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    A Level Homework 5

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    szyzyp
    (1) Monoclonal antibodies are antibodies that are identical and recognize a single epitope. They are used in medical treatments such as cancer immunotherapy. Antibodies play a role in ELISA tests by binding to antigens, which produces a detectable signal if antigens are present. (2) A malaria test strip uses monoclonal antibodies to determine if a person is infected with Plasmodium falciparum or Plasmodium vivax. Antibody A binds to a protein common to both species. The test results show the person is infected with P. falciparum since only antibody C produced a positive result, indicating the presence of a protein unique to that species.

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    A Level Homework 5

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    szyzyp
    25 views4 pages
    (1) Monoclonal antibodies are antibodies that are identical and recognize a single epitope. They are used in medical treatments such as cancer immunotherapy. Antibodies play a role in ELISA tests by binding to antigens, which produces a detectable signal if antigens are present. (2) A malaria test strip uses monoclonal antibodies to determine if a person is infected with Plasmodium falciparum or Plasmodium vivax. Antibody A binds to a protein common to both species. The test results show the person is infected with P. falciparum since only antibody C produced a positive result, indicating the presence of a protein unique to that species.

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    A level biology homework pack

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    A level homework 5

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    (1) Monoclonal antibodies are antibodies that are identical and recognize a single epitope. They are used in medical treatments such as cancer immunotherapy. Antibodies play a role in ELISA tests by binding to antigens, which produces a detectable signal if antigens are present. (2) A malaria test strip uses monoclonal antibodies to determine if a person is infected with Plasmodium falciparum or Plasmodium vivax. Antibody A binds to a protein common to both species. The test results show the person is infected with P. falciparum since only antibody C produced a positive result, indicating the presence of a protein unique to that species.

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    Download as rtf, pdf, or txt
    25 views4 pages

    A Level Homework 5

    Uploaded by

    szyzyp
    (1) Monoclonal antibodies are antibodies that are identical and recognize a single epitope. They are used in medical treatments such as cancer immunotherapy. Antibodies play a role in ELISA tests by binding to antigens, which produces a detectable signal if antigens are present. (2) A malaria test strip uses monoclonal antibodies to determine if a person is infected with Plasmodium falciparum or Plasmodium vivax. Antibody A binds to a protein common to both species. The test results show the person is infected with P. falciparum since only antibody C produced a positive result, indicating the presence of a protein unique to that species.

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    of 4

    Homework 5- Paper 1 revision Monoclonal antibodies and Elisa test

    Q1.
    (a) What is a monoclonal antibody?

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    (1)

    (b) After a disease is diagnosed, monoclonal antibodies are used in some medical
    treatments.

    Give one example of using monoclonal antibodies in a medical treatment.

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    (1)

    (c) Describe the role of antibodies in producing a positive result in an ELISA test.

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    (4)
    (Total 6 marks)

    Page 1 of 4
    Q2.
    Malaria is a disease caused by parasites belonging to the genus Plasmodium. Two
    species that cause malaria are Plasmodium falciparum and Plasmodium vivax.

    A test strip that uses monoclonal antibodies can be used to determine whether a person is
    infected by Plasmodium. It can also be used to find which species of Plasmodium they are
    infected by.

    • A sample of a person’s blood is mixed with a solution containing an antibody, A, that


    binds to a protein found in both species of Plasmodium. This antibody has a
    coloured dye attached.
    • A test strip is then put into the mixture. The mixture moves up the test strip by
    capillary action to an absorbent pad.
    • Three other antibodies, B, C and D are attached to the test strip. The position of
    these antibodies and what they bind to is shown in Figure 1.

    Figure 1

    (a) Explain why antibody A attaches only to the protein found in species of
    Plasmodium.

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    (2)

    (b) Antibody B is important if this test shows a person is not infected with Plasmodium.

    Explain why antibody B is important.

    Page 2 of 4
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    (2)

    (c) One of these test strips was used to test a sample from a person thought to be
    infected with Plasmodium. Figure 2 shows the result.

    Figure 2

    What can you conclude from this result?

    Explain how you reached your conclusion.

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    (4)
    (Total 8 marks)

    Page 3 of 4
    Page 4 of 4

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