Patho 3

QP CODE : 1027
Rajiv Gandhi University of Health Sciences, Karnataka

MBBS Phase – II (CBME) Degree Examination - 06-Feb-2023
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – PAPER II (RS-4)

Q.P. CODE: 1027
(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 10 = 20 Marks
1. A 55 year old male patient presented with retrosternal pain radiating to left arm, dyspnoea
and sweating of sudden onset. Patient is a known smoker for the last 20 years
a) What is the provisional diagnosis?
b) Write in detail about the morphological changes of the organ involved
c) Write the biochemical markers indicative of the condition
d) Mention the complications of the disease
2. A 60 year old man developed loss of weight, upper abdominal pain, anorexia and
hematemesis in the last three months. An endoscopy was done which revealed an
exophytic mass in the gastric region.
a) What is the probable diagnosis?
b) Discuss the etiopathogenesis
c) Describe in detail the morphology of the lesion
d) Describe the mode of spread
SHORT ESSAYS 8 x 5 = 40 Marks

3.1. Describe the etiology and morphology of chronic Pyelonephritis
4.2. Classify testicular tumours and write about the morphology of Seminoma
5.3. List the malignant tumours of thyroid and describe papillary carcinoma of thyroid
6. Discuss the stages in the evolution of Lobar pneumonia and list the complications
7. Etiology and morphological features of carcinoma cervix
8. Etiology and pathogenesis of pyogenic osteomyelitis
9. Discuss the etiology, serum markers and outcome of chronic active hepatitis
10. Types and morphology of Renal cell carcinoma
SHORT ANSWERS 10 x 3 = 30 Marks
11. Labelled microscopic diagram of Osteoclastoma
12. Write a note on Glioblastoma multiforme
13. Describe the morphology of Basal cell carcinoma of skin

14. Three important prognostic factors of breast carcinoma
15. Cardiac vegetations
16. Describe the morphology of pleomorphic adenoma
17. Describe the morphology of Bronchiectasis
18. List the types of Gall stone and write three complications
19. Renal complications of diabetes mellitus
20. Describe the morphology of Phyllodes tumour of breast
Page 1 of 3
QP CODE : 1027
Multiple Choice Questions 10 x 1 = 10 Marks
21 i) Ferruginous bodies are seen in
A. Silicosis
B. Byssinosis
C. Asbestosis
D. Bagassosis
21 ii) All of the following are true about Adult Polycystic kidney disease EXCEPT
A. Autosomal dominant inheritance
B. Hypertension is rare
C. Can be associated with cysts in liver, lungs and pancreas
D. Pyelonephritis common
21 iii) Lymphoid aggregates is seen in which parotid tumour

A. Pleomorphic adenoma
B. Warthins tumour
C. Adenoid cystic carcinoma
D. Mucoepidermoid carcinoma
21 iv) Anti-Gliadin antibodies are detected in

A. Tropical sprue
B. Whipples disease
C. Celiac disease
D. Intestinal Lymphoma
21 v) In cirrhosis of liver, collagen is laid down by

A. Hepatocytes
B. Hepatic stellate cells
C. Biliary epithelial cells
D. Kupffer cells
22 i) Which of the following is not a malignant tumour of germ cell origin

A. Mature teratoma
B. Choriocarcinoma
C. Dysgerminoma
D. Embryonal carcinoma
22 ii) Most common site for medulloblastoma is

A. Medulla
B. Cerebellum
C. Cerebrum
D. Spinal cord
22 iii) Histological hallmark of Paget’s disease of nipple is

A. Caseous necrosis
B. Infiltration of the epidermis by malignant cells
C. Atypical lobular hyperplasia
D. Desmoplasia
22 iv) MEN IIB syndrome includes all EXCEPT

A. Hyperparathyroidism
B. Marfanoid features
C. Medullary thyroid carcinoma
D. Pheochromocytoma
22 v) Bone tumor arising from diaphysis is

A. Ostogenic sarcoma
Page 2 of 3
QP CODE : 1027
B. Chondrosarcoma
C. Giant cell tumour
D. Ewing sarcoma
******
Page 3 of 3
QP CODE : 1027
MBBS Phase – II (CBME) Degree Examination - 25-Feb-2022

Q.P. CODE: 1027
1. 40 year police constable gives history of epigastric pain and it is relieved after eating
certain food, for the last six months. Now he is presenting with dark coloured stools.
a) What is your diagnosis?
b) Describe the etiology, pathogenesis and microscopic feature of this condition
c) Write its complications
2. 60 year female presented with right flank pain and weight loss with fatigue for 3 month
duration. Ultrasound scan shows renal mass in the upper pole measuring 4.3 x 4 cm. urine
microscopy of the patient shows plenty of RBCs.
b) Describe the pathogenesis and microscopic variants of the disease
c) Add a note on spread of this disease

3.1. Subacute bacterial endocarditis.
4.2. Osteosarcoma.
5.3. Bronchiectasis.
6. Carcinoma penis.
7. Endometrial hyperplasia.
8. Lobular carcinoma Breast.

