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    Lecture 7

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    jumanah.buzlouf
    This document contains a test bank of 14 multiple choice pharmacology questions with answers. The questions cover topics like: - Receptors and how drugs bind to them - Agonists, antagonists, and competitive vs non-competitive antagonists - Selective serotonin reuptake inhibitors and how they work - The definition of pharmacodynamics and what it involves - The definition of terms like "receptor", "affinity", and targets that drugs can bind to - Examples of ion channel blocking drugs - The type of drug-drug interaction that occurs at the receptor, cell, enzyme or organ level

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    Lecture 7

    Uploaded by

    jumanah.buzlouf
    19 views4 pages
    This document contains a test bank of 14 multiple choice pharmacology questions with answers. The questions cover topics like: - Receptors and how drugs bind to them - Agonists, antagonists, and competitive vs non-competitive antagonists - Selective serotonin reuptake inhibitors and how they work - The definition of pharmacodynamics and what it involves - The definition of terms like "receptor", "affinity", and targets that drugs can bind to - Examples of ion channel blocking drugs - The type of drug-drug interaction that occurs at the receptor, cell, enzyme or organ level

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    This document contains a test bank of 14 multiple choice pharmacology questions with answers. The questions cover topics like: - Receptors and how drugs bind to them - Agonists, antagonists, and competitive vs non-competitive antagonists - Selective serotonin reuptake inhibitors and how they work - The definition of pharmacodynamics and what it involves - The definition of terms like "receptor", "affinity", and targets that drugs can bind to - Examples of ion channel blocking drugs - The type of drug-drug interaction that occurs at the receptor, cell, enzyme or organ level

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    19 views4 pages

    Lecture 7

    Uploaded by

    jumanah.buzlouf
    This document contains a test bank of 14 multiple choice pharmacology questions with answers. The questions cover topics like: - Receptors and how drugs bind to them - Agonists, antagonists, and competitive vs non-competitive antagonists - Selective serotonin reuptake inhibitors and how they work - The definition of pharmacodynamics and what it involves - The definition of terms like "receptor", "affinity", and targets that drugs can bind to - Examples of ion channel blocking drugs - The type of drug-drug interaction that occurs at the receptor, cell, enzyme or organ level

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    Pharmacology

    Test Bank
    Done By: Lujain AL-Ashhab
    Lecture 7
    Q1: the wrong statement of the following regarding
    receptors and drugs:
    a) most of the receptors are proteins
    b) most drugs bind irreversibly (covalent)
    c)not all drugs use receptors.
    d) receptors determine specificity of drug action
    ANSWER: B

    Q2: when the drug itself did not initiate a signaling cascade, it just Prevented the
    endogenous ligand from initiating its own endogenous cascade , then this drug is:
    a) Agonist
    b) Reverse agonist
    c) Antagonist
    d) B+C
    ANSWER:C

    Q3: Antagonists are considered as non -competitive when:


    a)the binding to the binding site of receptors is irreversible
    b)the binding to their receptors is reversible
    c) the binding is to a remote site ,causing allosteric effect
    d)more than one answer are true
    ANSWER:D

    Q4: In order to treat depression, selective serotonin reuptake inhibitors (fluoxetine)are


    given to prevent the :
    a) rapid uptake of serotonin to stay longer time in the synapse
    b) Signal transduction proteins inhibitors
    c) Enzymes inhibitors
    d) Ion channels blockers
    e) Transport inhibitors
    ANSWER:D

    Q5 : Pharmacodynamics involves the study of following EXCEPT:


    a) Biological and therapeutic effects of drugs
    b) Absorption and distribution of drugs
    c) Mechanisms of drugs action
    d) Drug interactions
    ANSWER:B
    Q6 : Pharmacodynamics involves the study of following ?
    a) mechanisms of drug action
    b) Biotransformation of drugs in the organism
    c)Distribution of drugs in the organism
    d)Excretion of drug from the organism
    ANSWER: A

    Q7 :Pharmacodynamics involves the study of following ?


    a)information about main mechanisms of drug absorption
    b)information about unwanted effects
    c)information about biological barriers
    d) information about excretion of a drug from the organism
    Answer : B

    Q8 : Pick out the answer which is the most appropriate to the term “receptor “
    a)All types of ion channels modulated by a drug
    b) Enzymes of ox iodizing -reducing reactivate ed a drug
    c) Active macromolecular components of a cell or an organ ism which a drug
    molecule has to combine with in order to elicit its specific effect.
    d) Carriers activated by a drug
    Answer :c

    Q9 : What does “affinity “ mean ?


    a) A measure of how tightly a drug binds to plasma proteins
    b) A measure of how tightly a drug binds to a receptor
    c) A measure of inhibiting potency of a drug
    d) A measure of bioavailability of a drug
    Answer : B

    Q10 : Target proteins which a drug molecule binds are :


    a) Only receptors
    b) Only ion channels
    c) Only carriers
    d) All of the above
    Answer :D
    Q11 : An agonist is a substance that :
    a) Interacts with the receptor without producing any effect
    b) Interacts with the receptor and initiates changes in cell function ,producing
    various effects
    c) In creases con centration of another substance to produce effect
    d) Interacts with plasma proteins and doesn’t produce any effect
    Answer : B

    Q12: Irreversible interaction of an antagonist with a receipt or due to :


    a) Ionic bonds
    b) Hydrogen bonds
    c) covalent bonds
    d) All of the above
    Answer: c

    Q13: Tick the substances whose mechanisms are based on interaction with ion channels
    a) sodium channel blockers
    b) calcium channel blockers
    c) potassium channel activators
    d)All of the above
    Answer : D

    Q14: What is the type of drug to drug interaction which is the result of interaction at
    receptor, cell, enzyme or organ level ?
    a) Pharmacodynamic interaction
    b) Physical and chemical interaction
    c) Pharmaceutical interaction
    d) Pharmacokinetic interaction
    Answer : A

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