MINISTERUL EDUCAȚIEI NAȚIONALE ȘI CERCETĂRII ȘTIINȚIFICE

Str. Universității nr.16, 700115, Iași, România

www.umfiasi.ro

SYLLABUS

1. Programme Details
1.1. GRIGORE T. POPA UNIVERSITY OF MEDICINE AND PHARMACY IASI
1.2. FACULTY: MEDICINE / DEPARTMENT: MEDICALE I
1.3. DISCIPLINE: GASTROENTEROLOGY
1.4. FIELD of STUDY: MEDICINE
1.5. STUDY CYCLE: BACHELOR
1.6. PROGRAMME of STUDY: Medicine - English

2. Discipline Details
2.1. Name of the Discipline: GASTROENTEROLOGY
2.2. Teaching staff in charge with lectures:Sef lucr. Anton Carmen,
2.3. Teaching staff in charge with seminar activities: Sef lucr. Anton Carmen, Sef lucr. Ciortescu Irina,
Sef. Lucr. Mitrica Dana Elena, Asistent univ. Timofte Oana, Asistent univ. Stoica Oana-Cristina,
Asistent univ. Balan Gheorghe, Asistent univ. Cuciureanu Tudor
Hourly payment: Sef. Lucr. Girleanu Irina, Asistent univ. Chiriac Andrei-Stefan, Asistent univ.
Maxim Roxana, Research Assistant Muzica Cristina
2.4. Year V 2.5. Semester I/II 2.6. Type of E1/E2 2.7. Mandatory
evaluation Discipline
regimen

3. Overall Time Estimates (hours/semester of didactic activity)

3.1. Number of 15 Of which: 3.2. 5 3.3. seminar/ 10
hours per week lectures laboratory
3.4. Total hours 90 Of which: 3.5. 30 3.6. seminar/ 60
in the curriculum lectures laboratory
Distribution of time Hours
Study time using coursebook materials, bibliography and notes 20
Further study time in the libray, online and in the field 3
Preparation time for seminars / laboratories, homework, reports, portfolios and essays 10
Tutoring 2
Examinations 2
Other activities -

FACULTATEA DE MEDICINĂ
+40 232 301 615 tel / +40 232 301633 fax

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3.7. Total hours of individual study 35
3.8. Total hours / semester 125
3.9. Number of credits 13*
**ECTS within Internal Medicine

4. Prerequisites (where applicable)

4.1. curriculum Human anatomy and physiology
Neuroanatomy
Genetics
Microbiology
Immunology
Semiology
4.2. competences Measuring the blood pressure
Topographical localization of the organs
Localization of the arteries
Central and peripheral nervous system functions

5. Conditions (where applicable)

5.1. for lecture delivery Amphitheatre
5.2. for seminar / laboratory delivery In the wards, near the patient’s bed

6. Specific Competences Acquired

Professional 1. Evaluation of the patient with digestive symptoms
Competences 2. Evaluation of the patient with abnormal liver tests
(knowledge and skills) 3. Evaluation and treatment of patients with gastro-oesophageal reflux
disease
4. Evaluation and treatment of patients with esophageal motor disorders
5. Evaluation and treatment of patients with esophageal cancer
6. Evaluation and treatment of patients with gastric ulcer
7. Evaluation and treatment of patientss with duodenal ulcer
8. Evaluation and treatment of patients with gastric cancer
9. Evaluation and treatment of patients with malabsorption
10. Evaluation and treatment of patients with celiac disease
11. Evaluation and treatment of patients with benign and malignant tumors of
the gut
12. Evaluation and treatment of patients with ulcerative colitis
13. Evaluation and treatment of patients with Crohn's disease
14. Evaluation and treatment of patients with irritable bowel syndrome
15. Evaluation and treatment of patients with colonic diverticula
16. Evaluation and treatment of patients with hemorrhoidal disease
17. Assessment and treatment of patients with benign colon tumors
18. Evaluation and treatment of patients with malignant colon tumors
19. Evaluation and treatment of patients with acute pancreatitis
20. Evaluation and treatment of patients with chronic pancreatitis
21. Evaluation and treatment of patients with pancreatic cancer
22. Evaluation and treatment of patients with chronic viral hepatitis
23. Evaluation and treatment of patients with chronic alcoholic hepatitis
24. Evaluation and treatment of patients with chronic autoimmune hepatitis
25. Evaluation and treatment of patients with chronic metabolic hepatitis
26. Evaluation and treatment of patients with liver cirrhosis
27. Evaluation and treatment of patients with benign liver tumors
28. Evaluation and treatment of patients with malignant liver tumors
29. Evaluation and treatment of patients with upper and lower
gastrointestinal bleeding.
30. Evaluation and treatment of patients with jaundice
31. Evaluation and treatment of patients with peritoneal pathology
32. Evaluation and treatment of patients with gallstones
33. Evaluation and treatment of patients with biliary pathology

