Glycolysis, Gluconeogenesis, PDH, KREBS & PPP Cycle 2

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sulin GLYCOGENOLYSIS GLYCOGENESIS

Epinephrine yflucagon

GLYCOLYSIS Glucose GLUCONEOGENISIS


Occurs in cytoplasm a occursin cytoplasm mitochondria

nefgatiif.pe AH
a o pyruvate Glucose 6-P
I
PENTOSE PHOSPHATE
PATHWAY
Fructose 6-P
r
Ñ
appt
Affffffy Fructose 1,6-bP Fructose 2,6-bP

Dihydroxyacetone-P Dihydroxyacetone-P
2
7

Glyceraldehyde 3-P
INADI
2 NADH
1,3-bisphosphoglycerate (2)
LADP

26 4
3-phosphoglycerate (2)

2-phosphoglycerate (2)

2H20
Phosphoenolpyruvate (2)
r
ADP

4
26Pyruvate (2)
i a
riff ADP
No Oxygen present?
r Ethanol Lactate
u L Oxaloacetate (2)
ALCOHOL LACTIC ACID
fromCoricycle
FERMENTATION FERMENTATION
Pyruvate Pyruvate

2102 Oxygen present? mitochondria


Acetaldehyde 2nA
2N PDH COMPLEX

Finian
FMLN
temp
Yun
Ethanol Lactate EKREBS CYCLE
CORI CYCLE
GLYCOGENOLYSIS GLYCOGENESIS

GLYCOLYSIS Glucose GLUCONEOGENISIS


say
Glucose 6-P
army I
practice PENTOSE PHOSPHATE
as PATHWAY
the Fructose 6-P
products If_ r

FIT
Fructose 1,6-bP
00ft
Fructose 2,6-bP

Dihydroxyacetone-P
deem Dihydroxyacetone-P
a onto
7

Glyceraldehyde 3-P
demand
town
1,3-bisphosphoglycerate am
(2)

if
3-phosphoglycerate (2)

Madame
2-phosphoglycerate (2)

essence
Phosphoenolpyruvate (2)
stackoverflow.ir

Pyruvate (2)

Earth
rare
Macro

Ethanol
No Oxygen present? Lactateit Oxaloacetate
see (2)
r u
ALCOHOL LACTIC ACID
FERMENTATION FERMENTATION

NAD
im
any n yAfMfggg
Oxygen present?

PDH COMPLEX
the
2N KREBS CYCLE

madman
CORI CYCLE
GLYCOGENOLYSIS GLYCOGENESIS

GLYCOLYSIS Glucose GLUCONEOGENISIS


Glucokinase Liver ÉÑ
Hexokinase glucose 6 phosphatase
ADP
Glucose 6-P
I
hexose
Phospho Phospho hexose PENTOSE PHOSPATE
isomerase isomerase Is PATHWAY
Fructose 6-P
r
Ph0
Yff ADP
Iff fructose 1,6 bisphosphatase
Fructose f2,6-bP
Fructose 1,6-bP

Dihydroxyacetone-P aldolase aldolase Dihydroxyacetone-P

triose phosphate friosephosphate


isomerase isomerase
Glyceraldehyde 3-P

glyceraldehydephosphate
INADA glyceraldehydephosphate
dehydrogenase NADH v
dehydrogenase
1,3-bisphosphoglycerate (2)

phosphoglycerate phosphoglycerate
LADPA
King
LDL kinase
3-phosphoglycerate (2)

phosphoglycerate phosphoglycerate
mutase mutase
2-phosphoglycerate (2)

enol
99,4 enolase
Phosphoenolpyruvate (2)

CLADP r
pyruvate
kiI fk
Pyruvate (2)
carbffykinase

dehisattogenase Pab se ADP


r No Oxygen present?
Ethanol Lactate
u Oxaloacetate (2)
ALCOHOL LACTIC ACID
fromCoricycle
FERMENTATION FERMENTATION

Oxygen present? to

PDH COMPLEX ma
T
go
KREBS CYCLE

as
CORI CYCLE
GLYCOGENOLYSIS GLYCOGENESIS

GLYCOLYSIS Glucose GLUCONEOGENISIS

Glucose 6-P
I
PENTOSE PHOSPHATE
practice PATHWAY
the Fructose 6-P
r
enzymes
Fructose 1,6-bP Fructose
Ink2,6-bP

Dihydroxyacetone-P Dihydroxyacetone-P

Glyceraldehyde 3-P

1,3-bisphosphoglycerate (2)

3-phosphoglycerate (2)

2-phosphoglycerate (2)

Phosphoenolpyruvate (2)
r

Pyruvate (2)

see
r NoEthanol
ALCOHOL
Oxygen present? Lactate
u
LACTIC from
ACIDCoricycle
I Oxaloacetate (2)

