Scribd Logo
Upload

Welcome to Scribd!

  • 25 views

    Semi Solid Dosage Form

    Uploaded by

    dwivedishrishti18
    Semi-solid dosage forms are neither solid nor liquid formulations used for topical application. They contain active ingredients dispersed in a base and excipients. Advantages include local action, reduced side effects, and suitability for bitter drugs. Disadvantages include lack of accuracy, potential irritation, and bulkiness. Semi-solids are classified as externally or internally used, with examples like ointments, creams, pastes and jellies outlined.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Semi Solid Dosage Form

    Uploaded by

    dwivedishrishti18
    25 views3 pages
    Semi-solid dosage forms are neither solid nor liquid formulations used for topical application. They contain active ingredients dispersed in a base and excipients. Advantages include local action, reduced side effects, and suitability for bitter drugs. Disadvantages include lack of accuracy, potential irritation, and bulkiness. Semi-solids are classified as externally or internally used, with examples like ointments, creams, pastes and jellies outlined.

    Original Title

    SEMI SOLID DOSAGE FORM

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Semi-solid dosage forms are neither solid nor liquid formulations used for topical application. They contain active ingredients dispersed in a base and excipients. Advantages include local action, reduced side effects, and suitability for bitter drugs. Disadvantages include lack of accuracy, potential irritation, and bulkiness. Semi-solids are classified as externally or internally used, with examples like ointments, creams, pastes and jellies outlined.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    25 views3 pages

    Semi Solid Dosage Form

    Uploaded by

    dwivedishrishti18
    Semi-solid dosage forms are neither solid nor liquid formulations used for topical application. They contain active ingredients dispersed in a base and excipients. Advantages include local action, reduced side effects, and suitability for bitter drugs. Disadvantages include lack of accuracy, potential irritation, and bulkiness. Semi-solids are classified as externally or internally used, with examples like ointments, creams, pastes and jellies outlined.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    SEMI SOLID DOSAGE FORM

     Semi solid dosage form are the product having semi solid consistency. Semi
    solid are neither solid nor liquid formulation. These are the topical dosage
    form used for the protective or cosmetic function.

     They may be applied in to the skin ,mucous membranes, nasal cavity ,vagina
    or rectum. Semi solid dosage form are used in external and internal purpose.

     They contain one or more active ingredients dissolved or uniformly


    dispersed in a suitable base and any suitable excipients such as emulsifiers,
    viscosity increasing agents, anti microbial agents, antioxidants, or stabilizing
    agents etc.

    Advantage of semi-solid dosage form:


    • Probability of side effect can be reduce .
    • Local action and Site specific action of drug on affected area.
    • Convenient for unconscious patient or patient having difficulty on oral
    administration.
    • Suitable dosage form for bitter drugs.
    • More stable than liquid dosage form

    Disadvantages of semi-solid dosage form:

    • There is no dosage accuracy in this type of dosage form


    • The base which is used in the semi-solid dosage form can be easily oxidized.
    • May cause staining.
    • They are bulky to handle.
    • Application with finger may cause contamination.
    • May cause irritation or allergy to some patients.
    ▪ According to their application semi solid dosage form are classified into
    1. externally used semi solid.(ointment, cream, jellies, paste.)
    2. internally used semi solid.(suppositories, pessaries.)

    ➢ Ointment:
     They are soft, viscous semisolid preparation meant for external application
    generally skin and mucous membrane.
     They usually contains medicament which is either dissolved or suspended in
    the base.
     They have emollient and protective action on the skin to produce local or
    systemic action.
     According to application of the ointment they are classified into different
    group like antibiotic ointments, astringent ointments, antifungal ointments,
    anti inflammatory ointments etc.
     The ointment bases are classified into
    1. Oleaginous bases.
    2. Absorption bases.
    3. Emulsion bases.
    4. Water soluble bases.

    e.g; Neosporin ointment.

    ➢ Creams :
     Creams are viscous, semi solid preparation which meant for external use.
    Creams are generally softer consistency and lighter than ointment.

     Creams are two types, aqueous and oily creams. Aqueous creams are oil-in-
    water type and oily creams are water in oil type.oil in water cream is
    relatively non- greasy.

     Creams should be stored and supplied in well closed containers which


    prevent evaporation and contamination.

    e.g; Neomycin cream.


    ➢ Pastes:
    • Paste are semisolid preparation for external application.
    • Its containing a large amount 50% of finly powder solid.
    • The paste are very thick and stiff.The stiffness property of paste
    makes them useful as protective coatings.
    • When applied to the skin they adhere well, and forming a thick
    coat that protects and soothes the skin.
    e.g; Magnesium sulphate paste.
    ➢ Jellies:
    • Jellies are transparent or translucent, non greasy semi solid
    preparation used for external application to the skin.
    • They are used for medication purpose, and also lubricating
    catheters, surgical gloves and rectal thermometers.
    • The jellies are easily removed by washing.
    • Gelatin , starch, tragacanth, pectin, cellulose are used to formulate
    the jellies.
    e.g; Ephedrine sulphate jelly

    You might also like