9. Hashimotos thyroiditis.
10. Classify CNS tumors.
11. Classification of cirrhosis of liver
12. Microscopic picture of Malignant Melanoma.
13. Write three morphological features of urothelial carcinoma of urinary bladder

14. Psammoma bodies.
15. Pagets disease of Bone.
16. Barretts esophagus.
17. Gross features of Seminoma.
18. Microscopic picture of Pleomorphic adenoma of salivary gland.
19. Verocay bodies.
20. Linitis plastica.
Page 1 of 3
QP CODE : 1027
21 i) Struma ovarii means
A. Germ cell tumour of ovary
B. Ovarian malformation
C. Endometriosis of ovary
D. Krukenberg tumour
21 ii) Glomus tumor

A. Salivary gland tumour
B. Benign mesenchymal neoplasms in subungual region
C. Renal tumour
D. Ovarian tumour
21 iii) Gynecomastia
A. Enlargement of male breast
B. Abnormal breast in female
C. Fat necrosis of breast
D. Ectopic breast tissue
21 iv) Anchovy Sauce type of pus seen in

A. Lung abscess
B. Amoebic liver abscess
C. Brain abscess
D. Pancreatitis
21 v) Dukes staging is for

A. Carcinoma stomach
B. Carcinoma oesophagus
C. Carcinoma colon
D. Carcinoma pancreas
22 i) Aphthous ulcer seen in

A. Mouth
B. Skin
C. Stomach
D. Colon
22 ii) Ghon’s Focus seen in

A. Skin
B. Tongue
C. Brain
D. Sub pleural lung
22 iii) All are germ cell tumors EXCEPT

A. Dysgerminoma
B. Embryonal Carcinoma
C. Krukenberg Tumour
D. Teratoma
22 iv) Psammoma bodies seen in

A. Papillary carcinoma thyroid
B. Follicular carcinoma thyroid
C. Medullary carcinoma thyroid
D. Oncocytic carcinoma thyroid
22 v) Rodent ulcer means

A. Squamous cell carcinomatous ulcer
B. Basal cell carcinoma
Page 2 of 3
QP CODE : 1027
C. Gastric ulcer
D. Ulcerative colitis
******
Page 3 of 3
QP CODE : 1027
MBBS Phase – II (CBME) Degree Examination - 18-May-2023

Q.P. CODE: 1027
1. A 50 year male with history of chronic alcohol consumption, presented with distended
abdomen. Ultrasound scan show reduced size of liver
b) Describe the pathogenesis and progression of this condition
c) Complications of this condition
2. A chronic smoker with history of exertional dyspnoea and weight loss, died of road
accident. On autopsy his both lungs is voluminous with rib markings on its surface.
b) Describe its different types
c) What are its complications

3.1. Pathogenesis of Atherosclerosis.
4.2. Gross and microscopic features and Acute post infectious Glomerulo nephritis.
5.3. Enumerate etiology and types of cardiomyopathies.
6. Germ cell tumours of Testis.
7. Morphological types of carcinoma cervix.
8. Gross and microscopy of Hydatidiform mole.
9. Benign fibroepithelial neoplasms of Breast.
10. Pathogenesis of simple and multinodular goiter.

11. Berry aneurysm.
12. Malignant Nephrosclerosis.
13. Tumour markers of carcinoma breast.

14. Mention three types of renal stones.
15. Morphology of basal cell carcinoma.
16. Aneurysmal bone cyst.
17. Oligodendroglioma.
18. Microscopic picture of Adenomyosis.
19. Pleomorphic adenoma of salivary glands
20. Name three thyroid malignancies.
Page 1 of 3
QP CODE : 1027
21 i) Causes of Hypercalcemia
A. Graves disease
B. Primary hyper parathyroisism
C. Carcinoid
D. Medullary carcinoma
21 ii) Mucin seen in

A. Lobular carcinoma breast
B. Comedo carcinoma breast
C. Colloid carcinoma breast
D. Fibrocystic disease breast
21 iii) Granulomas seen in all EXCEPT

A. Tuberculosis
B. Crohn’s disease
C. Ulcerative colitis
D. Sarcoidosis
21 iv) Epulis is
A. Localised swelling of gums
B. Benign breast lesion
C. Benign skin tumour
D. Benign thyroid tumor
21 v) Desmoids is most likely to arises from

A. Ovary
B. Cervix
C. Scar
D. Endometrium
22 i) Marfans syndrome
A. Disorders of connective tissue
B. Disorders of thyroid
C. Disorders of calcium metabolism,
D. Vit-D deficiency
22 ii) Cryptorchidism
A. Hydrocele
B. Thyroid deficiency
C. Adrenal deficiency
D. Undescended testis
22 iii) Malignancy, most commonly arising from renal pelvis is

A. Renal cell carcinoma
B. Transitional cell carcinoma
C. Melanoma
D. Adeno carcinoma
22 iv) Osteoid seen in

A. Enchondroma
B. Osteogenic sarcoma
C. Osteoclastoma
D. Paget diseases of bone
22 v) Markers of Epithelial carcinoma

A. Desmin
B. Vimentin
Page 2 of 3
QP CODE : 1027
C. Cytokeratin
D. S-100
******
Page 3 of 3
MBBS (Phase - II) Degree Examination - DEC 2016
Pathology – Paper II (Revised Scheme)
Q.P. CODE: 1057
1. Classify ovarian tumors. Discuss tumors of germ cell origin.
2. Enumerate ulcerative lesions of intestine. Write differences between ulcerative colitis and
Crohn’s disease.

