BANGALORE UNIVERSITY

V& VI Semester Chemistry Syllabus

for
B.Sc. / B.Sc. Honours Program

(To be implemented from the academic year 2023-24)

DEPARTMENT OF CHEMISTRY
Bangalore University
Jnanabharathi
Bangalore-560056

AUGUST-2023
 Preamble
The Board of studies in UG Chemistry headed by Prof G Krishnamurthy,
the Chairman, Department of Studies in Chemistry, Jnanabharathi Campus, Bangalore
University had the thorough discussions on the syllabus of V and VI semester
Chemistry for BSc/ BSc Honors courses using the syllabus provided by the NEP
Chemistry syllabus drafting Committee. This syllabus has to be accepted for the
academic year 2023-24.
The Core committee consisting of the faculty members of different branches
of Chemistry namely Analytical, Physical, Inorganic and Organic Chemistry which
comprising the BOS and also additional faculty members from different UG Colleges
of Bangalore University have made effective joint brainstorming discussions and
arrived at a Syllabus in Chemistry for V and VI semesters on 28.08.2023 and
29.08.2023.
The final syllabus incorporating all the suggestions was finally approved by
the members of the Board of Studies in Chemistry (UG) on 29.08.2023. The following
Faculty Members of the Core Committee were involved in the preparation of the
Chemistry Syllabus.
Physical Chemistry Section
1. G. Krishnamurthy
2. K. Ramakrishna Reddy
3. P. Nagegowda
Inorganic and Biological Chemistry
4. Dr. Lakshmi Devi
5. Dr. Muddukrishna K R
6. M. Shubha
7. Nebula Murukesh
8. B. M. Sreenivas
9. Dr. Shalini K. S.
10. Dr. Shashikumar N. D.
Organic Chemistry Section
11. Dr. Vasudeva Reddy K
12. Dr. Sumaiya Tabassum
Sd/-
PROF. G. KRISHNAMURTHY
CHAIRMAN
BOS in Chemistry (UG)
Bangalore University
Bangalore -560056

2
 PROGRAMME STRUCTURE

Hours / Examination Pattern Max. Duration of Total

week & Min. Marks /Paper Exam (hours) Mark Credits
s/
ESE Practical paper

Se Th Pra
mes Title of the Teaching eo Prac Ma Min Ma Theor Practi The ctic
ter Paper Hours ry tical x. . IA x. Min. IA y cal ory al
V DSC-5:
Organic and
60 4 - 60 22 40 - - - 3 - 100 4 -
Physical
Chemistry -III

DSC LAB 5:
Organic and
60 - 4 - - - 25 9 25 - 3 50 - 2
Physical
Chemistry -III

DSC-6:
Inorganic and
60 4 - 60 22 40 - - - 3 - 100 4 -
Biological
Chemistry-III

DSC LAB 6
Inorganic and
60 - 4 - 3 50 - 2
Biological
Chemistry- III
VI DSC-7:
Organic and
60 4 - 60 22 40 - - - 3 - 100 4 -
Physical
Chemistry -IV
DSC LAB 7:
Organic and
60 - 4 - - - 25 9 25 - 3 50 - 2
Physical
Chemistry - IV

DSC-8:
Inorganic and
60 4 - 60 22 40 - - - 3 - 100 4 -
Biological
Chemistry- IV

DSC LAB 8:
Inorganic and
60 - 4 3 50 2
Biological
Chemistry- IV

3
4
5
 PROGRAMME OUTCOMES (POs)
By the end of the programme the students will:
PO 1. Understand the basic principles of various branches of Chemistry
PO 2. Learning all adequate theoretical concepts
PO 3. Analysing the leant concepts
PO 4. Conceptualizing the learnt concepts
PO 5. Developing the skill to apply the concepts for broader learning
PO 6. Apply the key concepts and standard methodologies to solve problems related to
Chemistry
PO 7. Apply methodologies to the solution of unfamiliar types of problems
PO 8. Demonstrate a range of practical skills to conduct and infer experiments independently
and in groups
PO 9. Exhibit skills leading to employability in Chemistry and allied industries
PO 10. Comprehend the fundamental aspects of research in Chemistry
PO 11. Possess the level of proficiency in subject required for post-graduation as well as for
pursuing research in Chemistry and related interdisciplinary subjects
PO 12. Design solutions stemming from the application of Chemistry to the local issues

6
 DISCIPLINE CORE COURSE SEMESTER – V (NEP)
DSC-5- Chemistry –V: Organic and Physical Chemistry
Contact hours- 60 Credit point-4
Workload-4 h/week Each unit: 15h
COURSE OBJECTIVES
1. Recognize and classify alcohols, thiols, and phenols based on their structural characteristics.
2. Explore the reactivity of alcohols, thiols, and phenols, including their reactions with various
reagents and under different conditions.
3. Explore the reactivity of aldehydes and ketones, including their reactions with various reagents,
such as nucleophiles and oxidizing agents.
4. Explore the reactivity of aldehydes and ketones, including their reactions with various reagents,
such as nucleophiles and oxidizing agents.
5. Learn methods for the synthesis of carboxylic acids, including laboratory techniques and
industrial processes.
6. To impart the concepts of photochemistry and study beer lamberts law and to understand the
photochemical and photophysical processes and their quantum yield expressions. And also to acquire
knowledge on nuclear reactions and radioactive decay
7. To develop expertise on the fundamental concepts of quantum mechanics and its application
in chemistry
8. To know different types of electrochemical cells, types of electrodes and electrode potential

COURSE SPECIFIC OUTCOMES (COs)

After the completion of this course, the students would be able to
1. Demonstrate a solid understanding of the properties, structures, and nomenclature of alcohols,
thiols, and phenols and to perform laboratory experiments safely and effectively, including the
synthesis and analysis of alcohols, thiols, and phenols.
2. Evaluate the suitability of different synthetic methods and reagents for specific applications
involving aldehydes and ketones and understanding the practical applications of aldehydes and
ketones & carboxylic acids in various industries, research, and daily life.
3. Explain the Lambert-Beer’s law, the laws of photochemistry, photochemical and photophysical
processes as well as to calculate the quantum yield of photochemical combinations. Also to
develop an understanding on nuclear stability, nuclear reactions, radioactive decay and
applications of nuclear and radiochemistry
4. Explains the fundamental concepts of quantum mechanics and its application in chemistry
5. Learning about the fundamental of electrochemistry and to determine the electrode potential of
a half cell, identify different types of electrodes, construct cells and demonstrate its application.

