Pediatric IV Push Medications000 Final

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King Khalid University Hospital

Pharmacy Services Department

Pediatric IV Push Medications

1
Drug Diluents Maximum Conc. Time of Administration Comments &
King Khalid University Hospital Monitoring Parameters

Pharmacy Services DepartmentUndiluted


Adenosine 3mg/ml Rapid IV Push * Administer at peripheral IV site closest to
3 mg/ ml (2ml) over 1-2 seconds heart
* Follow with 5-10ml NS flush
*MP: ECG, HR, BP, RR
Atropine Undiluted 0.6mg/ml Rapid IV Push * Slow IV injection may result in
0.5mg & 0.6mg over 1-2 seconds paradoxical bradycardia
* MP: HR, secretions dryness
Aztreonam NS, D5W 66mg/ml Slow IV Push * Could also be given as intermittent
(Azactam®) over 3-5 min infusion over 20-60 min at a final conc. of
1g 20 mg/ml
*MP: Periodic liver function test
Bumetanide Undiluted 0.25mg/ml Slow IV Push MP: BP, serum electrolytes,
(Bumex®) 0.5mg over 1-2 min Renal function , Urine output
Calcium Chloride NS, D5W 100mg/ml for IV push Slow IV Push * Preferred way of administration for Ca
10% (100mg/ml) 20mg/ml for Infusion over 3-5 min replacement as infusion over 30-60 min.
Max.rate: 100mg/min * IV Push should be used only in case of
emergency situations.
* Administer over 10-20 sec only in cardiac
Calcium Gluconate NS, D5W 100mg/ml Slow IV Push arrest
10% (100mg/ml) 40mg/ml for Infusion over 3-5 min * Administer through central or large vein only
Max.rate: 100mg/min due to risk of extravasations.
* Risk of Bradycardia, Hypotension
*MP: HR, BP, Cardiac arrhythmia, Ca level

Cefazolin NS, D5W 100mg/ml Slow IV Push * Could also be given as intermittent infusion
(Ancef®) 1g 138mg/ml (if fluid- over 3-5 min over 10-60 min at a final conc. of 20 mg/ml
restricted patient)
(Claforan®) 1g NS, D5W 100mg/ml Slow IV Push *Rapid IVP may cause arrhythmia
150mg/ml (if fluid- over 3-5 min * Could also be given as intermittent infusion
restricted patient) over 15-30 min at a final conc. of 20-60mg/ml

Drug Diluents Maximum Conc. Time of Administration Comments &


Monitoring Parameters
Ceftazidime NS, D5W 180mg/ml Slow IV Push * Could also be given as intermittent infusion
(Fortaz®) over 3-5 min over 15-30 min at a final conc. of 40mg/ml
1g , 2g MP: renal, hepatic & hematologic function,
diarrhea
Ceftriaxone NS, D5W 40mg/ml Slow IV Push * Rapid IV injection may result in
(Rocephin®) over 3-5 min tachycardia,palpitations, diaphoresis &
1g 2 to 4 minutes has been restlessness
2 reported in pediatric * Could also be given as intermittent infusion
over 10-30 min at a final conc. of 40mg/ml
patients >11 years
King Khalid University Hospital

Pharmacy Services Department


F IV push medications should be administered only by a certified nurse.
F If any complication is noticed during administration, please contact the physician immediately
Prepared by: Manal Abou Elkheir, PharmD (PICU Clinical Pharmacist) Pager: 0949. Date: 8/2010
Reviewed by: Aljawharah Akoraishi, DPIC Clinical Pharmacist Date: 2017

Disclaimer
Although the author has been careful to recommend information that are in agreement with current standards and responsible literature, it
remains the responsibility of every practitioner to evaluate the appropriateness of a particular opinion in the context of the actual clinical
situation and with due consideration of any new developments in the field.
Please report any comment or concern to [email protected]

References:
1. Lexicomp online.
2. Taketomo CK et al. Pepiatric Dosage Handbook. Lexi-Comp’s Drug Reference Handbooks, 15th ed 2008-2009.
3. Hutchinson TA, Shahan DR & Anderson ML (Eds): DRUGDEX® System. MICROMEDEX, Inc., Grernwood Village, Colorado (9/2010).
4. Lawrence A. Trissel. Trissel's Handbook on Injection Drugs. 13th edition.
5. Phelps SJ. Pediatric Injectable Drugs, Teddy Bear book. 6th ed.
6. Package inserts.

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