3. Grave’s disease
4. Transitional cell carcinoma-bladder
5. Small cell tumors of lung
6. Benign Prostatic Hyperplasia
7. Atheroma – pathogenesis
8. Pathology of Rheumatic Heart Disease
9. Kidney in Hypertension
10. Morphological types of TB lung
11. REAL classification of Non-Hodgkin’s lymphoma
12. Fibro-Lamellar carcinoma liver

13. Helicobacter pylori
14. Borderline tumors of ovary
15. Barret’s oesophagus
16. Pericarditis
17. Fallot’s tetrology
18. Wilm’s tumor
19. Gynaecomastia
20. Osteoid Osteoma
21. Peutz Jegher syndrome
22. Down’s syndrome
23. List Asbestos related diseases.
24. Aetiology of breast cancer
25. Carcinoma in situ
26. Prognostic markers in breast carcinoma
27. Leukoplakia
28. Neuroblastoma
*****
MBBS (Phase - II) Degree Examination - JUNE 2016
Pathology – Paper II (Revised Scheme)
Q.P. CODE: 1057
1. Define Emphysema. Discuss types of emphysema.
2. Define and classify cirrhosis. Discuss causes of micronodular cirrhosis.

3. Hashimoto’s thyroiditis
4. Gross and microscopy of Hepatocellular carcinoma
5. Pyogenic osteomyelitis
6. Pathogenesis of glomerulo-nephritis
7. Aetiology and pathology of carcinoma cervix
8. Serological markers of viral hepatitis
9. Dissecting aneurysm
10. Multinodular goiter
11. Hepatoblastoma
12. Pathology of Rheumatic Heart Disease

13. Sezary syndrome
14. KW lesion in kidney
15. Paget’s disease of breast
16. Nodular sclerosis Hodgkin’s lymphoma
17. Etiology of breast carcinoma
18. Staging of colon cancer
19. Microscopy in mixed tumor of parotid
20. Atherosclerosis – gross lesions
21. Meningioma – types
22. Pheochromocytoma
23. Renal cell carcinoma – microscopy
24. Serological markers in testicular tumors
25. Aetiology of skin cancer
26. Name the giant cell lesions of bone.
27. Acute pancreatitis – gross and microscopy
28. Non-small cell tumors of lung
*****
M.B.B.S. PHASE II Degree Examination – JUNE 2017

Pathology-Paper -II
(Revised SCHEME)
QP Code: 1057
Draw neat labeled diagrams wherever necessary
1. Classify testicular tumors. Discuss etiopathogenesis and morphological features of Seminoma.
Add a note on role of tumor markers in testicular tumors.
2. Define peptic ulcer. Discuss etiopathogenesis, morphology and complications of peptic ulcer
disease.

3. Microscopic assessment of myocardial infarction
4. Hashimoto thyroiditis
5. Bronchiectasis
6. Hodgkin lymphoma
7. Carcinoid tumor
8. Pathogenesis of acute pancreatitis
9. Cirrhosis of liver
10. Phylloides tumor
11. Osteoclastoma
12. Tabulate differences between tuberculous meningitis and pyogenic meningitis

13. Histopathologic variants of lung carcinoma
14. Complication of atheroma
15. Gross changes in systemic hypertensive heart disease
16. Aschoff bodies
17. Diagrammatically represent 4 forms of vegetative endocarditis
18. Cholelithiasis
19. Graphically represent serologic markers in acute hepatitis A
20. Hydatiform mole
21. High risk HPV (Human Papilloma Virus)
22. Enlist pre-malignant lesions of skin
23. Classify ovarian sex-cord stromal tumors
24. Basal cell carcinoma
25. Neuroblastoma
26. Endometrial hyperplasia
27. Enlist bone forming tumors
28. Microscopic findings in Glioblastoma multiforme
*****
MBBS (Phase - II) Degree Examination - DECEMBER 2015
Pathology – Paper II (Revised Scheme II)
Q.P. CODE: 1082

1. Write autopsy findings in a patient dying of Cirrhosis.
2. Classify bone tumors. Write about types, gross and microscopy of Osteosarcoma.

3. Trophoblastic tumors
4. Thyroid adenoma
5. Fibrocystic disease of breast
6. Acid peptic disease
7. Burkit’s lymphoma
8. Lab investigations in a case of Myocardial infarction
9. Asbestos induced lung diseases
10. Hashomoto’s thyroiditis
11. Leiomyoma sites, histological types, gross and microscopy
12. Sequelae of Rheumatic Heart disease

13. Libman – Sack’s endocarditis
14. Renal osteodystrophy
15. Renal lesions in Diabetes Mellitus
16. Sequelae of Hepatitis B infection
17. Cervical intraepithelial neoplasia
18. Ewing’s sarcoma
19. Phyllodes tumor
20. Immuno histochemistry and its role in diagnosis of Tumors – list four tumors.
21. Hyperbilirubinaemia
22. Flea bitten kidney
*****
Pathology – Paper II (RS2 & RS3 Scheme)
Q.P. CODE: 1082

