Rewrite
Rewrite
Rewrite
HIV
WHAT IS HIV
The HIV human immunodeficiency virus is a virus that attacks cells that help
the body fight infection, making a person more vulnerable to other infections and
diseases. It is spread by contact with certain bodily fluids of a person with HIV, most
commonly during sex with a condom or sex without a condom HIV can lead to the
disease AIDS (acquired immunodeficiency syndrome). The human body can’t get rid
of HIV and no effective HIV cure exists. So, once you have HIV, you have it for life.
In addition, there are effective methods to prevent getting HIV through sex or drug
use, including pre- exposure prophylaxis (Prep) and post-exposure prophylaxis (PEP).
The human immunodeficiency viruses (HIV) are two species of Lentivirus (a
subgroup of retrovirus) that infect humans. Over time, they cause acquired
immunodeficiency syndrome (AIDS), a condition in which progressive failure of the
immune system allows life-threatening opportunistic infections and cancers to thrive.
The average survival time after infection with HIV is estimated to be 9 to 11 years. In
most cases, HIV is a sexually transmitted infection and occurs by contact with or
transfer of blood, pre-ejaculate, semen, and vaginal fluids. Non-sexual transmission
can occur from an infected mother to her infant during pregnancy, during childbirth by
exposure to her blood or vaginal fluid, and through breast milk. Within these bodily
fluids, HIV is present as both free virus particles and virus within infected the vital
immune cells in the human immune system, such as helper T cells (specifically CD4+
T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+
T cells through a number of mechanisms, including proptosis of abortively infected T
cells, apoptosis of uninfected bystander cells, direct viral killing of infected cells, and
killing of infected CD4+ T cells by CD8+ cytotoxic lymphocytes that recognize
infected cells. When CD4+ T cell numbers decline below a critical level, cell-
mediated immunity is lost, and the body becomes progressively more susceptible to
opportunistic infections, leading to the development of AIDS.
-Fever
-Headache
-Muscle aches and joint pain
-Rash
-Sore throat and painful mouth sores
-Swollen lymph glands, mainly on the neck
-Diarrhea
-Weight loss
-Cough
-Night sweats
- Persistent, unexplained fatigue
-Swollen lymph glands
-Oral yeast infection (thrush)
-Shingles (herpes zoster)
-Pneumonia
-Progression to AIDS
-Sweats
-Chills
-Persistent white spots or unusual lesions on your tongue or in your mouth
-Weakness
-Weight loss
These symptoms can be so mild that you might not even notice them. However, the
amount of virus in your bloodstream is quite high at this time. As a result, the
infection spreads more easily during primary infection than during the next stage.
Clinical latent infection (Chronic HIV) In this stage of infection, HIV is still present in
the body and in white blood cells. However, many people may not have any
symptoms or infections during this time. This stage can last for many years. Some
people develop more severe disease much sooner.
The more partners you have, the more likely you will catch HIV (STD). Having an
STD can increase your risk of getting HIV or spreading it to others and for people
who do not have HIV but who are at risk of getting HIV. To reduce the risk of getting
HIV through sex or drug use. And also, do not share your equipment with others
2. Ebola
WHAT IS EBOLA
Ebola, first appeared in 1976 also known as Ebola virus disease (EVD) and
Ebola haemorrhagic fever (EHF), is a viral haemorrhagic fever in humans and other
primates, caused by ebolaviruses. Symptoms typically start anywhere between two
days and three weeks after becoming infected with the virus. The disease kills
between 25% and 90% of those infected about 50% on average. Death is often due to
shock from fluid loss, and typically occurs between six and 16 days after the first
symptoms appear. Fruit bats are believed to be the normal carrier in nature; they are
able to spread the virus without being affected by it. Control of outbreaks requires
community engagement, including rapid detection, contact tracing of those exposed,
care for those infected, and proper disposal of the dead through cremation or burial.
After a person recovers from Ebola, their semen or breast milk may continue to carry
the virus for anywhere between several weeks to several months. Fruit bats are
believed to be the normal carrier in nature; they are able to spread the virus without
being affected by it. As the virus spreads through the body, it damages the immune
system and organs. Ultimately, it causes levels of blood-clotting cells to drop. This
leads to severe, uncontrollable bleeding. The disease was known as Ebola
haemorrhagic fever but is now referred to as Ebola virus.
3.Tuberculosis
WHAT IS TUBERCULOSIS
TB that spreads to other organs can also cause blood in urine and loss of kidney
function, if TB affects the kidneys back pain and stiffness, muscle spasms, and spinal
irregularity if TB affects the spine, nausea and vomiting, confusion, and loss of
consciousness, if TB spreads to the brain. These symptoms can have many different
causes, however, and are not always a sign of TB. Most TB infections affect the lungs,
which can cause a persistent cough that lasts more than 3 weeks and usually brings up
phlegm, which may be bloody, breathlessness that gradually gets worse. TB outside
the lungs less commonly, TB infections develop in areas outside the lungs, such as the
small glands that form part of the immune system (the lymph nodes), the bones and
joints, the digestive system, the bladder and reproductive system, and the brain and
nerves (the nervous system).