FERMENTATION FERMENTATION

also
Oxygen present?
PDH COMPLEX
No
no
KREBS CYCLE
CORI CYCLE
L AcetylCoA
PDH CYCLE

Nose
occurs inmitochondriamatrix
aka pyruvatedecarboxylation
oxidativedecarboxylation
aerobic decarboxylation

Pyruvate El Pyruvate
DE Yase furghpified
mm
PDHcycle
OF
CoA sus EL poicacid CoASH

Acetyl-CoA
irreversiblestep
NAFE DE L
Acetyl-CoA
NAH

NADHY Oxaloacetate

tumor
after

L-malate
sore
n KREBS CYCLE
dado
y

Fumarate
a soCitrate

iiiiiii.is
f
FAD
KREBS CYCLE
CitrateIskrebssthfngffbihate.frMakingoxaloacetate

sad
Succinate IEess

Thin day
Isocitrate

Succinyl-CoA
Bor
CO

α -ketoglutarate
MATTE
NADH
NADH
2
L AcetylCoA
PDH CYCLE
mmmm
footenette mum
occurs inmitochondriamatrix
aka pyruvatedecarboxylation
oxidativedecarboxylation
aerobic decarboxylation
HE.rs

Pyruvate El Pyruvate
C
DE Yase furghpified

OF
EL poicacid SH
CoA
CoA sus Iifdhfiidd.info ask.ie
Acetyl-CoA
NAFE DE L
Acetyl-CoA
NAH

Oxaloacetate

tumor
0rem
L-malate
sore
n
IT

KREBS CYCLE
dado
y

Fumarate
ae
so
Citrate

KREBS CYCLE

sad
Succinate
b

day
Isocitrate
e

Succinyl-CoA
t
Bor
shirt

-ketoglutarate
MATTE deferens
PDH FCYCLEFor
L AcetylCoA

occurs inmitochondriamatrix
aka pyruvatedecarboxylation
oxidativedecarboxylation

MMM
aerobic decarboxylation
seasons

Pyruvate El Pyruvate
DE Yase furghpified

fY
OF
CoA sus EL ooffffi poicacid CoASH
hitrogenase
Acetyl-CoA
irreversiblestep
NAFE DE L
Acetyl-CoA
NAH

NAHM Oxaloacetate

tumor
THE'genase th
L-malate
sore
n KREBS CYCLE
Citratesynthase
fumarase dado
y

Fumarate
a soCitrate

FAH
ffnifjaimh.fi KREBS CYCLE aconitase
succinate
ehydrogenase
EI.fi r

sad
Succinate in
Tie
SuccinylCoA
day
Isocitrate

Synthetase
Succinyl-CoA fighting isocitrate
Bor dehydrogenase

Ketoglutarate CO
dehydro -ketoglutarate
f MATTE
NADH
L AcetylCoA
PDH CYCLE

aforested
occurs inmitochondriamatrix
aka pyruvatedecarboxylation
oxidativedecarboxylation
aerobic decarboxylation

Pyruvate El DE Yase
MMM furghpified
Pyruvate

OF
CoA sus EL Rhapsody
poicacid CoASH

name
Acetyl-CoA
NAFE DE L
Acetyl-CoA
NAH
I

Oxaloacetate
It
L-malate
sore tumor
n KREBS CYCLE
dado The
y

Fumarate
a so
Citrate

T KREBS CYCLE 5

sad
Succinate

day
Isocitrate

Succinyl-CoA
Bor a
-ketoglutarate
MATTE
PENTOSE PHOSPHATE
PATHWAY
A
Glucose 6-P

Tm Oxidative
(irreversible)
6- phosphogluconate

Ribulose 5-P

Ribose 5-P Nucleotide synthesis

Nonoxidative
Fructose 6-P (reversible)

GM
PENTOSE PHOSPHATE
Pr
A
PATHWAY
Glucose 6-P
Its
deserted
Tm Oxidative

ddofi
(irreversible)
6- phosphogluconate

szgzgjf.se
Ribulose 5-P

Ribose 5-P Nucleotide synthesis

Nonoxidative
Fructose 6-P (reversible)

GM
PENTOSE PHOSPHATE
PATHWAY
A
Glucose 6-P

EE I
Tm Oxidative
(irreversible)
6- phosphogluconate
ate
I Ribulose 5-P

Ribose 5-P Nucleotide

Nonoxidative
Fructose 6-P (reversible)

GM
PENTOSE PHOSPHATE practice
PATHWAY Infymes
A
Glucose 6-P

Tm Oxidative
(irreversible)
ratelimiting
step
6- phosphogluconate

v
Ribulose 5-P

v Nucleotide synthesis
Ribose 5-P
Nonoxidative
Fructose 6-P (reversible)

GM

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