7
ORGANIC CHEMISTRY III:
UNIT-I
Alcohols,Thiols and Phenols 10h
Alcohols: Introduction and classification. Methods of preparation-(i) From carbonyl compounds-
reduction of aldehydes and ketones (by Meerwein-Pondorff- Verley reaction);(ii) from acids and esters
(by reduction with LiAlH4); (iii) From alkenes (by hydroboration oxidation with alkaline
peroxide); (iv)hydration of alkenes.
Reactions of alcohols: Acidic nature, esterification, oxidation of alcohols with KMnO4. Comparison
of the reactivity of 1°,2°and 3°alcohols- Lucas test, oxidation with K2Cr2O7.
Glycols: Preparation from alkenes using OsO4, KMnO4 and from epoxides.Oxidation of glycols by
periodic acid and lead tetraacetate with mechanism. Pinacol- pinacolone rearrangement.
Glycerol:Preparation from propene and from oils/fats. Uses. Reactions of glycerol: (i) nitration, (ii)
action of concentrated H2SO4 and (iii) oxidation by periodic acid.
Thiols: Nomenclature. Methods of formation and chemical reactions (with sodium,NaOH,metal
oxides, formation of thioesters and oxidation with mild and strong oxidizing agents). Uses of dithianes.
Introduction of umpolung character (reversal of polarity) in carbonyl compounds.
Phenols
Classification. Acidic nature - Comparison of acidic strength of phenol with alcohols and
monocarboxylic acids.Effect of electron withdrawing –NO2 group and electron donating –CH3 group
on acidity of phenols at o-, m-, p- positions. Pechmann reaction, Mechanism of Reimer-Tiemann and
Kolbe-Schmidt reactions. Industrial applications of phenols: Conversion of phenol to (i) aspirin,
(ii)methyl salicylate, (iii) salol, (iv)salicylsalicylic acid.

Aldehydes and Ketones 5h

Nomenclature. Preparation of aldehydes: (i)from acid chlorides (Rosenmund reaction), (ii)
Gattermann- Koch aldehyde synthesis. Preparation of Ketones: (i) From nitriles,from carboxylic acids
with alkyl lithium, (ii) from acid chlorides with metal alkyls.
Mechanisms of Cannizzaro reaction, Benzoin condensation, Reformatsky Reaction and Knoevenagel
condensation.General mechanism of condensation with ammonia and its derivatives
(NH2−R;R=−NH2,−OH,−NH−CO−NH2).
Reduction:Reduction by LiAlH4 and NaBH4.Mannich reaction.Mechanisms of Clemmensen and
Wolff-Kishner reductions.

UNIT -II
Carboxylic acids and their derivatives 10h
Carboxylic acids:Nomenclature,Classification-mono,di,tricarboxylic acids,hydroxy acids- lactic acid,
tartaric acid and citric acid. Mono carboxylic acids: preparation- acid hydrolysis of nitriles with
mechanism. Acidic strength- pKa values.
Effect of substituents on the strength of aliphatic and aromatic carboxylic acids. Comparison of acid
strength of formic and acetic acid, acetic acid and mono-chloro, dichloro, trichloroacetic acids, benzoic
and p-nitrobenzoic acid, p-aminobenzoic acid, explanation.

8
Reactions: Formation of esters, acid chlorides, amides and anhydrides. Hell-Volhard- Zelinsky
reaction, decarboxylation and reduction using LiAlH4.
Di and tri carboxylic acids: Action of heat on dicarboxylic acids -oxalic acid, malonic acid, succinic
acid, glutaric acid and adipic acid. Reactions of tartaric acid and citric acid- action of heat and reduction
with HI.
Acid derivatives: Acid chlorides- hydrolysis, reaction with alcohol, ammonia and lithium dialkyl
cuprates. Acid anhydrides –acetic anhydride- hydrolysis, reaction with alcohol and ammonia.
Amides-hydrolysis,reduction,Hoffmann degradation.
Esters-acid hydrolysis and alkaline hydrolysis, ammonolysis and alcoholysis.

Amines 5h
Classification. Preparation of alkyl and aryl amines- reductive amination of carbonyl compounds,
Gabriel phthalimide synthesis. Basicity of amines in aqueous solution: Inductive, resonance, steric and
solvation effects on the basicity of amines. Reaction of amines as nucleophiles– Methylation,
quaternary salts, Hofmann elimination with mechanism. Distinguishing reactions of primary,
secondary and tertiary amines.
Diazotization and synthetic applications of diazonium salts. Sandmeyer’s reaction. (Conversion to
chlorobenzene, bromo benzene and benzonitrile), hydrolysis, reduction (to phenyl hydrazine and
aniline), coupling reactions to give azo dyes (p-hydroxy azo benzene and 1- phenyl azo-2-naphthol).

PHYSICAL CHEMISTRY III:

UNIT-III
Photochemistry 6h
Characteristics of electromagnetic radiation, Lambert-Beer’s law and its limitations, physical
significance of absorption coefficients.
Laws of photochemistry. Grotthus-Draper law, Stark-Einstein law – Statements, differences between
photophysical and photochemical processes-any four differences with examples.
Comparison of photochemical and thermal reactions with an example each. Quantum yield definition,
Magnitude of Quantum yield of photochemical combination of (i) H2 and Cl2 (ii) H2 and Br2 (iii)
dissociation of HI (iv) dimerisation of anthracene: reason for low, high and medium quantum yields.
Photosensitization-definition with example, photostationary equilibrium – definition and example.
Singlet and triplet states – definitions. Fluorescence, phosphorescence, luminescence, bioluminescence
and chemical sensors definitions of all these with suitable examples.

Nuclear and Radiochemistry. 9h

Nucleus: Structure and stability, binding energy calculations. Instability of the nuclei, radioactive
decay law, half-life: numerical problems. Radioactive equilibrium, radioactive series. Artificial
radioactivity: Nuclear reactions induced by γ-radiation, α, n, p,and d particles. Nuclear fission and
fusion. Nuclear reactors, Breeder reactors, atomic energy programme in India. Isotopes- use of radio
isotopes in tracer technique, agriculture, medicine, food preservation and Carbon dating-Numerical
problems.

9
 UNIT-IV
Quantum Mechanics 8h

Concepts of Operators: Laplacian, Hamiltonian, Linear and Hermitian operators. Angular Momentum
operators and their properties. Commutation of operators. Solutions of Schrödinger wave equation for
a free particle, particle in a three-dimensional box. Quantum mechanical degeneracy, tunneling (no
derivation). Application of Schrödinger equation to harmonic oscillator, rigid rotator.

Application of Schrödinger wave equation to hydrogen atom. Schrödinger equation to hydrogen atom
in spherical polar coordinates. Separation of variables.

List of wave functions for few initial states of hydrogen like atoms. The Stern-Gerlach experiment and
the concept of electron spin, spin orbitals (elementary idea only) and Pauli’s exclusion principle.

Approximate methods: Need for approximate methods. Statement of variation theorem and application
to simple systems (particle-in-a-box, harmonic oscillator, hydrogen atom).
Electrochemistry II 7h
Galvanic cell: conventions of representing galvanic cells-reversible and irreversible cells, derivation
of Nernst equation for single electrode potential (free energy concept).
Weston-cadmium cell: Determination of Emf of a cell by compensation method. Determination of E
of Zn/Zn2+ and Cu/Cu2+electrodes.
Liquid junction potentials, elimination of liquid junction potential.
Types of electrodes: Metal and gas electrodes (chlorine), metal/metal insoluble salt electrodes, redox
electrodes. Reference electrodes-standard hydrogen electrode, calomel electrode, quinhydrone
electrode and glass electrode. Determination of pH using these electrodes. Numerical problems.
Concentration cells: (i) Emf of concentration cells (ii) determination of solubility of sparingly soluble
salts and numerical problems. Redox electrodes, Emf of redox electrodes. Potentiometric titration
involving only redox systems

DSC LAB 5: Chemistry Practical -V: Organic and Physical Chemistry Practicals
ORGANIC CHEMISTRY PRACTICALS
Preparations(onestage)
1. Cannizzaro Reaction:Benzaldehyde.
2. Fries Rearrangement:Phenylacetate.
3. Sandmeyer Reaction: 4-Chlorotoluene From 4-toluidine.
4. Pechmann Reaction:Resorcinolandethylacetoacetate.
5. Oxidation of Cyclohexanol.
6. Preparation of S-Benzylthiuronium chloride.
7. Synthesis of P-iodonitrobenzene
8. Synthesis of Phenyl-2,4-dinitroaniline.
9. Synthesis of 2,4,6-tribromoaniline.