1. Enumerate the different Ulcerative Lesions of Intestine. Describe the etiopathogenesis of
Inflammatory Bowel disease. Tabulate the differences between Crohn’s disease and Ulcerative
Colitis. (3+3+4 = 10 marks)
2. A 48 years old lady presented with Bleeding per Vagina. Per Speculum examination showed an
Ulceroproliferative growth involving the external os which bleeds on touch.
a) What is the most probable diagnosis and why?
b) What is the etiopathogenesis of this condition?
c) Add a note on screening method for this condition. (2+4+4 = 10 marks)

3. Vegetations of Heart
4. Kidney lesions in Diabetic Nephropathy
5. Phaeochromocytoma
6. Pathogenesis and morphology of Grave’s disease – Thyroid
7. Etiopathogenesis of Bronchial Asthma
8. Fibroadenoma – Breast
9. Rheumatoid Arthritis
10. Basal Cell Carcinoma
11. Meningioma
12. Ewing’s Sarcoma

13. Amoebic Liver Abscess – morphology
14. Components of Fallot’s Tetrology
15. Molluscum Contagiosum
16. Causes for Subarachnoid Haemorrhage
17. Microscopic features of Schwannoma
18. Paget’s disease of Bone
19. Krukenberg tumour
20. Prognostic factors in Breast Carcinoma
21. Lesions associated with H. Pylori
22. Pilomatrixoma
*****
MBBS (Phase - II) Degree Examination - Dec - 2017
Q.P. CODE: 1082

1. Define and classify Cirrhosis. Describe the morphological features and complications of Alcoholic
Liver disease.
2. Classify tumours of Breast. Discuss the etiopathogenesis and pathology of Infiltrating Duct
Carcinoma.

3. Features and complications of Fallot’s Tetralogy
4. Pathogenesis and complications of Bronchiectasis
5. Morphology of Pleomorphic Adenoma
6. Role of Helicobacter Pylori in Gastric Ulcer
7. Pathogenesis and morphology of Crohn’s disease
8. Adult Polycystic Kidney disease
9. Discuss in brief etiopathogenesis of Malignant Melanoma.
10. Carcinoid syndrome
12. Pathogenesis, morphology and radiological features of Osteoclastoma

13. Morphology of Cervical Intraepithelial Neoplasia
14. Gross and microscopic features of Dysgerminoma
15. Tubercular Osteomyelitis
16. Types of Renal Calculi
17. Zollinger-Ellison syndrome
18. Role of HbA1C estimation in Diabetes
19. Cryptorchidism
20. Causes of Hydronephrosis
21. Leukoplakia of Oral Cavity
22. Importance of Reid index
*****
Q.P. CODE: 1082

1. A 10 years old boy presented with history of Sore Throat followed by Migratory Poly-arthritic and
Subcutaneous Nodules.
a) What is your probable diagnosis?
b) Discuss the etiopathogenesis.
c) Mention the morphological features in the target organ.
2. Classify Bone tumours. Discuss the pathogenesis and morphological features of Osteosarcoma.

3. Morphology of different stages of Pneumonia
4. Write a brief note on Hodgkin’s Lymphoma.
5. Etiopathogenesis of Peptic Ulcer
6. Etiopathogenesis and pathology of Alcoholic Liver disease
7. Morphology of Rodent Ulcer
8. Pheochromocytoma
9. Gross and microscopic features of Multinodular Goitre
10. Light microscopy in Minimal change disease
11. Morphology of Seminoma
12. Schirrhous Carcinoma of Breast

13. Retinoblastoma
14. Types of Emphysema
15. Microscopic features of Wilm’s tumour
16. Cholelithiasis
17. Morphology of Amoebic Liver Abscess
18. Barrett’s Oesophagus
19. Causes of Splenomegaly
20. Meckel’s Diverticulum
22. Enumerate Cystic diseases of Kidney.
*****
Q.P. CODE: 1082

1. Classify Ovarian tumours. Describe the pathology of Papillary Serous Cyst-adenocarcinoma of
Ovary. (2+8)
2. A 10 year old boy developed Migratory Arthritis of Large Joints and features of Pancarditis, after 10
days, following episode of Pharyngitis.
b) Describe the etiopathogenesis of underlying disorder. (2+8)

3. Gastric Carcinoma
4. Alcoholic Liver disease
5. Bronchial Asthma
6. Germ Cell tumours of Ovary
7. Complications of Gall Stones
8. Thyrotoxicosis
9. Intestinal Amoebiasis
10. Lung Abscess
11. Premalignant Lesions of Squamous Cell Carcinoma of Skin
12. Pyogenic Meningitis

14. Medullary Carcinoma of Thyroid
15. Kidney changes in Malignant Hypertension
16. Classification of Hodgkin’s disease
17. Causes for Splenomegaly
19. Colloid Goitre
21. Leiomyoma – Uterus
22. Scar Endometriosis
*****
MBBS (Phase - II) Degree Examination - DECEMBER 2015
Q.P. CODE: 1082

1. Write autopsy findings in a patient dying of Cirrhosis.
2. Classify bone tumors. Write about types, gross and microscopy of Osteosarcoma.

