Chromatography Standards and Solutions V1

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Chromatography Reagecon manufactures one of

the widest ranges of Physical and


Chemical Standards available on
Standards and Solutions the marketplace
2
Contents
Page

Conductivity Standards
About Reagecon 04
______________________________________________________________________________________________

Buffered Eluents and Mobile Phase 05


______________________________________________________________________________________________

Ion Chromatography Standards 06


______________________________________________________________________________________________

Dissolution Media 08
______________________________________________________________________________________________

pH Buffer Solutions 09
______________________________________________________________________________________________

Electrode Care & Maintenance 13


______________________________________________________________________________________________

Conductivity Standards 16
______________________________________________________________________________________________

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 3


About Reagecon
Reagecon, part of the Calibre Scientific Group of companies is one of the largest producers of Physical and Chemical
Standards. The company is based in an 8,000 sq. metre facility that includes a large suite of manufacturing, quality control
and research and development laboratories in Shannon, Ireland with sales offices in Shanghai and North America, Europe
and the UK through our Calibre Scientific sister companies. Reagecon employs 100 people, 50% are chemistry or science
graduates and most are involved in the development, production, testing, quality control and sales & marketing of over
10,000 product references that we currently produce. We have a very active R&D programme and develop and bring to
market many hundreds of new standards, every year.

All Reagecon manufactured products are underpinned by and demonstrate our position as a centre of excellence in the
science of Metrology. Product is manufactured, tested, and certified under the applicable ISO/IEC 17025
(A2LA Ref: 6739.03) or ISO/IEC 17034 (A2LA Ref: 6739.01) accreditation or ISO/IEC 17025 (A2LA Ref: 6739.02) for
Calibration, in one of our 20 specially equipped laboratories.

The resulting product is classified within one of 54 product families, these families are then grouped and promoted under
7 main product headings, as listed below:-

Electrochemistry Standards
Cation and Anion Standards
Pharmacopoeia Reagents and Standards
Physicochemical Standards
Total Organic and Inorganic Carbon Standards
Volumetric Solutions for Titration
Customised Standards and Reagents

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 4


Buffered Eluents

Summary of Features & Benefits

The products presented are suitable for use as Ensure consistency of products (independent,
buffering systems in either solvent or aqueous traceable, certified)
mobile phases.
Manufactured under controlled processes and batch
Significant reduction in the amount of time and certified to ensure lot-to-lot consistency and
expense required to prepare them in house - “lean reproducibility of results

labs”
Certificates of Analysis and Safety Data Sheets
available online
Frees up resources for other core activities

Produced according to USP requirements - no


deviation in materials or methodology

Reagecon’s produces a range of ready to use Buffered Eluents for Liquid Chromatography for the control of Mobile
Phase pH, when analysing ionisable compounds using HPLC and for the use of pH control when working with field
samples of non-ionisable compounds due to the presence of ionisable impurities or contaminants.

The use of Reagecon’s high quality buffer systems will minimise variations of mobile phase pH, leading to dramatically
improved selectivity, retention factor, peak shape, resolution and reproducibility. These Buffered Eluents, which are not
available from any other manufacturer, bring you multiple benefits as outlined above.

Reagecon has selected 19 most commonly recommended buffering systems from scientific literature and from the
currently published 2,400 monographs of the USP. However, there are several hundred other buffering systems
contained in the monographs and we are happy to quote for these also. The products offered are suitable for use as
buffering systems in either solvent or aqueous mobile phases.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 5


Ion Chromatography Standards

Summary of Features & Benefits

At least 18 anion and 18 cation standards available Uncertainties of measurement are calculated
according to Eurachem/CITAC guidelines and reported
Many Multi Element mixes available as expanded uncertainties at the 95% confidence level.

Manufactured to exacting specifications with an Suitable for any make or model or instrument
extended shelf life & stability
Manufactured to exacting specifications with an
This product is produced in a highly controlled extended shelf life & stability
cleanroom (ISO 7) environment, using ultra-pure
water (specially treated for the production of Ion Consistency of product - Independent, Traceable,
Chromatography Standards) and triple leached pre- Certified
cleaned bottles.
Certificates of Analysis and Safety Data Sheets
The titrimetry and spectroscopy are controlled and available online
calibrated using separate standards, so the product
comes with two layers of traceability including NIST
Standards, where available.