10
PHYSICAL CHEMISTRY PRACTICALS
1. Verification of Beer's Law for Cu2+ ions
2. Verification of Beer's Law for Fe2+ ions
3. Estimation of Fe2+ ions concentration in the given solution by titration of FAS versus KMnO4
through colorimetric method.
4. Estimation of Fe2+ ions concentration using EDTA through colorimetric method.
5. Study the hydrolysis of methyl acetate in presence of two different concentrations of HCl and
report the relative strength.
6. Study the hydrolysis of methyl acetate in the presence of HCl at different temperatures and
report the energy of activation
7. Evaluation of Arrehenius parameter for the reaction between K2S2O8 versus KI (first order).

Pedagogy:
Practically learning; Assignments; Seminars/ Presentations; Viva-voce;
Quiz; ICT (online) learning.

Course Articulation Matrix:

Mapping of Course Outcomes (COs) with Program Outcomes (POs 1-12)
Course Articulation Matrix relates course outcomes of course with the corresponding
program outcomes whose attainment is attempted in this course. Mark ‘X’ in the
intersection cell if a course outcome addresses a particular program outcome.

COs \ POs 1 2 3 4 5 6 7 8 9 1 1 1
0 1 2

CO 1 3 2 3 2 1 3 1 2 2 3 1 1

CO 2 3 2 2 1 3 3 1 3 2 1

CO 2 3 2 3 1 2 1 1

CO 3 2 1 2 3 1 3 2 2 3 1

CO 3 3 1 2 3 1 3 2 1 1

Note: High = 3; Medium = 2; and Low = 1.

11
REFERENCES

1. Advanced Organic Chemistry. Arun Bahl and B.S Bahl, 22nd Edn, New Delhi, 2016.

2. Organic Chemistry, Volumes I and II, I L Finar, Longman, (1999).

3. Organic Natural products. Gurudeep and Chatwal, Vol I , 2019.

4. Chemistry of Natural products 1 & 2. OP Agarwal, 2019.

5. Organic Chemistry, R T Morrison and R N Boyd, Prence-Hall, (1998).

6. Organic reactions and their mechanisms. Kalsi. P.S, 2nd Edn, New Delhi, 2000.

7. A textbook of Organic Chemistry. OP Agarwal, 2012.

9. Spectroscopy of Organic compounds. Kalsi. P.S, 6th Edn 2004.

10. Spectrometric identification of organic compounds, R.M. Silverstien & F.X.Webster.1998.

11. Physical Chemistry, P. W. Atkins, Julio de Paula, ELBS, 7th ediBon, (2002).

12. Physical Chemistry: A Molecular Approach, McQuarie and Simon, Viva, New Delhi, (2001).

13. Physical Chemistry- P. Atkins and J. D. Paula, 9th Edn., Oxford University Press (2010).

14. Principles of Physical Chemistry, 4th Edition B. R. Puri and L. R. Sharma and M.
S.Pathania, S. L. N. Chand & Co., 1987

15. Introduction to Quantum Chemistry, A. K. Chandra, Tata McGraw Hill, (1988).

16. Quantum Chemistry, Ira. N. Levine, PrenBce Hall, New Jersey, (1991).

17. Quantum Chemistry, R. K. Prasad, New Age InternaBonal, 2nd ediBon, (2000).

18. Quantum Chemistry through problems and solutions, R. K. Prasad, New Age
InternaBonal (1997).

19. Chemical Kinetics- K. J. Laidler, McGraw Hill. Inc. New York (1988).

20. Principles of Chemical KineBcs - House J. E. Wm C Brown Publisher, Boston, (1997).

21. Kinetics and Mechanism - A. A. Frost and R. G. Pearson, John-Wiley, New York, (1961).

22. Chemical Kinetic Methods - C. Kalidas, New Age InternaBonal Publisher, New Delhi (1995)

(Practicals)

1. Findlays practical physical chemistry revised by P. B. Levi. Z, Longman's London (1966).

12
 2. Experiments in Physical Chemistry by Shoemaker and Garland, McGraw Hill InternatIonal.
(1966)
3. Advanced Practical Physical Chemistry by J. B. Yadav, Goel Publications Meerut (1988)
4. Senior Practical Physical Chemistry by B. C. Kosla, Simla Printers New Delhi (1987)
5. Experimental Physical Chemistry by Daniel et al., McGraw Hill, New York (1962).
6. Practical Physical Chemistry by A.M James and P. E. Pritchard, Longman's Group Ltd (1968)
7. Experimental Physical Chemistry by R. C. Behra and B Behra, Tata McGraw, New Delhi
(1983)
8. Physical Chemistry Laboratory Principles and Experiments by H. W. Salberg J. I. Morrow, S.
R. Cohen an Green Macmillan publishing Co.,.New York (1994).
9. Textbook of Practical Organic Chemistry- A. I. Vogel, (1996).
10. Textbook of Quantitative Organic Analysis- A. I. Vogel, (1996).

DISCIPLINE CORE COURSE SEMESTER – V (NEP)

DSC-6 Chemistry -VI: Inorganic and Biological Chemistry
Contact hours- 60 Credit point-4
Workload-4 h/week Each unit: 15h

COURSE OBJECTIVES
1. To teach students the concept of nomenclature of coordination compounds, geometries (e.g.,
octahedral, tetrahedral, square planar), and the factors that influence the geometry of
coordination complexes by taking various examples.
2. To understand how coordination chemistry interfaces with other branches of chemistry and
related fields, such as bioinorganic chemistry and organometallic chemistry.
3. To develop a solid understanding of the different materials used in industry, including their
properties, applications, and manufacturing processes.
4. The requisite background knowledge in the field of Biochemistry.
5. A thorough knowledge about the structure, chemistry and functions of biomolecules like
carbohydrates, lipids and proteins.
6. A knowledge about the salient features of nucleic acids.
7. The principle and the applications of Blotting and Electrophoretic techniques.
8. The basic characteristics of enzyme and its classification, mechanism enzyme action, enzyme
kinetics, enzyme inhibition and co-enzymes.

13
COURSE SPECIFIC OUTCOMES
After the completion of this course, the students would be able to
1. Define and explain what coordination compounds are, including their structure, bonding, and
properties.
2. Understand the practical applications of coordination compounds in various fields, such as
catalysis, medicinal chemistry, and materials science.
3. Gain knowledge of the manufacturing and processing methods for various industrial
materials, including the techniques used to shape, heat treat, and finish them.
4. Exposed to a strong theoretical and practical background in fundamental concepts. Also to
get insights of multiple important technical areas of Biochemistry.
5. Able to correlate structure and function of biomolecules like carbohydrates, lipids and
proteins.

