Human Health and Disease Study Material

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Human Health & Disease: Study

Material
Overview:
Health: A state of physical, mental, and social well-being.
Disease: A disorder of structure or function in a human, often leading to symptoms and
signs.

Types of Diseases:
1. Infectious Diseases: Caused by pathogens (e.g., bacteria, viruses, fungi, protozoa).
2. Non-Infectious Diseases: Caused by genetic or environmental factors (e.g., diabetes,
cancer).

Pathogens and Their Diseases:


1. Bacteria: Tuberculosis, typhoid, cholera.
2. Viruses: AIDS (HIV), common cold, dengue.
3. Fungi: Ringworm.
4. Protozoa: Malaria, amoebiasis.
5. Helminths: Ascariasis, filariasis.

Immunity:
Innate Immunity: Present from birth, non-specific defense (e.g., skin, mucous membranes,
phagocytes).
Acquired Immunity: Specific defense acquired after infection/vaccination. Involves
lymphocytes.

Types of Acquired Immunity:


Active Immunity: Long-lasting, acquired through exposure (natural or vaccination).
Passive Immunity: Short-term, transferred from mother to child or by antibody injections.

Cells of the Immune System:


B lymphocytes: Produce antibodies.
T lymphocytes: Help in cell-mediated immunity.
Diseases of the Immune System:
AIDS (Acquired Immunodeficiency Syndrome):
- Caused by HIV, which targets CD4 T cells.
- Mode of transmission: sexual contact, blood transfusion, sharing needles.
- Prevention: Safe sex practices, screening blood, avoiding needle sharing.

Cancer: Uncontrolled cell growth leading to tumors. Causes include carcinogens, genetics,
lifestyle. Treatments include surgery, chemotherapy, and radiation.

Lifestyle Diseases:
Diabetes: Due to insulin deficiency or resistance.
Hypertension: High blood pressure, can lead to heart disease.
Obesity: Leads to cardiovascular issues and diabetes.

Drugs and Alcohol Abuse:


Substance Abuse: Leads to addiction, liver damage (alcohol), lung disease (smoking), and
cardiovascular diseases.
Prevention: Awareness programs, counseling, family support.

Vaccination & Immunization:


Vaccines stimulate active immunity.
Common vaccines: Polio, DPT (diphtheria, pertussis, tetanus), Hepatitis B.

Previous Year Questions (PYQs):


 Explain the immune response in the human body. (3 marks)
 What is AIDS? How does HIV affect the immune system? (3 marks)
 What are carcinogens? How do they lead to cancer? (2 marks)
 Differentiate between active and passive immunity. (2 marks)
 Describe the life cycle of the malarial parasite in humans. (3 marks)

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