These standards are prepared, tested, certified and verified by following the exact same regime as already presented
for ICP-MS Standards. The raw material specifications are in most cases identical to the materials used for ICP-MS.

Additionally, the elemental cations are also analysed by ICP-MS. All results are verified on a state of the art Ion
Chromatograph, which is calibrated using high purity ISO 17034 accredited standards, similar in concentration to the
products listed below.

Controlled Environment
Reagecon’s standards are manufactured in a highly controlled clean room environment using:

High purity starting materials


Ultra-pure water, specially treated for Mass Spectroscopy Standards
High purity matrix materials
Pre-leached and pre-cleaned bottles

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 6


Options
Reagecon offers more options than almost any other manufacturer.

At least 18 anion and 18 cation standards


Many multi - element mix’s
Concentration options
Pack size options
Customised Standards

All at the highest quality and at an affordable price.

Verification of Raw Materials


All metal raw materials are assayed by titration and ICP-MS prior to manufacture. Separate CRM’s are used to control or
calibrate the titration and ICP-MS respectively. This dual process enables the assays to be cross-checked against each
other, provides two layers of traceability and quantifies the combined level of impurities in the starting material. The
product is then manufactured gravimetrically using the mass balance approach: 100% - sum of all impurities (w/w). The
assay of the final product is certified using the gravimetric result corrected for density. Prior to bottling, the finished
product is again tested and verified using an ICP-MS instrument calibrated with appropriate CRM’s and a state of the art
Ion Chromatograph.

Certification
Reagecon’s Ion Chromatography Standards are prepared gravimetrically on a weight/weight basis from the purest
available raw materials on the market. Both solute and solvent are weighed on balances calibrated by Reagecon’s
engineers using OIML traceable weights. Reagecon holds ISO/IEC 17025 accreditation for calibration of laboratory
balances. The resulting Balance Certificate of Calibration is issued in accordance with the requirements of ISO/IEC
17025.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 7


Dissolution Media

Summary of Features & Benefits

Prepared according to relevant Pharmacopoeia Ensure consistency of products (independent,


requirements without deviations on materials and traceable, certified)
methodology from Pharmacopoeia
Tested in an ISO17025 Accredited Laboratory
Manufactured with controlled processes and batch
certified to ensure lot-to-lot consistency and Full regulatory and labelling compliance
reproducibility of results. Such benefits give you
the assurance and peace of mind that in-house Major savings on storage space (concentrated
preparations cannot provide format)

Reduce preparation time, expense and free up Certificates of Analysis and Safety Data Sheets
resources for core activities available online

Ready to use Dissolution Media takes out all preparation steps, allowing you to run your dissolution test without
delay and at a reduced cost, the following graphic demonstrates the number of steps to be saved by using our ready to use
Dissolution Media
Media Preparation Weighing Mixing
• Consult relevant • Weigh ingredients • Dissolve chemicals
pharmacopoeia • Measured dangerous • Make up to Volume
• Produce BOM concentrates • Adjust to volume Ready for Testing
• Calculate quantities of • Verify Weights • Measure pH & adjust if
ingredients • Calibrate pH Meter or required
• Calibrate Balance other equipment • Mix

28-35 mins 12-36 mins 8-16 mins

Dissolution Media Concentrates take out all preparation steps up to the final mixing, simply add purified water and
mix, allowing you to run your dissolution test without delay and at a reduced cost.

Media Preparation Weighing Mixing


• Consult relevant • Weigh ingredients • Dissolve chemicals
pharmacopoeia • Measured dangerous • Mix up to Volume
• Produce BOM concentrates • Adjust to volume
Ready for Testing
• Calculate quantities of • Verify Weights • Measure pH & adjust if
ingredients • Calibrate pH Meter or required
• Calibrate Balance other equipment • Mix

28-35 mins 12-36 mins 8-16 mins

Save valuable time per batch !

