Proxel 106

PROXEL™ 106 Antimicrobial TECHNICAL
INFORMATION BULLETIN
Table 1: Minimum Inhibitory Concentrations (MIC)

Micro-organism MIC (ppm)
Bacteria
Alcaligenes faecalis IMI 358536 10
Bacillus subtilis NCTC 10400 25
Burkholderia cepacia NCIMB 13694 25
Enterobacter cloacae CIP 104674 15
Escherichia coli IMI 362054 15
PROXEL 106 Antimicrobial is broad spectrum preservative Proteus vulgaris IMI 358534 12
for the protection of industrial water-based products against Pseudomonas aeruginosa IMI 358539 25
spoilage from bacteria, yeasts and fungi. It is a formulation Pseudomonas putida IMI 358533 25
of formaldehyde (HCOH) and a blend of 5-chloro-2-methyl- Pseudomonas stutzeri NCIMB 11359 8
4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazolin-3- Staphylococcus aureus NCIMB 9518 12
one (MIT).
Fungi
Applications Aspergillus niger ATCC 10575 625
The product is effective in polymer emulsions, paints, Penicillium funiculosum IMI 114933 25
adhesives, and pigment dispersions.
Yeasts
Preservative Properties Endomycopsis albicans NCYC 10231 95
This product is effective against a range of problem micro- Rhodotorula rubra NCTC 9449 50
organisms some of which are listed in Table 1. Please note Saccharomyces cerevisiae NCYC 87 50
that Minimum Inhibitory Concentrations (MIC) do not
represent effective in-use concentrations which should be
discussed with your local Arch representative.
PROXEL 106 Antimicrobial has a non-specific mode of

action which means that bacterial resistance is very unlikely
to occur. Detailed information on the mode of action is
available on request.
(continued on next page)
Arch Biocides
Table 2: Typical Physical Properties Technical Service

Composition An aqueous solution of formaldehyde Arch Biocides technical laboratories can assist with the
(HCOH) and a 3:1 blend of 5-chloro- above tests as part of your customer support programme.
2-methyl-4-isothiazolin-3-one (CMIT) Please contact your nearest Arch sales office to take
and 2-methyl-4-isothiazolin-3-one advantage of these customised services.
(MIT).
Risk Assessment & Management
Physical form Aqueous solution Arch professionals have a wide expertise in the fields of
Safety, Health and the Environment. Arch Biocides is
Viscosity at 20°C 6 mPa s committed to and uses this expertise in understanding the
suitability of PROXEL 106 Antimicrobial for specific
pH at 25°C 2-4 applications. Please contact your local Arch office should
you have questions in this area.
Flash point 56°C
Health And Safety
Storage stability Stable under normal conditions of The PROXEL 106 Antimicrobial Safety Data Sheet may be
storage. Avoid freezing. If frozen, supplied upon request. It should be read and understood by
allow to thaw and stir well before use. all supervisory personnel and employees before using this
product. If there is any doubt please contact your local
Compatibility Incompatible with alkalis and some Arch sales office for advice.
oxidising and reducing agents, e.g.
persalts, sulphites. Total Quality
Arch Biocides holds a number of ISO 9001 Quality
Density at 20°C 1.09 to 1.12 g/ml Management registrations covering our product range. The
scope of each registration is specific to the location or
entity named on the Registration Certificate and our
Amount To Use products are supplied to ISO 9001 Standards.
The concentration required to adequately preserve your
product depends on several factors. These include the
susceptibility of the system to microbiological degradation,
the extent to which microorganisms can gain access, the
species involved, pH, temperature, and length of time for
which protection is required.
Results of initial studies indicate that a concentration of

PROXEL 106 Antimicrobial in the range 0.1-0.3% should
be sufficient for most applications. Since the effective
concentration can be dependent on several factors we
recommend that compatibility/stability trials and
microbiological challenge testing should be carried out
before use.
(continued on next page)
Arch Biocides
Regulatory Information
The components of PROXEL 106 Antimicrobial are
incompliance with the following inventories:
EINECS (Europe)
TSCA (USA)
AICS (Australia)
ENCS (Japan)
DSL (Canada)
KECL (Korea)
PICCS (Philippines)
IECSC (China)
In many countries all the chemical components of a product

must be listed on the relevant “inventory” of chemical
substances before it can be supplied. However, listing on
an inventory does not necessarily permit all uses of a
product and it does not imply compliance with local or
regional regulations on biocidal products.
In many countries, use as a preservative against spoilage

(i.e. in-can preservation) is subject to additional legislation
which often requires a specific product registration.
Enquiries for further information and samples should be Some Arch® biocides may not be registered or registered
addressed to your local sales office. for only certain uses in your country.
Arch Biocides is a business unit of Arch Chemicals, Inc.
Any data relating to test organisms included in this

publication relates to standard laboratory test species and is
provided for information only. No claim of controlling
organisms in public health applications is made by the
inclusion of such data nor should it be implied.
No statement herein is intended as a representation or

warranty regarding PROXEL products or any other product
of Arch Chemicals, Inc.
PROXEL is a registered trademark of Arch UK Biocides Limited, a subsidiary of Arch Chemicals, Inc.
ARCH is a registered trademark, the property of Arch Chemicals, Inc.
SAFE HANDLING INFORMATION

Use biocides safely. Always read the label and product information before use. Refer to the Material Safety Data Sheet (MSDS)
available from Arch Chemicals, Inc. for information on the safe use, handling and disposal of this product.
Arch Biocides
Phone: (800) 523-7391 FAX: (866) 705-0465
5660 New Northside Drive, Suite 1100, Atlanta, GA 30328
© 2010 Arch Chemicals, Inc.
www.archbiocides.com
2-00580-R1

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PROXEL™ 106 Antimicrobial TECHNICAL

Table 1: Minimum Inhibitory Concentrations (MIC)

PROXEL 106 Antimicrobial has a non-specific mode of

(continued on next page)

Table 2: Typical Physical Properties Technical Service

Results of initial studies indicate that a concentration of

(continued on next page)

In many countries all the chemical components of a product

In many countries, use as a preservative against spoilage

Arch Biocides is a business unit of Arch Chemicals, Inc.

Any data relating to test organisms included in this

No statement herein is intended as a representation or

SAFE HANDLING INFORMATION

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