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Transversal Competences • Learning the skills necessary to efficiently communicate with the patient
(roles, personal and • Establishing proper doctor-patient relationship
professional • Understanding interdisciplinarity (collaboration between different medical
development) specialties)
• Understanding accountability in terms of medical professional liability.
• Developing team working skills
• Knowing how to make presentations at scientific circles / student
congresses

7. Obiectives of the Discipline (related to the acquired competences)

7.1. General Obiective - Ability to note the full clinical history and disease history
- Performing a good clinical examination
- Ability establish a positive diagnosis / differential diagnosis
- Time management
- Teamwork, multidisciplinary collaboration
- Ethical behavior
- Understanding the issues and legal obligations regarding
medical care
7.2. Specific Obiectives 1. Knowledge of technical regulations for harvesting of organic
products.
2. Acute abdominal pain / acute abdomen
3. Establishing the characteristics of the pain(acute or chronic,
localization, intensity, aggravating factors or relation to meals).
4. Recommendation investigations
5. Ability to recognize and differentiate conditions such as acute
appendicitis, diverticulitis, acute pancreatitis, acute cholecystitis,
bowel obstruction, perforated ulcer, mesenteric ischemia and other
causes of acute abdomen

Chronic abdominal pain

6. knowledge of various causes of chronic abdominal pain
7. Knowledge of Rome and Manning criteria

Dyspepsia
8. knowledge of organic causes of dyspepsia and functional dyspepsia
9. Understanding the importance of "alarm signs"
10. ability to establish diagnosis and treatment strategy

Nausea and vomiting

11. Knowledge of the causes of vomiting, especially extraintestinal
causes (toxic, neurological, metabolic, etc.)

Dysphagia, heartburn, chest pain

12. The correlation of these symptoms with gastroesophageal reflux
disease, esophageal cancer, motility disorders of the esophagus
13. Recognition of alarm symptoms and applying the necessary
diagnostic explorations

Acute diarrhea
14. Assessment and management of patients with acute diarrheic
syndrome, knowledge of the infectious and inflammatory etiologies

Chronic diarrhea
15. Knowledge of the causes of chronic functional / organicdiarrhea
16. Selecting appropriate and necessary paraclinical diagnostic

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method

Constipation
17. Clinical evaluation of patient that presents constipation
17. Recognition of alarm symptoms
18. Knowledge of digestive and systemic diseases that may be
associated with constipation
19. Ability to identify depressive / anxious syndromes

Upper gastrointestinal bleeding

20. Identification of the source of bleeding and establishing its
severity
21. Time-effective diagnosis and treatment strategies
22. The distinction between variceal and non-varicealbleeding

Lower GI bleeding
23. Determination of the source and of the severityof bleeding
24. Making the differential diagnosis of common causes of anorectal
bleeding and severe diverticulitis, inflammatory bowel disease,
polyps, cancer
25. Knowledge of the causes of anemia and the diagnostic algorithm

Jaundice and cholestasis

26. Knowledge of bilirubin metabolism and the main biochemical tests
recommended
27. The main types of jaundice and differential diagnosis
28. Recognition of the stigmata of chronic liver disease

Anorexia and weight loss

29. Distinguish between appetite disorders with gastrointestinal
etiology and other disorders (psychiatric, malignant, metabolic,
endocrine, etc.)

Ascites
30. Performing the differential diagnosis of ascites
31. Knowledge of the pathogenesis of portal hypertension
32. Identify other causes of ascites: ovarian cancer, heart failure,
nephrotic syndrome, etc.

Intestinal obstruction and ileus

33. Recognition of intestinal obstruction and ileus
34. Differentiation from mesenteric ischemia
35. Choosing the appropriate laboratory investigations and treatment
proper recommendation ofmedical / surgical treatment
36. Perform DRE: method, signs.

