCESS‬

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‭TREATMENT FOR AIDS‬

‭ he most effective treatment for HIV is antiretroviral therapy (ART). This is a‬


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‭combination of several medicines that aims to control the amount of virus in your body.‬
‭Antiretroviral medicines slow the rate at which the virus grows. Taking these medicines‬
‭can reduce the amount of virus in your body and help you stay healthy.‬
‭It's important to take medicines exactly as the doctor tells . When treatment doesn't‬
‭work, it is often because HIV has become resistant to the medicine. This can happen if‬
‭we don't take our medicines correctly.‬

‭Other steps we can take include the following:‬

•‭ Keep your immune system strong by eating right, quitting smoking, and learning how‬
‭to avoid infection.‬

•‭ Monitor your CD4+ (white blood cells) counts to check the effect of the virus on your‬
‭immune system.‬

•‭ See a counsellor to help you handle the strong emotions and stress that can follow an‬
‭HIV diagnosis.‬

‭• Reduce stress so that you can better manage the HIV illness.‬

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‭PREVENTION OF AIDS/HIV‬

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‭CONCLUSION‬
‭ fter studying the causes and effects of AIDS from different views ,we conclude that it‬
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‭is a pandemic disease .It is mainly spread sexually and people of the age group of the‬
‭age group 25-45 years are the most affected group. There are some methods like‬
‭‘Antiviral Therapy’ and ‘Immune Stimulative Therapy’ which bring some hope that‬
‭even then no specific treatment has been found so far and mortality forms are virtually‬
‭100 % . So the only prevention is the test medicine care‬

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‭BIBLIOGRAPHY‬

‭ he following books were used for the above project –‬


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‭• Ncert textbook biology class XII‬
‭• Biology lab manual class 12‬

•‭ Ncert textbook class XI Also ,the following website were consulted for the relevant‬
‭information –‬
‭• www.wikipedia.org‬
‭• www.google.com‬
‭• www.icbse.com‬
‭• www.yahoo.com‬

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