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 8


pH Buffer Solutions

Summary of Features & Benefits

QUALITY PRODUCTION STABILITY


pH testing is ISO 17025 Accredited Guaranteed stability throughout entire shelf life, even
Values specified at specific temperatures e.g. after opening the bottle, eliminates the requirement
20°C/25°C to open a fresh bottle of standard every time it is used
Manufactured to exacting specifications with an LABELLING
extended shelf life & stability
Temperature dependence data is printed on the label
TRACEABILITY as are lot numbers and expiry dates for user

Electrode Care & Maintenance


Directly traceable to the IUPAC pH scale by an
unbroken chain of traceability. Reagecon achieve
this traceability through a series of comparisons,
convenience

COA & SDS


with the key reference materials being Standard Certificates of Analysis and Safety Data Sheets
Reference Materials (SRMs) manufactured by NIST available online

Extensive range of pH values


Reagecon manufactures the most comprehensive range of pH Buffer Solutions available to the marketplace, which have
been designed to suit all user requirements

Laboratory Grade Buffers, pH range 1-13


Colour Coded Buffers for Calibration pH 4, 7, 10
Professional Range (Technical, NIST/DIN & High Resolution Buffers)
Low Ionic Strength Buffers
pH Buffer Capsules

We are delighted to add several new offerings that include buffers to calibrate

Antimony Electrodes
Sterile Buffers
Colour Coded pH Buffers with a three decimal place specification.

Various packaging options are offered for ease of use e.g. Colour Coded, Twin Neck Bottles, Bag-in Box.

All are manufactured to exacting specifications with an extended shelf life and cover the pH range of pH 1.00 to pH 13.00
inclusive. All are supplied with a detailed Certificate of Analysis which outlines traceability to N.I.S.T (the N.I.S.T SRM(s) Lot
No. is stated on the certificate). Temperature dependence data is printed on the label as are lot numbers and expiry dates.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 9


Guaranteed Traceability
Reagecon’s pH buffer standards are directly traceable to the IUPAC pH scale by an unbroken chain of traceability.
Reagecon achieve this traceability through a series of comparisons, with the key reference materials being Standard
Reference Materials (SRMs) manufactured by NIST.

For proof of traceability, all of these comparisons must be made in a technically - valid manner and the accuracy of each
step must be quantified by calculating the associated Uncertainty of Measurement. Reagecon’s pH buffer standards
meet the ISO definition of traceability: “The ability to relate measurements back to a stated reference (usually an
international standard) through an unbroken chain of comparisons, each having stated uncertainties of measurement.”
Reagecon’s traceability claims are guaranteed by our accreditation to ISO/IEC 17025.

Why use traceable pH Buffers ?


Your pH measurements can only be as good as the pH buffers that you use. If your pH calibration is made using
traceable pH buffers then you have a direct link to the International pH scale for your measurements. Without this link,
you are not entitled to report your measurements in pH units so the number displayed on your pH meter is just that - a
number and is not a pH value. The common link that is achieved by traceability allows comparability of results
regardless of:

When the measurements were made


Where the measurements were made
What instrumentation was used to make the measurements

Traceable analysis is necessary for consistency and universal acceptance of your pH results - including acceptance by
regulatory bodies.

Fully Accredited
Reagecon’s pH analysis is accredited to ISO/IEC 17025 “General requirements for the competence of testing and
calibration laboratories”. Reagecon’s accreditation to ISO/IEC 17025 gives independent proof of three key areas:

Our pH analysis is technically valid and is carried out in a thoroughly controlled manner by highly - qualified
staff.
Our claims over the accuracy of our pH analysis are valid and we have properly quantified our accuracy in our
Uncertainty of Measurement calculations.
Our pH analysis is traceable to NIST SRMs. It is important to note that NIST do not police claims of traceability
to their SRMs.

Why take chances with your pH buffer supplier’s traceability? By using buffers from a manufacturer that holds ISO/IEC
17025 accreditation you have a guarantee of traceability.

Stability
Reagecon’s pH buffers have been specially formulated to ensure their stability. The packaging bottles that we use have
also been selected and tested to provide maximum stability. We have conducted stability trials on both freshly-opened
and part-full bottles of our pH buffers to validate their shelf-life - an example is given in Figure 2. This demonstrates
that Reagecon’s pH buffers will stay within their specification limits up to the stated expiry date regardless of when the
bottle was first opened (provided that the pH buffer is stored in accordance with good laboratory practice). Most of
Reagecon’s pH buffers have an expiry date of either 2 years or 3 years from the date of manufacture.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 10


This means that our pH buffers’ expiry dates are an absolute value and they have a long “Active Life”. We do not quote a
short usage period after opening the bottle and there is no need to record by hand an “Opened on date” and a “Use by
date”. With Reagecon’s pH buffers you just open the bottle and use the contents - with other manufacturers’ pH buffers
you need to record these extra dates and may need to dispose of most of the contents of the bottle at the end of its short
“Active Life”.

