PharmCal Chapters 13

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UNIVERSITY OF SOUTHERN MINDANAO

CHAPTER 13:
IV INFUSION, PARENTERAL
ADMIXTURES, AND RATE-FLOW
CALCULATION
Prepared by:
JOHN ERIC TANDOG MARIANO, RPh.
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INJECTION
▪ Sterile pharmaceutical solutions or suspension of a drug
substance in an aqueous or nonaqueous vehicle
▪ IO, IS, Intraspinal, IT, IA, IC, IV, IM, ID, SQ.
▪ Packed in small volumes in ampuls or
▪ prefilled disposable syringes for single–dose use
▪ Vials and pen-injectors for single and multiple dose use
▪ Plastic bags or glass containers for large volume
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INTRAVENOUS INFUSIONS
▪ IVPB
▪ Small IV bag attached to larger IV bag
▪ LVP
▪ Large Volume Parenteral
▪ SVP
▪ Small-volume Parenteral
▪ Administration Set
▪ Macrodrip - 10 to 15 gtt/mL
▪ Microdrip – 60 gtt/mL
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INTRAVENOUS INFUSIONS
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INTRAVENOUS INFUSIONS
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INTRAVENOUS INFUSIONS
How many grams each of dextrose and sodium chloride
are used to prepare a 250-mL bag of D5½N S for
intravenous infusion?
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INTRAVENOUS INFUSIONS
Calculate the milliequivalents of sodium and millimoles
of dextrose in the above solution.
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INFUSION ADMINISTRATION SETS


Calculate the total drops in the delivery o 250 mL o an
infusion when using the following administration sets:
(a) 15 drops/mL,
(b) 20 drops/mL, and
(c) 60 mcgtts/mL.
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

IVP DRUG ADMINISTRATION


▪ Critical or Emergency situation
▪ Control HR, BP, CO, RR, and others
▪ Administered in a short time frame (From <1 to 5
minutes)
▪ Safety: Less concentrated solution
▪ Directly or indirectly Administration of bolus dose
▪ Secondary injection (flush) – NSS, to help
medication to reach the blood stream and to clean
infusion line before and/or after use.
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

IVP DRUG ADMINISTRATION


A physician orders enalaprilat (VASOTEC IV) 2 mg IVP
for a hypertensive patient. A pharmacist delivers several
1-mL injections, each containing 1.25 mg of enalaprilat.
How many milliliters of the injection should be
administered?
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

IVP DRUG ADMINISTRATION


General guidelines in the treatment of severe diabetic
ketoacidosis include an initial bolus dose of 0.1 to 0.4
unit of insulin/kg IVP, followed by an insulin drip.
Calculate the bolus dosage range for a 200-lb patient
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

PEDIATRIC INFUSIONS
Calculate the daily infusion volume of D10W to be
administered to a neonate weighing 3 lb. 8 oz. on the
basis of 60 mL/kg/day.
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

RATE FLOW OF IV FLUIDS


CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

RATE FLOW
OF IV FLUIDS
CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INFUSION RATE TABLE


CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

INFUSION RATE TABLE


CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

mAbs Infusion Calculation


CHAPTER 13: IV INFUSION, PARENTERAL ADMIXTURES, AND RATE-
FLOW CALCULATION

ASSIGNMENT:

PLEASE ANSWER CHAPTER 13 PRACTICE


PROBLEMS Nos. 1, 3, 7, 9, 50, 54, 68.

Submission: December 5, 2023 (TUESDAY), 10am


Reference

Book: Pharmaceutical Calculations 15th Edition


by Howard C. Ansel, Ph.D

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