INORGANIC CHEMISTRY III:

UNIT-I
Coordination and Organometallic compounds 15h
Coordination compounds, ligands and their classification (mono, bi, tri, tetra, penta and hexa dentate
ligands) and ambidentate ligands, coordination number, nomenclature of coordination compounds in
detail. Theories of structure and bonding (Explanation for the formation of complexes by Werner’s
Theory in detail and its limitations). EAN rule, Valence bond theory- postulates, low spin and high
spin complexes with examples, limitations of VBT. Crystal field theory (octahedral, tetrahedral and
square planar complexes). Crystal field splitting and crystal field stabilization energies, limitations of
CFT. Magnetic properties of [CoF6]3−, [Co(NH3)6]3+, [Fe(CN)6]4−, [Fe(CN)6]3−. Spectral properties
of [Ti(H2O)6]3+, [Co(H2O)6]3+,
[CoCl4]2−. Isomerism-Structural: ionization, linkage, hydrate and coordination isomerism with
examples. Stereoisomerism-geometrical and optical isomerism with examples. Organometallic
compounds – ligands, classification (hapticity). Synthesis and structure of K[PtCl3(η2-C2H4)] and
[Fe(η5 - C5H5)2].
Metal carbonyls – Cr(CO)6, Co2(CO)8, Mn2(CO)10; eighteen electron rule and its deviations with
examples.
Applications of coordination/organometallic compounds:cis-platin in cancer therapy, Na2Ca EDTA in
the treatment of heavy metals (Pb, Hg) poisoning, Wilkinson’s Catalyst in alkene hydrogenation,
Monsanto acetic acid process.

UNIT-II
Industrial Materials 15h
Refractories: Properties, classification, determination of PCE values.
Abrasives – definition and classification with examples, applications, hardness, manufacture and
importance of carborundum and tungsten carbide.
14
Glass: Properties, types, manufacture of soda glass. Composition and applications of borosilicate,
metallic glass, optical glasses and polycarbonate glasses, safety glass, fire and bullet proof glasses.
Ceramics: Raw materials and their roles, varieties of clay, production of ceramic ware, glazing,
ceramic insulators.
Cement: Raw materials grades, manufacture of Portland cement (by wet process), setting of cement.
Paints and Varnishes: Constituents of oil and emulsion paints and their role, constituents of varnishes.
Fuels: Characteristics, Calorific value and its determination using bomb calorimeter, Coal- Varieties,
Gaseous fuels-advantages, constituents and their significance, production of Coal gas and composition
of LPG. Octane number.
Explosives: Classification, preparation of dynamite and TNT.
Propellants: Characteristics, classification, and their applications.

BIOLOGICAL CHEMISTRY I:
UNIT-III
Essential biological concepts 4h
Contributions of Lavosier, Wohler, Emil Fischer, Louis Pasteur, Embden, Meyerhof, Parnas. Hans
Kreb, Michaelis and Menton, Watson and Crick, Chargaff, H.G. Khorana, Knoop, Pauling, Hopkins
and Miescher. Elemental and biochemical composition of living organisms. Role of water in
biochemical systems (mention the properties of water which makes water a solvent of life). Importance
of water in biological system with special reference to the maintenance of the native structure of
biological molecules. Types of bonding in biological molecules.Biological relevance of pH and pKa
of functional groups in biopolymers, proteins and nucleic acids. Buffers, pH value of various bio-
entities, buffer action, buffer capacity and their importance in biological systems.
Carbohydrates 4h
Structure and biological importance of derivatives of monosaccharides. Amino sugars: β-D-
glucosamine, galactosamine and their N-acetylated forms: Nacetylmuramic acid (NAMA); N-
acetylneuraminic acid (NANA) Sugar acids–structure and biological importance of D- gluconic acid,
D-glucuronic acid and D-glucaric acid. Sugar phosphates–structure and biological importance of
Glucose-6-P, Fructose-6-P, Fructose1, 6-di-P, β-D-ribose-5-P and β- D-deoxyribose-5-P. Structure
and biological importance of oligosaccharides – isomaltose, cellobiose, trehalose. Polysaccharides -
source, comparative account of partial structure and biological function of starch, glycogen, cellulose,
chitin and insulin.
Lipids 4h
Introduction, Classification. Fatty acids–definition, classification as saturated and unsaturated with
examples and structure (lauric, myristic, palmitic, stearic, oleic, linoleic, linolenic and arachidonic
acids). Triglycerides–Structure of simple and mixed glycerides, properties of triglycerides- acid and
alkali hydrolysis, saponification number and its significance, iodine number andits significance.I odine
number of different oilsrancidity (oxidative and hydrolytic).
Nucleic acids 3h
Types–Components of nucleic acids, bases, nucleosides and nucleotides with structures. Partial

15
structure of polynucleotide. Structure of DNA (Watson - Crick Model) and RNA. Biological roles of
DNA and RNAs. Protein-nucleic acid interaction- chromatin and viral nuclear capsid

UNIT-IV
Proteins 5h
α-amino acids: Introduction, structure, classification on the basis of polarity of R-groups, essential and
non-essential amino acids, ionic properties and reactions of amino acids with alcohol, nitrous acid and
Ninhydrin. Peptide bond, nomenclature and classification of peptides, Levels of organizations of
Protein: Primary structure, Secondary structure (α-helix, triple helix eg., Collagen and β-pleated sheet)
forces stabilizing secondary structure, tertiary structure and forces stabilizing it, quaternary structure.
Importance of primary structure by taking sickle cell anaemia as example.
Hormones 2h
Definition. Classification - a) amino acid derivatives (epinephrine and thyroxine); b) peptide (oxytocin
and vasopressin) and polypeptide hormones (insulin and glucagon); c) Steroid hormones
(progesterone, testosterone) with functions. Role of insulin and glucagon in glucose homeostasis.
Mediators of hormone action – Ca2+, cyclic AMP.

Enzymes 6h
Introduction, Holo enzyme (apo enzyme and coenzyme). Active site, specificity. Classification of
enzymes (EC code number not required). Enzyme substrate interaction- Fischer and Koshland models.
Enzyme kinetics–factors affecting rate of enzymatic reactions – enzyme concentration, substrate
concentration, pH and temperature (mention M. M. equation). Allosteric enzymes–definition and
example Enzyme Inhibitions- Competitive, non-competitive and uncompetitive inhibition with one
example for each. Co- enzymes and cofactors and their role in biological reactions.
Biochemical techniques 2h
Principle and applications Electrophoresis–cellulose acetate membrane electrophoresis and PAGE.
Blotting techniques- Basic principle, types and application.

DSC LAB 6 ; Chemistry Practicals -VI:

Inorganic and Biological Chemistry Practicals

INORGANIC CHEMISTRY PRACTICALS

VOLUMETRIC ANALYSIS
1. Estimation of Zinc using EDTA.
2. Estimation of Nickel using EDTA and standard zinc sulphate.
3. Determination of Total Hardness of Water using EDTA
4. Estimation of Copper in Brass.
5. Estimation of Percentage of Iron in Haematite ore using barium diphenylamine sulphonate as
an internal indicator.

16
BIOLOGICAL CHEMISTRY PRACTICALS
1. Preparation of buffers and determination of their pH values using pH meter.
2. Estimation of reducing sugars by Hegdorn-Jensen method.
3. Estimation of lactose in milk by Nelson-Somogi’s method.
4. Estimation of creatinine by Jaffe’s method.
5. Estimation of inorganic phosphate by Fiske-Subbarow method.
6. Estimation of total reducing sugars by DNS (dinitrosalicylic acid) method.
7. Isolation of lactose and casein from milk and estimation of lactose by colorimetric method.