Figure 2: Stability Data for Reagecon pH 10.012 @ 25°C

Calibration Buffers
Reagecon pH Buffers are pre-programmed into the instruments of most major manufacturers.

Control Buffers
For increased confidence in their test measurements, analysts should regularly measure the pH of a Control Standard. If
an acceptable value is obtained from the Control Standard measurement then the analysts, can have improved confidence
that their test measurements will be correct. Reagecon’s extensive range of pH buffers means that there will be a
Reagecon pH buffer which can be used as a control buffer for all pH applications.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 11


Packaging Options
Besides regular bottles, Reagecon offer pH buffers in a wide variety
of convenient packaging options:

Twin-neck bottles. These bottles are ideal for use


with portable pH meters. Their integral calibration
chamber prevents contamination and removes the
need to carry a separate measuring container or to
decant buffers for use in the field.

Bag-in-Box containers. This packaging consists of a cardboard


box with a collapsible plastic liner. This offers a space-saving alternative to bottles and reduces the amount of
packaging waste for disposal. Every Bag-in-Box container is supplied with a tap to allow the contents to be easily
dispensed.

Capsules. The presentation of pH buffers in capsule format is an innovative concept developed by Reagecon,
and offers several advantages

RECAL Buffers. RECAL is a range of pH Buffers in a wide mouth disposable container which can be used for direct
calibration of the electrode and then discarded on completion.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 12


Electrode Care & Maintenance

Summary of Features & Benefits

COMPREHENSIVE RANGE OF PRODUCTS CERTIFICATES OF ANALYSIS & SAFETY DATA SHEETS


Reagecon offers a full suite of products to optimise Certificates of Analysis for all batches and SDS available
the life and use of electrodes. on line at anytime.

PACK SIZES UNIVERSAL USE


Most products available in a choice of pack sizes Products can be used with a wide variety of electrodes,
irrespective of brand

Electrode Care & Maintenance


according to need.

Introduction
pH is one of the most frequently and universally made measurements in science. Despite the number of people
involved in pH measurement, the practical fundamentals governing it are not widely understood. The literature
sometimes offers conflicting advice on how it is best measured and there is often uncertainty about the correct option
available to deal with individual measurement applications. What is often not fully appreciated is that the vast majority
of pH problems are related to the correct selection, care or maintenance of the electrode with particular emphasis on
the reference electrode.

This brief technical note deals specifically with the correct choice of reference Electrode Filling Solution and the
compatibility of the filling solution with the sample being measured. It is important to keep two key considerations in
mind as part of the selection process of the Electrode Filling Solution. Firstly, the issue of the compatibility between the
filling solution and the sample relates not only to direct pH measurement but also direct Ion and Redox measurement.
It is also relevant to the use of all three sensors when performing potentiometric titrations. Secondly, the direct
experience of the analyst, the operating instructions of the electrode or the detail contained within the test method
being followed, may be of most value in the selection of the correct filling solution.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 13


Correct choice of Electrode Filling Solution (Electrolyte)
A good electrolyte must fulfil a number of conditions. The equitransference of the cation/anion combination should
be as close as possible to being equimobile, have constant chloride activity, be of high electrical conductance and as

Electrode Care & Maintenance


non-chemically reactive as possible.

Concentrated or saturated Potassium Chloride (KCl) fulfils all of these conditions to a greater or lesser extent and is
the filling solution of choice in either potentiometric titrations or direct pH, redox or ion measurements where
silver/silver chloride or calomel reference electrodes are used.

However, the use of KCl in any concentration may be problematic in


the following situations:

1. The following ions can react with Cl ¯ to form insoluble


precipitates that block the diaphragm, Hg++, Cu++, Ag+, Pb++ in
such cases, a double junction electrode must be used with the
outer chamber containing either Potassium Nitrate or
Ammonium Sulphate at various concentrations. However, the
potassium may also react with anions like Perchlorate (ClO-₄) to
form Potassium Perchlorate (KClO₄ ) which is sparingly soluble.
In this situation Ammonium Sulfate can also be used as the
filling solution in the outer chamber.

