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    Hematology KBMD 10.02.24

    Uploaded by

    Dr Nikita N
    The document contains multiple questions related to hematology. It asks the reader to identify blood cells, laboratory tests that would decrease in iron deficiency anemia, which blood component would be normal in polycythemia vera, which test can determine the cause of an abnormal blood smear, and the most likely underlying diagnosis for a girl with mucosal bleeding and low blood counts.

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    Hematology KBMD 10.02.24

    Uploaded by

    Dr Nikita N
    32 views25 pages
    The document contains multiple questions related to hematology. It asks the reader to identify blood cells, laboratory tests that would decrease in iron deficiency anemia, which blood component would be normal in polycythemia vera, which test can determine the cause of an abnormal blood smear, and the most likely underlying diagnosis for a girl with mucosal bleeding and low blood counts.

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    hematology kbmd 10.02.24

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    The document contains multiple questions related to hematology. It asks the reader to identify blood cells, laboratory tests that would decrease in iron deficiency anemia, which blood component would be normal in polycythemia vera, which test can determine the cause of an abnormal blood smear, and the most likely underlying diagnosis for a girl with mucosal bleeding and low blood counts.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    32 views25 pages

    Hematology KBMD 10.02.24

    Uploaded by

    Dr Nikita N
    The document contains multiple questions related to hematology. It asks the reader to identify blood cells, laboratory tests that would decrease in iron deficiency anemia, which blood component would be normal in polycythemia vera, which test can determine the cause of an abnormal blood smear, and the most likely underlying diagnosis for a girl with mucosal bleeding and low blood counts.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 25

    HEMATOLOGY

    KBMD
    Medsynapse by Dr . Nikita
    Identify the blood cell
    a) Neutrophil
    b) Basophil
    c) Eosinophil
    d) Monocyte

    Medsynapse by Dr. Nikita


    All of the following decrease in iron deficiency
    anemia except

    a) Transferrin saturation
    b) Serum ferritin
    c) TIBC
    d) Serum iron

    Medsynapse by Dr. Nikita


    A blood sample from a patient with polycythemia
    vera is sent for complete blood count. Which of the
    following blood components is most likely to be
    reported within normal limits?
    (A) Lymphocytes
    (B) Neutrophils
    (C) Platelets
    (D) Red blood cells
    (E) White blood cells

    Medsynapse by Dr. Nikita


    A 43-year-old man presents to his physician with fatigue. The patient
    says he is concerned about his fatigue because he has a strong family
    history of ‘cancer. He thinks that if his parents did not drink, smoke,
    and eat such poor diets they would have lived longer lives. He says
    that because of all this, he never drinks alcohol or smokes tobacco.
    He has also followed a strict vegan diet for 10 years. He says that all
    of his meals are high in leafy green vegetables. Laboratory tests show
    a hematocrit of 35% with a normal RBC distribution width. Results of
    a peripheral blood smear are shown in the image. Which of the
    following laboratory tests will most definitively determine the likely
    cause of his abnormal blood smear?
    A. Folate level
    B. Homocysteine level
    C. Methylmalonic acid level
    D. Serum gastrin levels
    E. Urine vitamin B12 level
    Medsynapse by Dr. Nikita
    A 13 year old girl has mucosal bleeding and petechial rashes. She has
    been feeling tired lately. She looks pale. A blood count shows:
    Haemoglobin 74 g/L White cell count 1.9 x 109 /L
    Neutrophils 0.1 x 109 /L Platelets 24 x 109 /L
    Blood film morphology was unremarkable. Reticulocytes are absent. A
    bone marrow aspirate shows a gross reduction in all haematopoietic
    tissue that is replaced by fat spaces. What is the SINGLE most likely
    underlying diagnosis?

    A. Pernicious anaemia
    B. Chronic myeloid leukaemia
    C. Aplastic anaemia
    D. Acute myeloid leukaemia
    E. Acute lymphoblastic leukaemia
    Medsynapse by Dr. Nikita
    A 23-year-old African American woman presents to
    the emergency department with severe abdominal
    pain and evidence of dehydration. Her past medical
    history is significant for numerous pulmonary
    infections and effusions of the knees. This patient’s
    erythrocytes would be expected to exhibit

    (A) an absence of central pallor


    (B) deletion of all four alpha Hb genes
    (C) denaturation during deoxygenation
    (D) Heinz bodies on RBC staining

    Medsynapse by Dr. Nikita


    A 27-year-old woman, gravida 2, para 1, at 26 weeks' gestation comes to the
    emergency department because of vaginal bleeding and epistaxis for the past 2
    days. She missed her last prenatal visit 2 weeks ago. Physical examination
    shows blood in the posterior pharynx and a uterus consistent in size with 23
    weeks' gestation. Her hemoglobin concentration is 7.2 g/dL. Ultrasonography
    shows an intrauterine pregnancy with a small retroplacental
    hematoma and absent fetal cardiac activity. Further evaluation is most likely to
    show which of the following findings?

    A Decreased prothrombin time


    B Increased factor V concentration
    C Decreased partial thromboplastin time
    D Decreased fibrinogen concentration
    A 22-year-old man presents to the emergency department
    With mucosal bleeding and epistaxis. Laboratory tests
    Show an increased bleeding time and an increased partial
    thromboplastin time. His mother was anemic throughout
    her life and required several blood transfusions after a
    minor operation.
    Which of the following is the most likely diagnosis?

    A. Bernard-Soulier syndrome
    B. Glanzmann disease
    C. Hemophilia A
    D. Vitamin K deficiency
    E. Von Willebrand disease

    Medsynapse by Dr. Nikita


    Medsynapse by Dr. Nikita
    A 68-year-old man comes to the physician because of a 6-month history of progressive
    headache, dizziness, and weakness. Hot showers cause generalized pruritus. He had a normal
    routine health examination 5 years ago, at which point routine laboratory studies were also
    normal. His pulse is 90/min and blood pressure is 150/88 mm Hg. Physical examination
    shows facial plethora. Examination of the heart and lungs shows no abnormalities. The
    spleen is palpable 2 cm below the left costal margin. Genetic analysis shows a mutation in
    the JAK2 gene. Which of the following sets of findings is the most likely in this patient?

    EPO levels Plasma volume RBC mass SaO2

    a Normal decreased normal normal


    b Increased normal increased decreased
    c Decreased increased increased normal
    d Decreased normal normal normal
    Seen in myelofibrosis

    a) Bite cells
    b) Burr cells
    c) Dacrocytes
    d) Target cells

    Medsynapse by Dr. Nikita


    Medsynapse by Dr. Nikita
    Medsynapse by Dr. Nikita
    A patient has a lymphoproliferative disorder
    containing mature B cells that mark weakly with
    kappa light chain on the plasma membrane, strongly
    with CD5, strongly with CD23, and weakly with
    CD22. Which of the following is the most likely
    diagnosis?
    (A) Chronic lymphocytic leukemia
    (B) Hairy cell leukemia
    (C) Non-Hodgkin lymphoma
    (D) Prolymphocytic leukemia
    (E) Sézary syndrome

    Medsynapse by Dr. Nikita

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