Pedagogy:
Practically learning; Assignments; Seminars/ Presentations; Viva-voce;
Quiz; ICT (online) learning.
Course Articulation Matrix:
Mapping of Course Outcomes (COs) with Program Outcomes (POs 1-12)
Course Articulation Matrix relates course outcomes of course with the corresponding
program outcomes whose attainment is attempted in this course. Mark ‘X’ in the
intersection cell if a course outcome addresses a particular program outcome.

COs \ POs 1 2 3 4 5 6 7 8 9 1 1 1
0 1 2

CO 1 3 2 3 2 1 3 2 2 1 1

CO 2 3 2 2 2 3 1 3 2 1

CO 2 3 2 3 1 2 1 1

CO 3 2 3 2 3 1 3 2 2 3 1

CO 3 3 2 3 2 1 3 2 1 1

Note: H = 3 ; M = 2; and L = 1.

REFERENCES :
1. Advanced Inorganic Chemistry, 6th Edition F. A. Cotton, G. Wilkinson, C. A. Murillo and
M. Bochmann-John Wiley & Sons, 1999.
2. Concise Inorganic Chemistry, 5th Edition J. D. Lee, Blackwell Science, 2001.
17
 3. Inorganic Chemistry, 4th Edition J. E. Huhee, E. A. Keiter and R. I. Keiter, Pearson
Education Asia, 2000
4. Inorganic Chemistry, ELBS 2nd Edition D. F. Shriver, P. W. Atkins and C. H. Langford,
Oxford Univ. Press 2002.
5. Principles of Inorganic Chemistry B. R. Puri and L. R. Sharma, Jauhar S. P-S. N. Chand &
Co., 1998
6. Inorganic Chemistry, 3rd Edition (ISE) A G Sharpe, Addison Wesley, 1989.
7. Basic Inorganic Chemistry, 3rd Edition F. A. Cotton, G. Wilkinson, P. L. Gaus-John Wiley &
Sons, 1995.
8. Essential Chemistry, International Edition R. Chang, McGraw Hill Co, 1996.
9. University Chemistry, 4th Edition (ISE) B. H. Mahan & R. J. Myers, Addison Wesley, 1989.
10. Essential Trends in Inorganic Chemistry C. M. P. Mingos, Oxford Univ Press, 1998.
11. Chemistry, 3rd Edition P. Atkins & L.Jones, W. H. Freeman & Company, 1997.
12. Modern Chemistry, 4th Edition D. W. Oxicby, H. P. Gills & N. H. Nachtrieb, Saunders
College Publishing, 1998.
13. Concise TextBook of Biochemistry T. N. Pattabhiraman, All India Publishers, 2000.
14. Biochemistry A. L. Lehninger et. al., CBS, 2000.
15. A TextBook of Biochemistry A. V. S. S. Rama Rao, UBSPD, 1998.
16. Biochemistry P. C. Champe and R. A. Harvey, J. B. Lippincott & Co, 1982.
17. Fundamentals of Biochemistry J. L. Jain, S. Chand & Co., 1983.
18. Biochemistry COSIP -ULP, Bangalore University, 1981.
(Practicals)
1. Vogel's Textbook of Qualitative Chemical Analysis, J. Bassett, G. H. Jeffery and J.
Mendham, ELBS (1986).
2. Vogel's textbook of Quantitative Chemical Analysis, 5th Edition, J. Bassett, G. H. Jeffery and
J. Mendham, and R. C. Denny, Longman Scientific and Technical (1999).
3. Inorganic Semimicro Qualitative Analysis, V. V. Ramanujam; The National Pub. Co. (1974).
4. Practical Inorganic Chemistry, G. Marr and B. W. Rockett, Von Nostrand Reinhold Co.,
London (1972).

DISCIPLINE CORE COURSE SEMESTER – VI (NEP)

DSC-7; Chemistry - VII: Organic and Physical Chemistry
Contact hours- 60 Credit point-4
Workload-4 h/week Each unit: 15h

COURSE OBJECTIVES
1. Recognize and classify heterocyclic compounds based on their ring structures and
heteroatoms.
2. Understand the principles and strategies involved in the total synthesis of complex natural
products.
3. To keep students informed about current market trends, emerging technologies, and the role
of innovation in the organic chemical industry.
4. To introduce students to various spectroscopic techniques, including UV-Vis, IR, NMR, and
their applications in organic compound analysis.

18
 5. To acquire and consolidate the fundamental concepts of chemical dynamics
6. To learn the basics of Voltammetry as an electroanalytical technique
7. To develop a good understanding of the electromagnetic spectrum and describe the principles
of Vibrational, Raman, Electronic and Electronic spectroscopy
8. Introduce the NMR and ESR spectroscopy and discuss the applications of spectroscopy

COURSE SPECIFIC OUTCOMES

After the completion of this course, the students would be able to
1. Apply knowledge to solve problems related to the synthesis and reactions of heterocyclic
compounds and to recognize the importance of natural products in drug discovery,
agriculture, and other applied fields.
2. Demonstrate a strong awareness of chemical safety protocols and hazard mitigation in
industrial settings and to use spectroscopic data to deduce the structure and connectivity of
organic compounds.
3. Explain the theories of chemical kinetics, thermodynamical formulation of reaction rates and
conceptualize steady state kinetics, kinetics of Chain reactions, homogeneous, enzyme
catalysis.
4. Gain expertise to explain the different methods to study the of kinetics of fast reactions. Also
to demonstrate skills to explain the principles of DME and experimental set up for cyclic
voltammetry.
5. Predict the spectroscopic technique and understand its role in the structure elucidation based
on its interaction with electromagnetic radiation.

ORGANIC CHEMISTRY IV:

UNIT: I
Heterocyclic Compounds 5h
Introduction, classification, structures, resonance and aromatic character of furan, pyrrole, thiophene
and pyridine. Methods of preparation and reactions of pyrrole, furan, thiophene, pyridine.
Mechanism of electrophilic substitution reactions. Comparison of basicity of pyrrole, pyridine and
piperidine. Preparation and reactions of indole, quinoline and isoquinoline.

Chemistry of Natural Products 10h

Carbohydrates: Introduction and classification.
Mono saccharides: Aldoses, structures of all the D-aldohexoses. Elucidation of open chain structure
of D-glucose. Mechanism of mutarotation and anomeric effect. Elucidation of ring structure of D-
glucose in detail. Ketoses:Fructose,inter-conversion of glucose and fructose.
Disaccharides: Glycosidic bond. Structures of maltose, lactose and sucrose- Haworth and
conformational structures.
Terpenes and terpenoids: Occurrence,classification and isoprene rule. Elucidation of structure and
synthesis of citral and zingiberene. Structures of limonene, menthol, α- terpineol, camphor, β-carotene,
Vitamins-A and their uses.

19
Alkaloids: Introduction, classification and general characteristics. Structural elucidation and synthesis
of nicotine. Structures and uses of ephedrine, caffeine, cocaine, atropine, quinine and morphine.