FUNCTIONAL DISORDERS AND MOTILITY OF THE INTESTINAL TRACT

37. Acquiring knowledge of pharingoesophageal disorders, gastro-
intestinal, colonic and anorectal disorders
38. Knowing the significance of alarm symptoms
39. Competence in achieving an accurate and complete history
40. Competence in empathy and compassionate approach to patient
complaints

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DISORDERS IN THE OROPHARYNGEAL FIELD
41. Gaining in-depth knowledge of gastroesophageal reflux disease,
Barrett's esophagus and esophageal tumors, post caustic esophagitis,
drug-induced, infectious, post traumatic oesophageal
pathology,esophageal diverticulitis, foreign bodies impactations.
42. Knowledge of the indications and interpretation of imaging
examination used to evaluate swallowing disorders and 24 h PH-metry.

GASTRO-DUODENAL DISORDERS
43. Knowledge of the assessment and treatment of gastric
andduodenal ulcers
44. Addressing gastric and duodenal ulcer complications, including
bleeding, perforation and obstruction
45. approach to long-term complications that occur following surgery
for gastric ulcer and bariatric surgery
46. Addressing duodenal tumors

PANCREATIC DISEASES
47. Addressing acute and chronic pancreatitis
48. Establishing the correct diagnostic and therapeutic approach to
pancreatic tumors

BILIARY DISORDERS
49. Knowledge of the mechanisms for gallstone formation
50. Recognition of the signs and symptoms of complications of
gallstones:
- biliary colic
- acute cholecystitis
- cholangitis
- obstructive jaundice
51. Knowledge of the diagnosis and treatment of
- Sclerosing cholangitis
- Biliary tract tumors
- Tumors of the gallbladder
- Tumors of the ampulla of Vater.
52. Knowledge of the indications and complications of endoscopic and
radiologic treatment of biliary disorders

LIVER DISEASES
53. Recognition of the clinical, laboratory and biological
characteristics of:
- Acute hepatitis,
- Liver failure,
- Chronic hepatitis,
- Cirrhosis,
- Iron overload syndromes,
- Wilson's disease,
- Alpha1-antitrypsin deficiency,
- Intra and extra hepatic cholestasis,
- Cholangitis,
- Infiltrative liver disease,
- Vascular liver disease,
- Budd-Chiari syndrome,
- Portal vein thrombosis,
- Abscesses and liver tumors.

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54. Knowledge of prognostic scores used to assess acute hepatitis.
55. Differential diagnosis of impaired consciousness in alcoholic
patients and knowledge of the principles approach ethanol withdrawal
syndrome
56. diagnosis and management of viral hepatitis, knowledge on the
program of vaccination and preventive measures available
57. diagnosis and treatment of autoimmune liver disease, hepatic
steatosis and drug-induced hepatitis; knowledge of indications for liver
biopsy in these situations
58. Addressing liver disease associated with pregnancy
59. Knowledge of clinical characteristics, biological imaging and
histopathology of liver cirrhosis
60. Acquiring knowledge on addressing the complications of cirrhosis,
including
- Variceal hemorrhage,
- Portal-hypertensive gastropathy,
- Ascites,
- Spontaneous bacterial peritonitis,
- Hepato-renal syndrome,
- Hepatic encephalopathy,
- Bacterial infections
61. The correct evaluation of the nutrition of thecirrhotic patient
62. Knowledge of the indications for liver transplantation and scores
used to assess pre-transplant patients
63. Approach to the Patient with primary and secondary liver
neoplasm

GUT DISORDERS
64. Addressing malabsorption, especially in the context of celiac
disease
65. Addressing localized bacterial infections in the intestines as well
as parasitosis and tropical diseases such as Whipple's disease
66. Addressing bacterial overgrowth syndrome
67. Addressing intestinal tumors
68. approach of Crohn's disease and of short bowel syndrome

COLON DISORDERS
69. Knowledge of diagnostic and therapeutic approach to ulcerative
colitis and Crohn's disease and their complications and extra intestinal
manifestations
70. Addressing the nutrition of patients with ulcerative colitis and
Crohn's disease
71. Early diagnosis and therapeutic conduct of fulminant colitis

CHEMOTHERAPY AND POST RADIOTHERAPY ENTEROPATHY

72. Acquiring knowledge on the diagnostic and therapeutic conduct for
post radiotherapy enteropathy
73. Recognizingthe situations requiring intestinal resection and
administration of nutritional support
74. Knowledge of the effects of chemotherapy on the intestine,
especially in immunocompromised patients