3. Trophoblastic tumors
4. Thyroid adenoma
5. Fibrocystic disease of breast
6. Acid peptic disease
7. Burkit’s lymphoma
8. Lab investigations in a case of Myocardial infarction
9. Asbestos induced lung diseases
10. Hashomoto’s thyroiditis
11. Leiomyoma sites, histological types, gross and microscopy
12. Sequelae of Rheumatic Heart disease

13. Libman – Sack’s endocarditis
14. Renal osteodystrophy
15. Renal lesions in Diabetes Mellitus
16. Sequelae of Hepatitis B infection
17. Cervical intraepithelial neoplasia
18. Ewing’s sarcoma
19. Phyllodes tumor
20. Immuno histochemistry and its role in diagnosis of Tumors – list four tumors.
21. Hyperbilirubinaemia
22. Flea bitten kidney
*****
Q.P. CODE: 1082

1. Enumerate the different Ulcerative Lesions of Intestine. Describe the etiopathogenesis of
Inflammatory Bowel disease. Tabulate the differences between Crohn’s disease and Ulcerative
Colitis. (3+3+4 = 10 marks)
2. A 48 years old lady presented with Bleeding per Vagina. Per Speculum examination showed an
Ulceroproliferative growth involving the external os which bleeds on touch.
a) What is the most probable diagnosis and why?
b) What is the etiopathogenesis of this condition?
c) Add a note on screening method for this condition. (2+4+4 = 10 marks)

3. Vegetations of Heart
4. Kidney lesions in Diabetic Nephropathy
6. Pathogenesis and morphology of Grave’s disease – Thyroid
7. Etiopathogenesis of Bronchial Asthma
9. Rheumatoid Arthritis
10. Basal Cell Carcinoma
11. Meningioma
12. Ewing’s Sarcoma

13. Amoebic Liver Abscess – morphology
14. Components of Fallot’s Tetrology
15. Molluscum Contagiosum
16. Causes for Subarachnoid Haemorrhage
17. Microscopic features of Schwannoma
20. Prognostic factors in Breast Carcinoma
21. Lesions associated with H. Pylori
22. Pilomatrixoma
*****
MBBS (Phase - II) Degree Examination - Dec - 2017
Q.P. CODE: 1082

1. Define and classify Cirrhosis. Describe the morphological features and complications of Alcoholic
Liver disease.
2. Classify tumours of Breast. Discuss the etiopathogenesis and pathology of Infiltrating Duct
Carcinoma.

3. Features and complications of Fallot’s Tetralogy
4. Pathogenesis and complications of Bronchiectasis
5. Morphology of Pleomorphic Adenoma
6. Role of Helicobacter Pylori in Gastric Ulcer
7. Pathogenesis and morphology of Crohn’s disease
8. Adult Polycystic Kidney disease
9. Discuss in brief etiopathogenesis of Malignant Melanoma.
10. Carcinoid syndrome
12. Pathogenesis, morphology and radiological features of Osteoclastoma

13. Morphology of Cervical Intraepithelial Neoplasia
14. Gross and microscopic features of Dysgerminoma
15. Tubercular Osteomyelitis
16. Types of Renal Calculi
17. Zollinger-Ellison syndrome
18. Role of HbA1C estimation in Diabetes
19. Cryptorchidism
20. Causes of Hydronephrosis
21. Leukoplakia of Oral Cavity
22. Importance of Reid index
*****
MBBS (Phase - II) Degree Examination - DEC-2018
Q.P. CODE: 1082

1. Define and classify Cirrhosis. Discuss the pathology and complications of Alcoholic Cirrhosis.
(4+3+3 = 10 marks)
2. A 58 years old lady presented with ill defined Hard Breast Lump which was fixed to underlying
muscle. Axillary Lymphnodes were enlarged.
a) What is your diagnosis and why?
b) What are the histological types of this Lesion?
c) Add a note on prognostic factors in this condition. (2+5+3 = 10 marks)

3. Subacute Bacterial Endocarditis
4. Types and morphology of Renal Cell Carcinoma
5. Pathogenesis of Insulin dependent Diabetes Mellitus
6. Astrocytoma
7. Teratoma – Ovary
8. Multinodular Goitre
9. Ulcerative Colitis
10. Phyllodes tumour
11. Carcinoid tumour
12. Retinoblastoma

13. Urine findings in Acute Post Streptococcal Glomerulonephritis
14. Chondroblastoma
15. Rhabdomyosarcoma
16. Small Cell Carcinoma of Lung
17. Microscopic features of Lobular Carcinoma Breast
18. Medullary Carcinoma Thyroid
19. Psammoma Bodies
20. Granulosa Cell Tumour – Ovary
21. Leukoplakia – Oral Cavity
22. Hirschsprung disease
*****
M.B.B.S. PHASE II Degree Examination – 13-Dec-2019
PATHOLOGY - PAPER – II (RS2 & RS3)

QP Code: 1082
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.