Symptoms can include:
-Persistent swollen glands
-Abdominal pain
-Pain and loss of movement in an affected bone or joint confusion
-Persistent headache
-Fist (seizures)
LATENT OR ACTIVE TB
In most healthy people, the immune system is able to destroy the bacteria that cause
TB. But in some cases, the bacteria infect the body but do not cause any symptoms
(latent TB), or the infection begins to cause symptoms within weeks, months or even
years (active TB). Up to 10% of people with latent TB eventually develop active TB
years after the initial infection. This usually happens either within the first year or two
of infection, or when the immune system is weakened for example, if someone is
having chemotherapy treatment for cancer.
-Latent TB Infection.
Many of those who are infected with TB do not develop overt disease. They
have no symptoms and their chest x-ray may be normal. The only manifestation of
this encounter may be reaction to the tuberculin skin test (TST) or interferon-gamma
release assay (IGRA). However, there is an ongoing risk that the latent infection may
escalate to active disease. The risk is increased by other illnesses such as HIV or
medications which compromise the immune system. To protect against this, the
United States employs a strategy of preventive therapy or treatment of latent TB
infection.
4. Diabetes
WHAT IS DIABETES
Diabetes mellitus, commonly known as diabetes, is a group of metabolic
disorders characterized by a high blood sugar level over a prolonged period of time. If
left untreated, diabetes can cause many health complications. Acute complications can
include diabetic ketoacidosis, hyperosmolar hyperglycaemic state, or death. Serious
long-term complications include cardiovascular disease, stroke, chronic kidney
disease, foot ulcers, damage to the nerves, damage to the eyes and cognitive
impairment. Diabetes is due to either the pancreas not producing enough insulin, or
the cells of the body not responding properly to the insulin produced. There are three
main types of diabetes mellitus.
-Type 1 diabetes is an autoimmune disease. The immune system attacks and destroys
cells in the pancreas, where insulin is made. It’s unclear what causes this attack.
About 10 percent of people with diabetes have this type.
-Type 2 diabetes occurs when your body becomes resistant to insulin, and sugar
builds up in your blood.
-Prediabetes occurs when your blood sugar is higher than normal, but it’s not high
enough for a diagnosis of type 2 diabetes.
SYMPTOMS IN MEN
In addition to the general symptoms of diabetes, men with diabetes may have a
decreased sex drive, erectile dysfunction (ED), and poor muscle strength.
SYMPTOMS IN WONEN
Women with diabetes can also have symptoms such as urinary tract infections,
yeast infections, and dry, itchy skin.
-Type 1 diabetes.
Symptoms of type 1 diabetes can include:
-Extreme hunger
-Increased thirst
-Unintentional weight loss
-Frequent urination
-Blurry vision
-Tiredness
-It may also result in mood changes.
-Type 2 diabetes.
Symptoms of type 2 diabetes can include:
-increased hunger
- increased thirst
-increased urination
- blurry vision tiredness
-sores that are slow to heal
-It may also cause recurring infections. This is because elevated glucose levels make it
harder for the body to heal.
- Gestational diabetes.
Most women with gestational diabetes don’t have any symptoms. The condition is
often detected during a routine blood sugar test or oral glucose tolerance test that is
usually performed between the 24th and 28th weeks of gestation. In rare cases, a
woman with gestational diabetes will also experience increased thirst or urination.
-Type 1 diabetes.
Doctors don’t know exactly what causes type 1 diabetes. For some reason, the
immune system mistakenly attacks and destroys insulin-producing beta cells in the
pancreas. Genes may play a role in some people. It’s also possible that a virus sets off
the immune system attack.
-Type 2 diabetes.
Type 2 diabetes stems from a combination of genetics and lifestyle factors. Being
overweight or obese increases your risk too. Carrying extra weight, especially in your
belly, makes your cells more resistant to the effects of insulin on your blood sugar.
This condition runs in families. Family members share genes that make them more
likely to get type 2 diabetes and to be overweight.
-Gestational diabetes.
Gestational diabetes is the result of hormonal changes during pregnancy. The placenta
produces hormones that make a pregnant woman’s cells less sensitive to the effects of
insulin. This can cause high blood sugar during pregnancy. Women who are
overweight when they get pregnant or who gain too much weight during their
pregnancy are more likely to get gestational diabetes. The bottom line is both genes
and environmental factors play a role in triggering diabetes.
-Type 2 diabetes.
Your risk for type 2 diabetes increases if you:
-Are overweight
-Are age 45 or older
-Have a parent or sibling with the condition
-Aren’t physically active
-Have had gestational diabetes
-Have prediabetes
-Have high blood pressure, high cholesterol, or high triglycerides
-Have African American, Hispanic or Latino American, Alaska Native, Pacific
Islander, American, Indian, or Asian American ancestry.
-Gestational diabetes.
Your risk for gestational diabetes increases if you:
-Are overweight
-Are over age 25
-Had gestational diabetes during a past pregnancy
-Have a given birth to a baby weighing more than 9 pounds
-Have a family history of type 2 diabetes
-Have polycystic ovary syndrome (PCOS)