SAFETY DATA SHEET Version 8.

2
Revision Date 14.02.2024
according to Regulation (EC) No. 1907/2006 Print Date 16.05.2024
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Magnesium chloride
Product Number : M8266
Brand : Sigma
REACH No. : 01-2119485597-19-XXXX
CAS-No. : 7786-30-3

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company :

1.4 Emergency telephone

Emergency Phone # : +(44)-870-8200418 (CHEMTREC (GB))

+(353)-19014670 (CHEMTREC Ireland)
001-803-017-9114 (CHEMTREC India)

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
2.2 Label elements
No hazard pictogram, no signal word, no hazard statement(s), no precautionary
statement(s) required

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.

Ecological information:

Sigma- M8266 Page 1 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
 The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Toxicological information:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.1 Substances
Formula : Cl2Mg
Molecular weight : 95,21 g/mol
CAS-No. : 7786-30-3
EC-No. : 232-094-6
No components need to be disclosed according to the applicable regulations.

SECTION 4: First aid measures

4.1 Description of first-aid measures
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling
unwell.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Sigma- M8266 Page 2 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
5.2 Special hazards arising from the substance or mixture
Hydrogen chloride gas
Magnesium oxide
Not combustible.
Ambient fire may liberate hazardous vapours.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger
area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry.

Store under inert gas. Hygroscopic.

Storage class
Storage class (TRGS 510): 13: Non Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

Sigma- M8266 Page 3 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Personal protective equipment

Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L

Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type P1
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.

Sigma- M8266 Page 4 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Physical state crystalline
b) Color white
c) Odor odorless
d) Melting Melting point/range: 714 °C
point/freezing point
e) Initial boiling point 1.412 °C
and boiling range
f) Flammability (solid, The product is not flammable.
gas)
g) Upper/lower No data available
flammability or
explosive limits
h) Flash point Not applicable
i) Autoignition > 404 °C
temperature - Regulation (EC) No. 440/2008, Annex, A.16
j) Decomposition No data available
temperature
k) pH No data available
l) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubility 468,7 g/l at 20 °C - soluble
n) Partition coefficient: Not applicable for inorganic substances
n-octanol/water
o) Vapor pressure No data available
p) Density 2,32 g/mL at 25 °C
Relative density No data available
q) Relative vapor No data available
density
r) Particle No data available
characteristics

s) Explosive properties No data available

t) Oxidizing properties none
9.2 Other safety information
No data available

Sigma- M8266 Page 5 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
SECTION 10: Stability and reactivity
10.1 Reactivity
No data available
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Violent reactions possible with:
acids

10.4 Conditions to avoid

When mixed with limited amount of water enough heat may be generated to cause
frothing. Exposure to moisture.
no information available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - female - > 5.000 mg/kg
(OECD Test Guideline 423)
Inhalation: No data available
LD50 Dermal - Rat - male and female - > 2.000 mg/kg
(OECD Test Guideline 402)
Skin corrosion/irritation
Skin - In vitro study
Result: No skin irritation - 15 min
(Human Skin Model Test)
Remarks: (for the hexahydrate)
The value is given in analogy to the following substances: Magnesium chloride
hexahydrateThe value is given in analogy to the following substances: magnesium chloride

Serious eye damage/eye irritation

Eyes - Rabbit
Result: No eye irritation - 72 h
(OECD Test Guideline 405)
Remarks: (for the hexahydrate)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative
(OECD Test Guideline 406)
Germ cell mutagenicity
Sigma- M8266 Page 6 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
 Test Type: Human
Test system: lymphocyte
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
Repeated dose toxicity - Rat - male and female - Oral - NOAEL (No observed adverse effect
level) - > 1.000 mg/kg

RTECS: OM2800000
Central nervous system depression, Vomiting, Diarrhea, Abdominal pain, To the best of our
knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.

SECTION 12: Ecological information

12.1 Toxicity
Toxicity to fish static test LC50 - Pimephales promelas (fathead minnow) - 2.119,3
mg/l - 96 h
(US-EPA)
Toxicity to daphnia static test LC50 - Daphnia magna (Water flea) - 548,4 mg/l - 48 h
and other aquatic Remarks: (ECHA)
invertebrates
Toxicity to algae Growth rate EC50 - Desmodesmus subspicatus (green algae) - > 100
mg/l - 72 h
(OECD Test Guideline 201)

Sigma- M8266 Page 7 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
 Toxicity to bacteria static test EC50 - activated sludge - > 900 mg/l - 3 h
(OECD Test Guideline 209)
Toxicity to daphnia semi-static test EC10 - Daphnia magna (Water flea) - 321 mg/l - 21
and other aquatic d
invertebrates(Chronic Remarks: (ECHA)
toxicity)
12.2 Persistence and degradability
The methods for determining the biological degradability are not applicable to inorganic
substances.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods
No data available

SECTION 14: Transport information

14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods

Sigma- M8266 Page 8 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user

Further information
Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out

Sigma- M8266 Page 9 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
SECTION 16: Other information
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods
by Inland Waterways; ADR - Agreement concerning the International Carriage of
Dangerous Goods by Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM -
American Society for the Testing of Materials; bw - Body weight; CMR - Carcinogen,
Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for
Standardisation; DSL - Domestic Substances List (Canada); ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS -
Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx -
Concentration associated with x% growth rate response; GHS - Globally Harmonized
System; GLP - Good Laboratory Practice; IARC - International Agency for Research on
Cancer; IATA - International Air Transport Association; IBC - International Code for the
Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half
maximal inhibitory concentration; ICAO - International Civil Aviation Organization;
IECSC - Inventory of Existing Chemical Substances in China; IMDG - International
Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial
Safety and Health Law (Japan); ISO - International Organisation for Standardization;
KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a
test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose);
MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. -
Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration;
NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading
Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic
Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution
Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines
Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure
Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and
Restriction of Chemicals; RID - Regulations concerning the International Carriage of
Dangerous Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS -
Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand
Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN
- United Nations; UNRTDG - United Nations Recommendations on the Transport of
Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative

Further information
The information is believed to be correct but is not exhaustive and will be used solely as
a guideline, which is based on current knowledge of the chemical substance or mixture
and is applicable to appropriate safety precautions for the product. It does not represent
any guarantee of the properties of the product. Sigma-Aldrich Corporation and its
Affiliates shall not be held liable for any damage resulting from handling or from contact
with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The branding on the header and/or footer of this document may temporarily not visually match
the product purchased as we transition our branding. However, all of the information in the
document regarding the product remains unchanged and matches the product ordered. For
further information please contact [email protected].
Sigma- M8266 Page 10 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada
Sigma- M8266 Page 11 of 11

The life science business of Merck operates as MilliporeSigma in the US and

Canada