2. Some electrode manufacturers recommend the use of 3M KCl


or 4M KCl saturated with Silver Chloride (AgCl) as the filling
solution of choice. In this instance silver may react with several
halides including bromides or iodides or may react with
cyanides. Most importantly, silver may also react with sulfide
which manifests itself in blackening of the diaphragm due to
blockage. There may also be ingress of the sulfide into the
electrode which will cause poisoning of the reference system,
as well as high false liquid junction potentials. In this instance,
silver free KCl can be used either as a primary electrolyte or in
the outer junction of a double junction electrode.

3. 2M Potassium Nitrate (KNO₃) + 0.001M Potassium Chloride may


be used specifically for the measurement of samples containing
silver halides or used for argentimetric titrations where silver
billet electrodes are used.

4. For pH measurement or titration in non-aqueous media or


organic solvents, Lithium Chloride in Ethanol, Methanol,
Isopropanol or Glacial Acetic Acid must be used as a filling
solution in both the inner and outer chamber.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 14


Reagecon manufacturers a complete range of Electrode Care and
Maintenance Solutions designed to help calibrate, clean, refill,
regenerate, store and extend the useful life of pH electrodes. Included in
the range are filling, storage, cleaning and regeneration solution.

Electrode Filling Solutions


A good electrolyte must fulfil a number of conditions. The
equitransference of the cation/anion combination should be as close as
possible to being equimobile, have constant chloride activity, be of high
electrical conductance and be as non-chemically reactive as possible.
Reagecon’s Electrode Filling Solutions are high quality products that fulfil
all of these criteria

Electrode Cleaning Solutions


Reagecon’s Electrode Cleaning Solutions are designed to extend the
useable life of your pH electrode and are also formulated to improve
functionality, remove materials that may effect life or functionality and
significantly improve the performance of your pH measurement system.

Electrode Storage Solution


Reagecon’s Electrode Storage Solution is a multi-faceted formulation
that maintains both the electrodes sensing and reference systems in
optimal condition, between readings or during storage. Both the sensing
membrane and the reference diaphragm should always be immersed in
this solution, rather than water, filling solution or pH buffer. Reagecon’s
Electrode Storage Solution is suitable for use with all pH electrodes
which is designed to optimise functionality, accuracy, responsiveness
and life span of a pH electrode.

Electrode Regeneration Solution


Electrodes that have not been properly stored in storage solution, or
which have been scratched, a regeneration solution could provide
further life.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 15


Conductivity Standards

Summary of Features & Benefits

COMPREHENSIVE RANGE OF PRODUCTS FULLY CHARACTERISED TEMPERATURE VALUES


Reagecon offers the widest range available on the Fully characterised temperature coefficient of variation
market of aqueous standards from 1.3 µs/cm printed on all product labels.
to 500,000 µs/cm NON-HAZARDOUS
STABILITY No shipping, storage or disposal issues
Reagecon is the ONLY producer of low level, aqueous TRACEABILITY
based, stable 1.3 µs/cm conductivity standard. All directly traceable to N.I.S.T. standard reference
ACCURACY materials. These products meet the specification
Accurate to ± 1% of target value, with the exception requirements of all the major Pharmacopoeias
of 1.30 μS/cm which has a specification of ± 0.05 COMPREHENSIVE CERTS OF ANALYSIS
µS/cm from target value Certificates of Analysis for all batches
QUALITY PRODUCTION
Standards are tested using Accredited test methods
to ISO17025

Introduction
Reagecon is the largest producer of Conductivity Standards and is credited with the invention of low level aqueous
standards. The company is still the only producer worldwide with the capability to manufacture and stabilise these
products at such low levels of conductivity. This low range of standards includes 1.3 µS ±0.05 µS/cm - the lowest
aqueous Conductivity Standard available. The following summary details the principle features and benefits of this
exciting range of products.

Extensive range of values


Reagecon offer over 45 different values of Conductivity and Total Dissolved Solids (TDS) Standards, ranging from as low
as 1.3 µS/cm to as high as 500,000 µS/cm.

