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    CDC, December 2022

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    pamela
    The US Public Health Service conducted an experiment from 1932 to 1972 to study untreated syphilis in African American men without their informed consent. Over 600 men were involved, some with syphilis and some without. The men were told they were being treated for "bad blood" but were not given proper treatment even after penicillin became the standard in 1943. Many men died from syphilis and other diseases, and some passed syphilis to their offspring. This unethical study led to the National Research Act of 1974 and the Belmont Report, which established ethical principles of beneficence, respect for persons, and justice in human subjects research.

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    CDC, December 2022

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    pamela
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    The US Public Health Service conducted an experiment from 1932 to 1972 to study untreated syphilis in African American men without their informed consent. Over 600 men were involved, some with syphilis and some without. The men were told they were being treated for "bad blood" but were not given proper treatment even after penicillin became the standard in 1943. Many men died from syphilis and other diseases, and some passed syphilis to their offspring. This unethical study led to the National Research Act of 1974 and the Belmont Report, which established ethical principles of beneficence, respect for persons, and justice in human subjects research.

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    The US Public Health Service conducted an experiment from 1932 to 1972 to study untreated syphilis in African American men without their informed consent. Over 600 men were involved, some with syphilis and some without. The men were told they were being treated for "bad blood" but were not given proper treatment even after penicillin became the standard in 1943. Many men died from syphilis and other diseases, and some passed syphilis to their offspring. This unethical study led to the National Research Act of 1974 and the Belmont Report, which established ethical principles of beneficence, respect for persons, and justice in human subjects research.

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    Download as docx, pdf, or txt
    11 views2 pages

    CDC, December 2022

    Uploaded by

    pamela
    The US Public Health Service conducted an experiment from 1932 to 1972 to study untreated syphilis in African American men without their informed consent. Over 600 men were involved, some with syphilis and some without. The men were told they were being treated for "bad blood" but were not given proper treatment even after penicillin became the standard in 1943. Many men died from syphilis and other diseases, and some passed syphilis to their offspring. This unethical study led to the National Research Act of 1974 and the Belmont Report, which established ethical principles of beneficence, respect for persons, and justice in human subjects research.

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    (CDC, December 2022)This experiment was carried out by the US Public Health Service

    (PHS)to test treatment for syphilis. African American were used for this experiment. The
    researchers had told them that they were being treated for bad blood’ which included
    anemia, fatigue, and syphilis. In total, it consisted of 600 men, 201 did not have syphilis,
    while 399 had it. The US PHS failed to collect informed consent, and the men did not
    know it was an experiment being carried out. In return for their participation, they were
    told that they would receive funeral/burial insurance, free meals, and free medical
    exams. Many people died from the syphilis infection and other diseases and even
    passed on congenital syphilis to their offspring. This resulted from the fact that Penicillin
    was the treatment of choice by 1943, however the men who took part in the study
    weren’t offered treatment. This led to a press story being published in 1972 about the
    study and what occurred during the study. It was found to be unethical as the risks
    involved on human subjects were known but not disclosed. Thus, the National Research
    Act was created by the National Commission for the Protection of Human Subjects of
    Biomedical and Behavioral Research. The Belmont Report was written by the
    commission which summarized the ethical principles that would guide human research.
    the principles as listed below:

     Beneficence: Researchers should check to ensure that the benefits outweigh the
    risks of the experiment and possible harm should be minimized.
     Respect for persons: all people should be treated as autonomous agents and
    any people with diminished autonomy are entitled to be protected (people who
    for example have dementia, illiterate people or people who cannot think for
    themselves).
     Justice: This states that all people should be treated with justice, equally and the
    selection of participants for research should be checked carefully so that the
    selection is not based on race, ethnicity, or class.
    This regulatory change was a pivotal point in medicine as the issues of unfair treatment
    due to race or class were addressed. This also led to ensuring that people who choose
    to take part in the clinical trials or studies know exactly what they are getting into, and
    the risks involved in the study. There is clear baseline communication between
    participants and researchers on what the study is about, what it entails etc. The
    selection criteria is also diverse and not just limited to a group or certain race.
    Everything is standardized.

    References
    CDC, (December 2022). The Untreated Syphilis Study at Tuskegee Timeline. 2.

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