ANORECTAL DISEASE
75. Acquiring knowledge on organic anorectal diseases (hemorrhoids,
anal fissures, abscesses, fistulas, ulcers solitary rectal, anal itching,

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 infections and tumors)

8. Contents
8.1. Lecture Teaching methods Comments

Lecture 1. Introductory lecture - Approach to the patient PPT 1,5 hours

with digestive symptomsThe particularities of paraclinical
investigations in gastroenterology
Lecture 2. Esophageal diseases. Gastroesophageal Reflux PPT 1,5 hours
Disease.Esophageal Motor Disorders. Esophageal cancer.
Lecture 3. Diseases of the stomach and duodenum. PPT 1,5 hours
Dyspeptic syndrome. Gastritis. Gastric and duodenal ulcer.
Lecture 4. Diseases of the stomach and duodenum. Gastric PPT 1,5 hours
cancer. Management of gastric resections. The implications
of H Pylori infection in gastroenterology
Lecture 5. Diseases and investigation of the small PPT 1,5 hours
intestine. Diarheea, malabsorbtion, celiac disease, benigne
tumors.
Lecture 6. Inflamatory bowel diseases – ulcerative colitis PPT 1,5 hours
Lecture 7. Inflamatory bowel diseases –Crohn’s disease PPT 1,5 hours
Lecture 8. Recto-colonic diseases. Irritable bowel PPT 1,5 hours
syndrome. Diverticulosis. Hemorrhoidal disease..
Lecture 9.Benign and malignant colon tumors PPT 1,5 hours
Lecture 10.Pancreatic diseases. Acute pancreatitis. Chronic PPT 1,5 hours
pancreatitis. pancreatic cancer
Lecture 11. Approach of the liver diseases. Hepatic PPT 1,5 hours
syndroms
Lecture 12. Chronic viral hepatitis PPT 1,5 hours

Lecture 13. Chronic viral hepatitis PPT 1,5 hours

Lecture 14.Chronic hepatitis: alcoholic hepatitis, PPT 1,5 hours
autoimmune hepatitis, metabolic hepatitis,drug-induced
hepatitis, non-alcoholic steatohepatitis.
Lecture 15.Liver cirrhosis PPT 1,5 hours
Lecture 16. Liver cirrhosis PPT 1,5 hours
Lecture 17. Liver cirrhosis PPT 1,5 hours
Lecture 18. Benign and malignant hepatic tumors PPT 1,5 hours
Lecture 19. Upper and lower gastrointestinal bleeding PPT 1,5 hours
Bibliography
1. Note de curs- Gastroenterologie. Trifan A, Stanciu C. Editura „Gr. T. Popa” UMF Iași 2017
2. Stanciu C A Guide to Clinical Examination, Editura Gr. T. Popa, Iaşi, 2002
3. Lectures-Syllabus : Update in diagnosis and treatment of gastrointestinal disorders. Carmen Rodica
Anton – Platforma e-learning UMF ,,Gr. T. Popa’’, UMF Iași 2018
4. Barbara Bates, Lynn S. Bickley (Revised by), Robert A. Hoekelman (Revised by) Guide to Physical
Examination and History Taking (Lippincott Williams and Wilkins), Hardcover (1999)
5. Macleod's Clinical Examination, 12 th edition: Churchill Livingstone, Elsevier 2009.
6. Harrison’s Principles of Internal Medicine – Editia XVI – traducere selectiva pentru examenul de
rezidentiat
7. Gastrointestinal diseases during pregnancy: what does the gastroenterologist need to know?

Catarina Frias Gomes, Mónica Sousa, Inês Lourenço, Diana Martins, Joana Torres, Annals of

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 Gastroenterology (2018)
8. Pregnancy and Luminal Gastrointestinal Disease Sumona Saha, Michael B. Wallace , Bashar A. Aqel ,
Keith D. Lindor , Kenneth R. Devault, 2016.
8.2. Seminar / Laboratory Teaching methods Comments