Matrix Matched
The matrix of a solution is defined as “the components of the sample other than the analyte”. In all analytical
measurements, it is of utmost importance that the matrix of the standard and the sample are the same. As
conductivity measurement is, in the main, a water quality measurement, the standard used should also have an
aqueous matrix. Reagecon’s Conductivity Standards are all aqueous based, thereby eliminating any errors attributable
to matrix mismatch.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 16


Non-Hazardous
As Reagecon’s Conductivity Standards are aqueous, they are non-hazardous. They offer the following benefits over
solvent-based Conductivity Standards

Ease and cost of shipping, without the need to provide hazardous goods’ paperwork
Reduced Health & Safety requirements for storage and use
Ease and cost of disposal - solvent-based Conductivity Standards require expensive, specialised disposal to
comply with environmental regulations.

Guaranteed Stability
As a result of the extensive R&D that led to our innovative manufacturing process, Reagecon can guarantee the stability
of their complete range of Conductivity Standards over their entire shelf life. The stability offered by Reagecon’s
Conductivity Standards varies from that of their competitors in one vital area. We can guarantee that our Conductivity
Standards will remain within specification, (up to their expiry date), right through their working life, regardless of when
the bottle was first opened provided Good Laboratory Practise is adhered to. This eliminates the need to open a fresh
bottle of standard every time the product is used. (The 1.30 µS/cm Conductivity Standard is packaged in single-dose
bottles and each bottle when opened can only be used once.) The shelf life of the products from their date of
manufacture are given below.

Accuracy
All standards have a specification of ± 1%, except 1.30 µS/cm, which has a specification of 1.25 - 1.35 µS/cm. This high
level of accuracy enables the standards to be used as calibrators and/or controls in fulfilment of the most exacting
industrial statutory requirements, for example the United States Pharmacopoeia Monograph for Water for Injection.

Accreditation
Reagecon’s conductivity measurement has been covered in the scope of our accreditation to ISO 17025 “General
Requirements for the competence of Calibration and Testing Laboratories” and its predecessor, EN 45001, since 1990.
ISO/IEC 17025. Achieving accreditation involves fulfilling many highly technical criteria, including fully validating our test
methods and instrumentation systems and characterising our measurement uncertainty. Reagecon’s accreditation
proves the technical competence of our personnel, the technical validity of our test procedures and the traceability of
our measurements. Therefore, in purchasing a Conductivity Standard from us, not only do you have transparent
traceability to primary standards, but you also have confidence that our standards are of a well-defined and tightly
controlled specification.

All values are Certified & Traceable


Comprehensive Certificates of Analysis are available for all of Reagecon’s Conductivity Standards, including detailed
information on:

Product Number
Lot Number
Expiry Date
Mean specific conductance
Date of Measurement
Assay Limits
Test Method Used
Uncertainty of Measurement and Traceability Data

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 17


The complete range is traceable to primary standards from the United States National Institute for Standards and
Technology (NIST). The traceability of these standards is proven by the inclusion of conductivity testing in our ISO 17025
accreditation. It is a fundamental requirement of ISO 17025 that traceability is proven.

Characterised Temperature Coefficient of Variation


Reagecon’s standards are aqueous based and consequently have a very low temperature coefficient of variation. A
table of conductivity variation with temperature is printed on the label of each bottle. This feature provides the user
with all the information necessary to use the products across the full range of measurement temperatures encountered
for their application. Non-aqueous standards have a very high coefficient of variation which leads to measurement error
and renders the products totally unsuitable for non-temperature controlled conditions, or field work.

Unparalleled Technical Support


We have been manufacturing Conductivity Standards for over 20 years. In that time, we have built up a vast resource of
technical expertise on all aspects of conductivity measurement. The members of Reagecon’s Technical Services
Department have written a comprehensive series of papers covering all of the practical requirements for accurate
conductivity measurement. These papers are available via our website www.reagecon.com

Our Technical Services team is always on hand to answer any questions regarding the selection and use of conductivity
instruments, sensors and standards.

© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 18


© 2023, Reagecon Diagnostics Ltd | Chromatography Standards and Solutions 19
For further information or enquiries, please contact us:

Tel: +353 61 472622


Email: [email protected]
www.reagecon.com

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