UNIT-II
Industrial Organic Chemistry 5h
Synthetic dyes: Introduction and classification. Colour and constitution. Synthesis of Congo red,
malachite green, alizarin and indigo.
Drugs: Chemotherapy, classification of drugs. Synthesis and uses of paracetamol, diclofenac,
ranitidine, sulphanilamide and chloramphenicol.
Introduction to Green Chemistry: Principles of Green chemistry and its application to the synthesis of
paracetamol.
Spectroscopy of Organic compounds 10h
UV-Visible spectroscopy: Introduction. Chromophores and auxochromes; blue shift and red shift.
Graphical representation of spectra of 1,3-butadiene, benzene and lycopene. Influence of conjugation
on UVabsorption- Comparison of UV spectra of acetone and methyl vinyl ketone. IR spectroscopy:
Introduction. Stretching frequencies of−OH (free and H-bonded), alkyl −C−H, C -C, C=C, C−C, C=O
and C−O groups (by taking suitable examples). Graphical representation of IR spectra of benzoic acid
and methyl benzoate.
NMR spectroscopy: Basic principles of proton magnetic resonance: Nuclear magnetic spin
quantum number I, influence of the magnetic field on the spin of nuclei, spin population, saturation
using radio frequency. Nuclear magnetic resonance. Chemical shift (δvalues), uses of TMS as
reference. Nuclear shielding and deshielding effects. Equivalent and non-equivalent protons. Effect of
electronegativity of adjacent atoms on chemical shift values. Spin-spin splitting and spin-spin coupling
(qualitative treatment only).
Applications of NMR spectroscopy including identification of simple organic molecules. Examples:
Shielding and deshielding effects for (i) methane (ii) CH3−Cl (iii) CH2Cl2(iv) CHCl3. Spin-spin
coupling in (i)Cl2CHCHO (ii)1,1,2- trichloroethane (iii) CH3CH2Cl.

PHYSICAL CHEMISTRY IV:

UNIT-III
Chemical Dynamics 11h
Macroscopic and Microscopic kinetics, Review of theories of reaction rate- Collision theory and
Transition State theory. Comparison of transition state theory with collision theory. Arrhenious
equation- characteristics, Significance of energy of activation, Temperature coefficient and its
evaluation, Thermodynamical formulation of reaction rates (Wyne-jones and Eyring treatment),
Reaction between ions in solutions - Influence of ionic strength on reaction rates (primary and
secondary salt effects).
Concept of Steady state kinetics, Chain reactions - chain length and chain inhibition, comparison of
photochemical and thermal reactions, Mechanisms of thermal and photochemical reactions between
hydrogen-bromine and hydrogen-chlorine. Comparative study of thermal and photochemical
hydrogen-halogen reactions. Pyrolysis of acetaldehyde, Decomposition of ethane.

20
Kinetics of fast reactions- Introduction, Study of reactions by relaxation method (Temperature and
pressure jump), flow method (Plug flow method and Stopped flow method), Flash photolysis and
Shock tube method.
Kinetics of homogeneous catalysis-kinetics of auto catalytic reactions, Comparison of enzyme
catalysed and chemical catalysed reactions, Mechanism (Lock and Key theory), Kinetics of enzyme
catalysed reactions - Henri-Michaelis- Menten mechanism, Significance of Michaelis-Menten
constant, Lineweaver-Burk plot. Effects of enzyme concentration, pH, Temperature, Activators and
Inhibitors on enzyme activity.
Electroanalytical Methods 4h
Voltammetry at a dropping mercury electrodes (DME)-Types of current obtained at DME. Ilkovic
equation and its applications. Current –potential relation for a cathodic process – half wave potential.
Cyclic Voltammetry-Principles-Experimental set up-Quantitative analysis, determination of diffusion
coefficients.

UNIT-IV
Spectroscopy 15h
Polarisation and orientation of dipoles in an electric field. Dipole moment. Induced dipole moment
(experimental determination of dipole moment not included). Clausius-Mossotti equation (only
statement). Dipole moment and structure of molecules (planar and non-planar).
The interaction of radiation with matter. Regions of electromagnetic spectrum and associated
spectroscopic techniques. Origin of molecular spectra: Born-Oppenheimer approximation. Rotational
spectra of diatomic molecules: Relationship between internuclear distance and moment of inertia.
Expression for rotational energy. Numerical problems. Criterion for absorption of radiation-selection
rule.
Vibrational spectroscopy: Hooke’s law- Expression for the frequency of SHO-force constant and its
significance. Expression for vibrational energy levels of SHO. Zero-point energy., numerical
problems. Degree of freedom of polyatomic molecules– modes of vibration for CO2 and H2O
molecules.
Raman spectroscopy: Concept of polarizability. Pure rotation, vibration, qualitative study. Stokes and
anti-Stoke’s lines-selection rules. Advantages of Raman spectroscopy over IR spectroscopy.
Electronic spectroscopy: Potential energy curves for bonding and antibonding molecular orbitals.
Electronic transitions –qualitative description of non-bonding orbitals and transitions between them.
Selection rules and Franck-Condon principle.
Electron Spin Resonance (ESR) Spectroscopy: Introduction, principle, criteria for the molecules to be
ESR active and applications.

DSC LAB 7; Chemistry Practicals-VII:

Organic and Physical Chemistry Practicals

ORGANIC CHEMISTRY PRACTICALS

Qualitative analysis: Systematic analysis and identification of organic compounds.

21
PHYSICAL CHEMISTRY PRACTICALS
1. Conductometric titration of weak acid versus weak base.
2. Determination of Critical Micellar Concentration (CMC) by conductivity method
3. Potentiometric titration of potassium dichromate with ferrous ammonium sulphate.
4. Determination of single electrode potential of Cu2+/Cu and estimate the given unknown
concentration using potentiometric titration.
5. Determination of single electrode potential of Zn2+/Zn and estimate the given unknown
concentration using potentiometric titration.
6. Titration of weak acid against a strong base using quinhydrone electrode and calculation of
pKa and Ka of the weak acid.
7. Determination of Oxidation and Reduction potential of K4Fe(CN)6/K3Fe(CN)6 system by
cyclic voltammeter

Pedagogy:
Practically learning; Assignments; Seminars/ Presentations; Viva-voce;
Quiz; ICT (online) learning.

Course Articulation Matrix:

Mapping of Course Outcomes (COs) with Program Outcomes (POs 1-12)
Course Articulation Matrix relates course outcomes of course with the corresponding
program outcomes whose attainment is attempted in this course. Mark ‘X’ in the
intersection cell if a course outcome addresses a particular program outcome.

COs \ POs 1 2 3 4 5 6 7 8 9 1 1 1
0 1 2

CO 1 3 3 2 2 3 2 3 2 3 1 2

CO 2 3 2 3 2 1 3 2 3 1 3 2 2

CO 2 3 3 2 3 1 2 1 1

CO 3 2 1 2 3 1 2 3 2 3 2 3 3

CO 3 3 1 2 3 3 1 2 3 1 2 1 2

Note: H = 3 ; M = 2; and L = 1.