1. A 30-year-old male developed sudden onset of fever with chills. On examination, the physician
detected cardiac murmurs. His blood culture was positive for gram positive organisms. He had a
past history of pharyngitis followed by carditis when he was 5 years old.
b) What is the aetiopathogenesis of this condition?
c) Describe the morphology of the disease.
d) Enumerate the complications associated with this condition.
2. Define diabetes mellitus. Discuss the types, pathogenesis and pathology of diabetes mellitus.

3. Cirrhosis of liver.
4. Compare (in a tabular format) ulcerative colitis and Crohn’s disease
5. Malignant melanoma
6. Osteosarcoma
7. Paget’s disease of bone
8. Classification of ovarian tumors
9. Renal cell carcinoma
10. Emphysema
11. Hashimoto’s thyroiditis
12. Pathogenesis of acute pancreatitis

13. Morphology of bronchiectasis
14. Fibroadenoma
15. Precancerous lesions of esophagus
16. Types of meningioma
17. Causes of lymphadenitis.
18. Benign prostate nodular hyperplasia
19. Warthin’s tumor
20. Hydronephrosis
21. Classify Hodgkin’s lymphoma. Name the characteristic neoplastic cells seen in this condition.
22. Enumerate the risk factors of atherosclerosis.
*****
MBBS (Phase - II) Degree Examination - 25-Feb-2022
PATHOLOGY – PAPER - II (RS3)

Q.P. CODE: 1082
Draw neat, labeled diagrams wherever necessary.

1. Describe the etiopathogenesis and morphology of Carcinoma Stomach.
2. Describe the macroscopic and microscopic appearances of Myocardial infract. Briefly discuss the
laboratory diagnosis.

3. Acute pancreatitis
4. Prognostic factors of Breast carcinoma
5. Mechanism of Glomerular injury
6. Write short notes on Asbestosis.
7. Hydatidiform mole
8. Malignant melanoma
9. Pathogenesis and pathology of Hashimoto thyroiditis
10. Medulloblastoma
11. Pathogenesis of Rheumatoid arthritis
12. Classification of Germ cell tumors of testis.

13. Morphology of Fibrolamellar hepatocellular carcinoma
14. Definition and morphology of Leukoplakia.
15. Cervical carcinoma in situ
16. Berry aneurysm
17. Morphology of Giant cell tumor of bone
18. Complications of Bronchiectasis
19. Schwannoma
20. Endometriosis
21. Osteitis fibrosa cystica
22. Cryptorchidism and its complications
*****
MBBS (Phase - II) Degree Examination - 06-Feb-2023

Q.P. CODE: 1082

1. Define Cirrhosis. Classify and describe the pathology and complications of alcoholic liver cirrhosis.
2. Describe the etiopathogenesis, pathology and complications of Gastric carcinoma.

3. Pathogenesis of Atherosclerosis
4. Seminoma
5. papillary carcinoma of thyroid
6. Ulcerative colitis
7. Fibrodenoma of breast.
8. Chronic Pyelonephritis (CPN).
9. Barrett’s esophagus
10. Endometrial hyperplasia
11. Premalignant conditions of the skin
12. Classify bone tumors.

13. Name four brain tumors
14. Krukenberg tumor
15. Emphysema.
16. Causes of hydronephrosis
17. Teratoma ovary.
18. Name the pigmented lesions of the skin
19. Paraneoplastic syndromes of small cell carcinoma of the lung
20. Paget disease of breast
21. Rickets.
22. Mention types of renal stones.
*****
MBBS (Phase - II) Degree Examination - JULY-2018
Q.P. CODE: 1082

1. Classify tumours of the Ovary. Describe the morphological features of Mucinous tumours of the
Ovary.
2. Enumerate Chronic Obstructive Pulmonary diseases. Discuss the etiopathogenesis of Emphysema
and add a note on its complications.

3. Laboratory diagnosis and complications of Myocardial Infarction
4. Warthin’s tumour
5. Linitis Plastica
6. Differences between Ulcerative Colitis and Crohn’s disease
7. Pathogenesis of Type II Diabetes Mellitus
8. Nephrotic syndrome
9. Endometriosis
10. Discuss briefly about Pre-neoplastic Lesions of Skin
11. Papillary Carcinoma Thyroid
12. Seminoma

13. Define Aneurysm and mention the causes.
14. Morphological features and radiological appearance of Osteosarcoma
16. Morphology of Tuberculoid Leprosy
17. Morphology of Hepatocellular Carcinoma
18. Horseshoe Kidney
19. Morphology of Hydatidiform Mole
20. Morphology of Phyllodes tumour
21. Pituitary Adenoma
22. Multiple Endocrine Neoplasia
*****
MBBS (Phase - II) Degree Examination - 01-Aug-2022

Q.P. CODE: 1082

1. Discuss the etiology, pathology and complications of Nephrotic syndrome.
2. Describe the etiopathogenesis, morphology and complications of Infective endocarditis.

3. Peptic ulcer disease
4. Silicosis
5. Cholelithiasis
6. Benign prostastic hyperplasia
7. Morphology of Meningioma
8. Classification of ovarian tumors.
9. Paget disease of bone
10. Hepatocellular carcinoma
11. Melanoma.
12. Astrocytoma.

