Diml 023 Disease Pathology

Download as pdf or txt
Download as pdf or txt
You are on page 1of 4

GRETSA UNIVERSITY - THIKA

UNIVERSITY EXAMINATIONS
JANUARY – APRIL 2017 SEMESTER

DIPLOMA IN MEDICAL LABORATORY SCIENCE

COURSE CODE: DIML 023


COURSE TITLE: DISEASE PATHOLOGY

DATE: 6 APRIL 2017 TIME: 3.00 PM – 6.00 PM

INSTRUCTIONS TO CANDIDATES

1. SECTION A IS COMPULSORY.
2. SECTION B: ANSWER ANY OTHER THREE QUESTIONS.
3. DO NOT WRITE ANYTHING ON THIS QUESTION PAPER AS IT WILL BE AN EXAM
IRREGULARITY.
4. ALL ROUGH WORK SHOULD BE AT THE BACK OF YOUR ANSWER BOOKLET AND
CROSSED OUT.

Page 1 of 4
CAUTION: All exam rooms are under CCTV surveillance during the examination period.

SECTION A 40MKS

1. How does an increase in intracellular calcium mediate its damaging effects on cells?

A. Loss of cellular contents

B. Loss of energy dependant cellular functions

C. Lysis of the plasma membrane

D. Protein breakdown and DNA damage

2. A neoplasm that bears little resemblance to its original tissue source is said to be

A. Anaplastic

B. Dysplastic

C. Poorly differentiated

D. Well differentiated

3. Which of the following is a feature of necrosis?

A. Fragmentation of the cell

B. Inflammation of neighbouring cells

C. Plasma membrane intact

D. Reduced cell size

4. Which type of immunoglobulin is able to cross the placenta?

A. IgA

B. IgE

Page 2 of 4
C. IgG

D. IgM

5. Which cells are most affected by Type II hypersensitivity reactions?

A. Epitheloid

B. Haematopoietic

C. Immune

D. Nervous

6. Explain the three branches of pathology 6mks

7. State 5 types of fluid imbalance 5mks

8. Outline 5 Types of necrosis 5mks

9. Explain the meaning of the following terms 3mks

i. Pathogenesis

ii. Morphologic changes

iii. Etiology

10. Explain briefly cell repair 3mks

11. State 5 Cardinal signs of inflammation 5mks

12. State 3 Factors that influence wound healing 3mks

13. State 5 causes of cell Atrophy 5mks

Page 3 of 4
SECTION B 60MKS

1. a) Discuss 3 types of granuloma 12mks

b) Explain 4 mediators of inflammation 8mks

2. a) discuss briefly disease etiology 10mks

b) Briefly discuss the course of disease 10mks

3. a) Discuss 5 causes of cellular injury 10mks

b) Explain 5 ways in which cells adapts injury 10mks

4. a) Explain 6 Causes of chronic inflammation 12mks

b) Explain stages of cellular response to inflammation 8mks

Page 4 of 4

You might also like