22
REFERENCES
1. Advanced Organic Chemistry. Arun Bahl and B.S Bahl, 22nd Edn, New Delhi, 2016.
2. Organic Chemistry, Volumes I and II, I L Finar, Longman, (1999).
3. Organic Natural products. Gurudeep and Chatwal, Vol I , 2019.
4. Chemistry of Natural products 1 & 2. OP Agarwal, 2019.
5. Organic Chemistry, R T Morrison and R N Boyd, Prence-Hall, (1998).
6. Organic reactions and their mechanisms. Kalsi. P.S, 2nd Edn, New Delhi, 2000.
7. A textbook of Organic Chemistry. OP Agarwal, 2012.
8. Spectroscopy of Organic compounds. Kalsi. P.S, 6th Edn 2004.
9. Spectrometric identification of organic compounds, R.M. Silverstien &
F.X.Webster.1998.Physical Chemistry, P. W. Atkins, Julio de Paula, ELBS, 7th ediBon,
(2002).
10. Physical Chemistry: A Molecular Approach, McQuarie and Simon, Viva, New Delhi, (2001).
11. Physical Chemistry- P. Atkins and J. D. Paula, 9th Edn., Oxford University Press (2010).
12. Principles of Physical Chemistry, 4th Edition B. R. Puri and L. R. Sharma and M. S.
Pathania, S. L. N. Chand & Co., 1987
13. Introduction to Quantum Chemistry, A. K. Chandra, Tata McGraw Hill, (1988).
14. Quantum Chemistry, Ira. N. Levine, Prentice Hall, New Jersey, (1991).
15. Quantum Chemistry, R. K. Prasad, New Age International, 2nd edition, (2000).
16. Quantum Chemistry through problems and solutions, R. K. Prasad, New Age International
(1997).
17. Chemical Kinetics- K. J. Laidler, McGraw Hill. Inc. New York (1988).
18. Principles of Chemical Kinetics - House J. E. Wm C Brown Publisher, Boston, (1997).
19. Kinetics and Mechanism - A. A. Frost and R. G. Pearson, John-Wiley, New York, (1961).
20. Chemical Kinetic Methods - C. Kalidas, New Age International Publisher, New Delhi (1995)
(Practicals)
1. Findlays practical physical chemistry revised by P. B. Levi. Z, Longman's London (1966).
2. Experiments in Physical Chemistry by Shoemaker and Garland, McGraw Hill
InternationalEdn. (1966)
3. Advanced Practical Physical Chemistry by J. B. Yadav, Goel Publications Meerut (1988)
4. Senior Practical Physical Chemistry by B. C. Kosla, Simla Printers New Delhi (1987)
5. Experimental Physical Chemistry by Daniel et al., McGraw Hill, New York (1962).
6. Practical Physical Chemistry by A.M James and P. E. Pritchard, Longman's Group Ltd (1968)
7. Experimental Physical Chemistry by R. C. Behra and B Behra, Tata McGraw, New Delhi
(1983)
8. Physical Chemistry Laboratory Principles and Experiments by H. W. Salberg J. I. Morrow, S.
R. Cohen Green Macmillan publishing Co.,.New York (1998 ).
9. Textbook of Practical Organic Chemistry- A. I. Vogel, (1996).
10. Textbook of Quantitative Organic Analysis- A. I. Vogel, (1996).

23
 DISCIPLINE CORE COURSE SEMESTER – VI (NEP)
DSC-8; Chemistry-VIII: Inorganic and Biological Chemistry
Contact hours- 60 Credit point-4
Workload-4 h/week Each unit: 15h

COURSE OBJECTIVES
1. To encourage research and innovation in materials science, exploring new materials,
applications, and sustainable practices.
2. To develop the ability to select appropriate materials for specific engineering applications
based on their properties, performance requirements, and cost considerations.
3. To understand the principles of heat treatment, including annealing, quenching, and tempering,
and their effects on the structure and mechanical properties of metals.
4. To understand the role of transition metals as catalysts in various chemical reactions.
5. To identify practical applications of conducting polymers in electronics, sensors, and energy
storage devices.
6. The Concepts of thermodynamics and the mechanism of energy transfer in ETC
7. The knowledge of mechanism of DNA Replication, Transcription, Genetic code and
Translation Process
8. Greater ideas about Vitamins and the knowledge in the quantitative and qualitative estimation
of biomolecules
COURSE SPECIFIC OUTCOMES
After the completion of this course, the students would be able to
1. Grasp the role of fuels in energy production, such as in power generation and transportation,
and the importance of energy efficiency and renewable energy sources.
2. Apply metallurgical principles to the production, processing, and selection of materials in
various industries.
3. Understand the fundamentals of powder metallurgy and its advantages in producing complex-
shaped parts with controlled properties. Also to recognize the importance of transition metals
in various chemical processes and industries.
4. Apply knowledge of doping and processing to tailor the performance of conducting polymers.
5. To make them able to express ideas persuasively in written and oral form to develop their
leadership qualities. Also to demonstrate professional and ethical attitude with enormous
responsibility to serve the society.

INORGANIC CHEMISTRY IV:

UNIT-I
Bioinorganic Chemistry 2h
+ + 2+ 2+
Essential and trace elements in biological systems with reference to Na , K , Ca , Fe , P, Cu, V and
Ni. Metallo-porphyrins with special reference to haemoglobin, myoglobin and chlorophyll. Role of
cobalamin (vitamin-B12 coenzyme) in living systems.
Metallurgy 5h
Ellingham’s diagrams: Salient features. Selection of reducing agents using Ellingham’s diagrams.
24
Extraction of the following metals.
i) Nickel from sulphide ore
ii) Thorium from Monazite sand
iii) Uranium from Pitch blende
iv) Plutonium from Nuclear waste
Powder metallurgy 2h
Advantages of powder metallurgy and its applications. Methods of production of metal powders.
production of Tungsten powder from Wulframite.
Steel and Alloys 6h
Steel: Iron-Carbon Phase diagram, Austenite, Ferrite, Cementite and Pearlite phases.
Alloy steels: Influence of Si, Mn, Cr, Ni, Ti and W on the properties of Steel.
Ferro alloys: Production of ferro chrome, ferro manganese, and ferro silicon and their applications.
Carbon steel: classification. Heat treatment: hardening, case hardening, carbiding, nitriding, tempering
and annealing.

UNIT-II
General study of d and f block elements 6h
Transition elements: electronic configuration, atomic and ionic radii, ionization energy, oxidation
states, redox potentials, spectral and magnetic properties, catalytic activity, interstitial compound
formation.
Lanthanides and Actinides: Electronic configuration, atomic and ionic sizes, lanthanide contraction
and its consequences. Oxidation states, spectral and magnetic properties, comparison of oxidation
states, complex formation and magnetic properties of d and f block elements. Ion exchange method
for separation of Lanthanides.
Chemistry of Newer materials 5h
Conducting polymers: Introduction, definition, and examples-polyaniline, polyacetylene. Mechanism
of conduction. Qualitative treatment of doping, Properties: elasticity with high electrical
conductivities, Engineering, and biological applications.
Nanomaterials: Introduction, definition, and electronic structure. Different methods of production: Sol
gel synthesis, inert gas condensation, mechanical alloying (ball milling), plasma synthesis,
electrodeposition, and general applications.

Water Technology 4h
Types of impurities present in water. Causes for the hardness of water. Permissible levels of ions
present in water. Treatment of water for domestic and Industrial purposes by the following methods.
i) Demineralization of water by Ion exchange method.
ii) By reverse Osmosis method.