13. Morphological forms of Bronchiectasis
14. Morphology of cystic teratoma of ovary
15. Enumerate the conditions that cause COPD.
16. Gynecomastia
17. Liver abscess
18. Microscopic appearance of Papillary carcinoma thyroid
19. Precancerous conditions of GIT
20. Contracted kidney
21. Bowens disease
22. Name the tumors of the lung.
*****
MBBS (Phase - II) Degree Examination - 10-Jul-2023
Time: Three Hours Max. Marks: 100
PATHOLOGY – PAPER - II (RS-3)

Q.P. CODE: 1082

1. 70 year old male, complaints of loss of appetite and weight loss since 6 months. Clinical
examination revealed a mass palpable in the epigastric region. Upper GI endoscopy showed an
ulceroproliferative growth in lesser curvature of stomach
b) Describe etiopathogenesis and morphology of this condition
2. What is myocardial infarction? Discuss the etiopathogenesis with morphology. Add note on
laboratory diagnosis

3. Osteogenic sarcoma
4. Papillary carcinoma of thyroid
5. Hodgkin’s lymphoma
6. Bronchial asthma
7. Seminoma testis
8. Chronic pyelonephritis
9. Medulloblastoma
10. What is cirrhosis of liver? Describe morphology
11. Squamous cell carcinoma of skin
12. Pathogenesis of type II diabetes mellitus with late complications

13. Name three causes of massive splenomegaly
14. Morphology of chronic cholecystitis
15. Give three examples of surface epithelial tumours of ovary
16. What is nephrotic syndrome? Name the commonest cause in children
17. Microscopy of Hashimoto’s thyroiditis
18. Enumerate the stages of pneumonia
19. Microscopy of atherosclerosis
20. Fibroadenoma of breast
21. Astrocytoma
22. Gross and microscopy of hepatocellular carcinoma
*****
Q.P. CODE: 1082

1. A 10 years old boy presented with history of Sore Throat followed by Migratory Poly-arthritic and
Subcutaneous Nodules.
a) What is your probable diagnosis?
b) Discuss the etiopathogenesis.
c) Mention the morphological features in the target organ.
2. Classify Bone tumours. Discuss the pathogenesis and morphological features of Osteosarcoma.

3. Morphology of different stages of Pneumonia
4. Write a brief note on Hodgkin’s Lymphoma.
5. Etiopathogenesis of Peptic Ulcer
6. Etiopathogenesis and pathology of Alcoholic Liver disease
7. Morphology of Rodent Ulcer
8. Pheochromocytoma
9. Gross and microscopic features of Multinodular Goitre
10. Light microscopy in Minimal change disease
11. Morphology of Seminoma
12. Schirrhous Carcinoma of Breast

13. Retinoblastoma
14. Types of Emphysema
15. Microscopic features of Wilm’s tumour
16. Cholelithiasis
17. Morphology of Amoebic Liver Abscess
18. Barrett’s Oesophagus
19. Causes of Splenomegaly
20. Meckel’s Diverticulum
22. Enumerate Cystic diseases of Kidney.
*****
Q.P. CODE: 1082

1. Classify Ovarian tumours. Describe the pathology of Papillary Serous Cyst-adenocarcinoma of
Ovary. (2+8)
2. A 10 year old boy developed Migratory Arthritis of Large Joints and features of Pancarditis, after 10
days, following episode of Pharyngitis.
b) Describe the etiopathogenesis of underlying disorder. (2+8)

3. Gastric Carcinoma
4. Alcoholic Liver disease
5. Bronchial Asthma
6. Germ Cell tumours of Ovary
7. Complications of Gall Stones
8. Thyrotoxicosis
9. Intestinal Amoebiasis
10. Lung Abscess
11. Premalignant Lesions of Squamous Cell Carcinoma of Skin
12. Pyogenic Meningitis

14. Medullary Carcinoma of Thyroid
15. Kidney changes in Malignant Hypertension
16. Classification of Hodgkin’s disease
17. Causes for Splenomegaly
19. Colloid Goitre
21. Leiomyoma – Uterus
22. Scar Endometriosis
*****
MBBS (Phase - II) Degree Examination - JUNE-2019
Q.P. CODE: 1082

1. Discuss aetiopathogenesis and pathology of glomerulonephritis.
2. Define emphysema. Discuss etiopathogenesis, types and gross and microscopy of
emphysema.

3. Enumerate factors causing skin cancer. Write gross and microscopy of basal cell carcinoma.
4. Classify testicular tumors. Describe gross and microscopy of Seminoma.
5. Urolithiasis
6. Etiopathogenesis of atherosclerosis
7. Clinical manifestation of portal hypertension
8. Kidney changes in RPGN
9. Hodgkin’s lymphoma
10. Hepatocellular carcinoma – gross and microscopy
11. Alcoholic liver disease
12. Factors influencing Pneumoconiosis, add a note on silicosis

13. HPV and cancer
14. Coarctation of Aorta
15. Bowen’s disease
16. Condyloma accuminatum
17. Complications of Myocardial infarction
18. Pneumonia alba
19. Causes of splenomegaly
20. Dermoid cyst
21. Factors affecting prognosis of breast cancer
22. Complications of diabetes mellitus
*****
M.B.B.S. PHASE II Degree Examination – 20-Nov-2020
PATHOLOGY - PAPER - II (RS3)

QP Code: 1082

1. Classify ovarian neoplasms. Describe serous tumors of ovary in detail.
2. Write the diagnostic criteria for diabetes mellitus. Classify diabetes mellitus. Describe the
pathogenesis for type II DM.