Seminar 1 + 2. Approach to the patient with Clinical case presentation 2 hours

digestive symptoms. Particularities of
gastroenterology laboratory investigations
Seminar 3 + 4. Esophageal pathology. Clinical case presentation 2 hours
Gastroesophageal reflux disease . Esophageal
motor disorders
Seminar 5 + 6. Esophageal pathology. Clinical case presentation 2 hours
Esophageal cancer. The pathology of gastric and
duodenal ulcer
Seminar 7 + 8. Duodenal ulcer. Gastric cancer Clinical case presentation 2 hours
Seminar 9 + 10. Small bowel pathology. Clinical case presentation 2 hours
Malabsorption. celiac disease
11 + 12 seminar. Small bowel pathology. Benign Clinical case presentation 2 hours
and malignant tumors. Inflammatory bowel
diseases. ulcerative colitis
13 + 14 seminar. Inflammatory bowel diseases. Clinical case presentation 2 hours
Crohn's disease. Recto-colonic pathology.
Irritable Bowel Syndrome
15 + 16 seminar. Recto-colonic pathology. Clinical case presentation 2 hours
Diverticulosis. hemorrhoidal disease
17 + 18 seminar. Recto-colonic pathology motor Clinical case presentation 2 hours
disorders. Benign tumors of the colon
19 + 20 seminar. Malignant tumors of the colon. Clinical case presentation 2 hours
The pathology of the pancreas. acute
pancreatitis
21 + 22 seminar. The pathology of the pancreas. Clinical case presentation 2 hours
Chronic pancreatitis. Pancreatic cancer.
23 + 24 seminar. Chronic viral hepatitis. Clinical case presentation 2 hours
Chronic-alcoholic hepatitis
25 + 26 seminar. Chronic hepatitis, autoimmune Clinical case presentation 2 hours
hepatitis. Metabolic hepatitis
27 + 28 seminar. Liver cirrhosis. Benign and Clinical case presentation 2 hours
malignant liver tumors
29 + 30 seminar. The upper and lower Clinical case presentation 2 hours
gastrointestinal bleeding. Jaundice. Pathology
of peritoneum. Gallbladder pathology
Bibliography
1. Note de curs- Gastroenterologie. Trifan A, Stanciu C. Editura „Gr. T. Popa” UMF Iași 2017
2. Lectures-Syllabus: Update in diagnosis and treatment of gastrointestinaldisorders,vol.1, Carmen
Rodica Anton – Platforma e-learning UMF ,,Gr. T. Popa’’, UMF Iași 2018
3. Note de Lecture – Noţiuni de gastroenterologie şi hepatologie pentru studenţi. Cijevschi C., Mihai
C, Editura „Gr. T. Popa” 2013
4. Stanciu C A Guide to Clinical Examination, Editura Gr. T. Popa, Iaşi, 2002
5. Barbara Bates, Lynn S. Bickley (Revised by), Robert A. Hoekelman (Revised by) Guide to Physical
Examination and History Taking (Lippincott Williams and Wilkins), Hardcover (1999)
6. Harrison’s Principles of Internal 17 th edition: Fauci, Braunwald, Kasper, Hauser, Longo, Jameson,
Loscalzo-2008

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 7. Macleod's Clinical Examination, 12 th edition: Churchill Livingstone, Elsevier 2009.
8. Cecil – Textbook of internal medicine WB Saunders, 2000.
9. Epstein IE. Cardiac auscultation, Butterworth Heinemann, 1991.
10. Swartz MH. Textbook of physical diagnosis – history and examination. WB Saunders Company, 2002.

9. Correlations between the contents of the discipline and the expectations of the
epistemic community, of profesional associations and of employers in the field
Knowledge and skills are set as objectives mentioned as such in teaching and curricula reviewed annually.
After analysis within the discipline, they are discussed and approved at the Bureau of Curriculum, in order
to harmonize with other disciplines. Throughout the period is assessed systematically as possible direct
correlation between content and expectations of the academic community, Nominees of the community,
professional associations and employers. As a primary goal, discipline aims to give students optimal
preconditions for the next years of study in the program Licence in Medicine in anticipation of successful
employment immediately after graduation in residency programs in Romania and other EU countries.

10. Evaluation
Type of activity 10.1. Evaluation criteria: 10.2. Methods of 10.3.
evaluation Percentage of
final grade
10.4. Lecture Grade for multiple choice test standardized 50%
multiple choice test
10.5. Seminar /
Average grade of ongoing ongoing evaluation 10%
Laboratory examinations
Grade for practical examination practical exam 40%
Minimum standard of performance: at least grade 5 to pass the discipline

Date:
01.10.2018

Signiture of Didactic Co-ordinator

Prof. Dr. Trifan Anca

Signiture of Department Director

Prof. Dr. Trifan Anca

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