25
BIOLOGICAL CHEMISTRY II
UNIT III
Biological oxidation 7h
Bioenergetics- Introduction-stages of energy transformation. Exergonic and endergonic reactions.
Relationship between G and Keq. High energy phosphates–definition, examples, structural features of
ATP that makes ATP a high energy phosphate (electro static repulsion, opposing resonance, solvation
of ATP). Examples of high energy phosphates other than ATP. Energy coupling in biological reactions
(explain the concept with suitable examples). Biological oxidation – comparison of oxidation with
combustion using glucose as an example. Redox potentials of some biological important half reactions.
Calculation of energy yield from biological redox reaction (oxidation of NADH by oxygen, reduction
of acetaldehyde by NADH). Mitochondrial electron transport chain, oxidative phosphorylation.
Substrate level phosphorylation.
Metabolism 8h
Catabolism and anabolism (explanation with an example) – Carbohydrate metabolism, glycolysis, fate
of pyruvate. TCA cycle, energetic. Gluconeogenesis–definition, synthesis of glucose from lactate.
Fatty acid metabolism–activation of fatty acids, role of carnitine, β- oxidation pathway, energetics.
Protein metabolism–general aspects of amino acid degradation– transamination, deamination and
decarboxylation. Urea cycle.
UNIT IV
Molecular biology 7h
Central dogma of molecular biology–semi conservative replication and mechanism of DNA
replication, transcription, translation. DNA finger printing – Definition and its applications.
Vitamins 8h
Classification and Nomenclature of vitamins. Fat soluble vitamins and water-soluble vitamins Sources,
deficiency diseases, Vitamin B complex and Vitamins of E group. Structure of Vitamin A1andA2,
mechanism of vision, structures of Vitamin B1, Vitamin C, Vitamin D, Vitamin E & Vitamin K1.

LAB 8; Chemistry Practicals-VIII:

Inorganic and Biological Chemistry Practicals
INORGANIC CHEMISTRY PRACTICALS
1. Preparation of cis and trans-potassiumdioxalatodiaquachromium (III) complex
2. Preparation of cuprammoniumsulphate.
3. Preparation of tri-oxalato ferrate(III).
4. Preparation of hexamminecobalt(III) chloride.
5. Preparation of pentaamminecobalt(III) chloride.

BIOLOGICAL CHEMISTRY PRACTICALS

1. Estimation of ɑ-amino acids using ninhydrin by colorimetric method.
2. Determination of blood group.
3. Separation of ɑ-amino acids by paper chromatography.

26
 4. Isolation of DNA from onions.
5. Estimation of cholesterol by colorimetric method.
6. Determination of pKa of amino acid (glycine).
7. Qualitative analysis of carbohydrates.

Pedagogy:
Practically learning; Assignments; Seminars/ Presentations; Viva-voce;
Quiz; ICT (online) learning.

Course Articulation Matrix:

Mapping of Course Outcomes (COs) with Program Outcomes (POs 1-12)
Course Articulation Matrix relates course outcomes of course with the corresponding
program outcomes whose attainment is attempted in this course. Mark ‘X’ in the
intersection cell if a course outcome addresses a particular program outcome.

COs \ POs 1 2 3 4 5 6 7 8 9 1 1 1
0 1 2

CO 1 3 2 3 2 1 3 3 2 3 1 1

CO 2 2 2 2 2 3 3 1 3 2 1

CO 2 3 2 2 3 1 2 1 1

CO 3 3 3 2 3 1 3 2 2 3 1

CO 3 3 3 2 3 1 3 2 2 1 1

Note: H = 3 ; M = 2; and L = 1.

REFERENCES (Theory)
1. Advanced Inorganic Chemistry, 6th Edition F. A. Cotton, G. Wilkinson, C. A. Murillo and M.
Bochmann-John Wiley & Sons, 1999.
2. Concise Inorganic Chemistry, 5th Edition J. D. Lee, Blackwell Science, 2001.
3. Inorganic Chemistry, 4th Edition J. E. Huhee, E. A. Keiter and R. I. Keiter, Pearson Education
Asia, 2000
4. Inorganic Chemistry, ELBS 2nd Edition D. F. Shriver, P. W. Atkins and C. H. Langford,
27
 Oxford Univ. Press 2002.
5. Modern Inorganic Chemistry W. L. Jolly, McGraw Hill Co.
6. Principles of Inorganic Chemistry B. R. Puri and L. R. Sharma, Jauhar S. P-S. N. Chand & Co.,
1998
7. Inorganic Chemistry, 3rd Edition (ISE) A G Sharpe, Addison Wesley, 1989.
8. Basic Inorganic Chemistry, 3rd Edition F. A. Cotton, G. Wilkinson, P. L. Gaus-John Wiley &
Sons, 1995.
9. Essential Chemistry, International Edition R. Chang, McGraw Hill Co, 1996.
10. University Chemistry, 4th Edition (ISE) B. H. Mahan & R. J. Myers, Addison Wesley, 1989.
11. Essential Trends in Inorganic Chemistry C. M. P. Mingos, Oxford Univ Press, 1998
12. Chemistry, 3rd Edition P. Atkins & L.Jones, W. H. Freeman & Company, 1997.
13. Modern Chemistry, 4th Edition D. W. Oxicby, H. P. Gills & N. H. Nachtrieb, Saunders College
Publishing, 1998.
14. Concise Textbook of Biochemistry T. N. Pattabhiraman, All India Publishers, 2000.
15. Biochemistry A. L. Lehningeret. al., CBS, 2000.
16. A Textbook of Biochemistry A. V. S. S. Rama Rao, UBSPD, 1998.
17. Biochemistry P. C. Champe and R. A. Harvey, J. B. Lipincott& Co, 1982.
18. Fundamentals of Biochemistry J. L. Jain, S. Chand & Co., 1983.
19. Biochemistry COSIP -ULP, Bangalore University, 1981.Outlines of Biochemistry Conn E. E
and Stumpf P. K., John Wiley & Sons, 1978.

(Practicals)
1. Vogel's Textbook of Qualitative Chemical Analysis, J. Bassett, G. H. Jeffery and J. Mendham,
ELBS (1986).
2. Vogel's textbook of Quantitative Chemical Analysis, 5th Edition, J. Bassett, G. H. Jeffery and
J. Mendham, and R. C. Denny, Longman Scientific and Technical (1999).
3. Inorganic Semimicro Qualitative Analysis, V. V. Ramanujam; The National Pub. Co. (1974).
4. Practical Inorganic Chemistry, G. Marr and B. W. Rockett, Von Nostrand Reinhold Co.,
London (1972).

28
ASSESSMENT: WEIGHTAGE FOR ASSESSMENT
Common for both V and VI semesters

TYPE SUMMATI FORMATI

O VE VE
F (MARKS) (MARKS)
ASSESSMENT

THEORY 60 40

PRACTICAL 25 25

SCHEME OF INTERNAL
ASSESSMENT MARKS: THEORY
PAPERS
Common for both V and VI semesters

Sl N PARTICULARS MARKS

1 Attendance 10

2 Assignments/ Seminars 10

3 Internal Tests (Average of two 20

tests)

TOTAL 40

PRACTICALS
Common for both V and VI semesters

SL PARTICULARS MARKS
NO

1 Attendance 05

2 Record writing 05

3 Internal Tests (Average of two 15

tests)

TOTAL 25

29
END PAGE

30