3. Bronchiectasis
4. Rheumatic heart disease
5. Papillary carcinoma thyroid
6. Classification of Hodgkins lymphoma
7. Neonatal hepatitis
8. Warthins tumor
9. Phylloides tumor
10. Acute tubular necrosis
11. Osteoarthritis
12. Medulloblastoma

13. Patent ductus arteriosus
14. Consequenses and complications of myocardial infarction
15. Hyaline membrane disease
16. Morphology of iodine deficiency goiter
17. Microscopy of amoebic colitis
18. Morphology of alcoholic liver disease
19. Pyogenic meningitis
20. Pagets disease of bone – morphology
21. Microscopy of seminoma
22. Differences between nephritic and nephrotic syndrome
*****
M.B.B.S. PHASE II Degree Examination – 22-Sep-2021
PATHOLOGY - PAPER - II (RS3)

QP Code: 1082
1. Describe the pathogenesis, gross, microscopy and complications of gastric ulcer.
2. Classify ovarian tumours. Describe the gross and microscopy of mature cystic teratoma of
ovary.
3. Gross and microscopy of myocardial infarction.

4. Gall stones.
5. Causes of acute pancreatitis.
6. Chronic pyelonephritis.
7. Pathogenesis of Type I Diabetes Mellitus.
8. Coal workers pneumoconiosis.

9. Hashimoto thyroiditis.
10. Tetralogy of Fallot.

11. Emphysema.
12. Rickets.
13. Three causes of splenomegaly.
14. Three types of renal cell carcinoma.
15. Three central nervous system tumours.
16. Chocolate cyst.
17. Prognostic factors in breast cancer.
18. Tophi
19. Three precancerous lesions of skin.
20. Cryptorchidism.
21. List three gestational trophoblastic diseases.
22. Microscopy of papillary carcinoma thyroid.
*****

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QP CODE : 1027

Rajiv Gandhi University of Health Sciences, Karnataka

Time: Three Hours Max. Marks: 100 Marks

PATHOLOGY – PAPER II (RS-4)

SHORT ESSAYS 8 x 5 = 40 Marks

13. Describe the morphology of Basal cell carcinoma of skin

21 iii) Lymphoid aggregates is seen in which parotid tumour

21 iv) Anti-Gliadin antibodies are detected in

21 v) In cirrhosis of liver, collagen is laid down by

22 i) Which of the following is not a malignant tumour of germ cell origin

22 ii) Most common site for medulloblastoma is

22 iii) Histological hallmark of Paget’s disease of nipple is

22 iv) MEN IIB syndrome includes all EXCEPT

22 v) Bone tumor arising from diaphysis is

Time: Three Hours Max. Marks: 100 Marks

PATHOLOGY – PAPER II (RS-4)

SHORT ESSAYS 8 x 5 = 40 Marks

8. Lobular carcinoma Breast.

12. Microscopic picture of Malignant Melanoma.

13. Write three morphological features of urothelial carcinoma of urinary bladder

21 ii) Glomus tumor

21 iv) Anchovy Sauce type of pus seen in

21 v) Dukes staging is for

22 i) Aphthous ulcer seen in

22 ii) Ghon’s Focus seen in

22 iii) All are germ cell tumors EXCEPT

22 iv) Psammoma bodies seen in

22 v) Rodent ulcer means

Time: Three Hours Max. Marks: 100 Marks

PATHOLOGY – PAPER II (RS-4)

SHORT ESSAYS 8 x 5 = 40 Marks

SHORT ANSWERS 10 x 3 = 30 Marks

12. Malignant Nephrosclerosis.

13. Tumour markers of carcinoma breast.

21 ii) Mucin seen in

21 iii) Granulomas seen in all EXCEPT

21 v) Desmoids is most likely to arises from

22 iii) Malignancy, most commonly arising from renal pelvis is

22 iv) Osteoid seen in

22 v) Markers of Epithelial carcinoma

SHORT ESSAYS 10 x 5 = 50 Marks

SHORT ANSWERS 16 x 2 = 32 Marks

SHORT ESSAYS 10 x 5 = 50 Marks

SHORT ANSWERS 16 x 2 = 32 Marks

Time: Three Hours Max. Marks: 100 Marks

SHORT ESSAYS 10 x 5 = 50 Marks

SHORT ANSWERS 16 x 2 = 32 Marks

14. Complication of atheroma

15. Gross changes in systemic hypertensive heart disease

16. Aschoff bodies

17. Diagrammatically represent 4 forms of vegetative endocarditis

19. Graphically represent serologic markers in acute hepatitis A

20. Hydatiform mole

21. High risk HPV (Human Papilloma Virus)

22. Enlist pre-malignant lesions of skin

23. Classify ovarian sex-cord stromal tumors

24. Basal cell carcinoma

26. Endometrial hyperplasia

27. Enlist bone forming tumors