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Cambridge IGCSE™

BIOLOGY 0610/22
Paper 2 Multiple Choice (Extended) February/March 2023
45 minutes

You must answer on the multiple choice answer sheet.

*7012350775*

You will need: Multiple choice answer sheet

Soft clean eraser
Soft pencil (type B or HB is recommended)

INSTRUCTIONS
• There are forty questions on this paper. Answer all questions.
• For each question there are four possible answers A, B, C and D. Choose the one you consider correct
and record your choice in soft pencil on the multiple choice answer sheet.
• Follow the instructions on the multiple choice answer sheet.
• Write in soft pencil.
• Write your name, centre number and candidate number on the multiple choice answer sheet in the
spaces provided unless this has been done for you.
• Do not use correction fluid.
• Do not write on any bar codes.
• You may use a calculator.

INFORMATION
• The total mark for this paper is 40.
• Each correct answer will score one mark.
• Any rough working should be done on this question paper.

This document has 16 pages. Any blank pages are indicated.

IB23 03_0610_22/5RP
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1 What is used as a means of classification?

A the number of strands of mRNA

B the shape of DNA molecules
C the sequence of bases in DNA
D the types of bases in DNA

2 How many jointed legs does an insect have?

A two pairs
B three pairs
C four pairs
D more than six pairs

3 The photomicrograph shows a cell from a type of aquatic plant.

R Q P

Which labelled parts indicate that this is a plant cell?

A P and R B P and S C Q and R D Q and S

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4 The diagram shows a red blood cell.

49 mm

The actual diameter of the cell is 7.0 micrometres.

What is the magnification of this cell?

A ×70 B ×700 C ×7000 D ×70 000

5 Which molecule crosses a partially permeable membrane during osmosis?

A carbon dioxide
B oxygen
C urea
D water

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6 The graph shows the rate of uptake of magnesium ions by two similar plants, X and Y.

The roots of each plant were placed in a range of solutions. Each solution contained a different
concentration of magnesium ions. All other conditions were kept constant.

plant X

rate of uptake of
magnesium ions
plant Y

concentration of magnesium
ions in external solution

What is a possible explanation for the difference in the results for the two plants?

A Plant Y has fewer protein carriers for magnesium ions in its cell membranes.
B Plant Y has a higher rate of respiration.
C Plant Y has more root hair cells.
D The root hair cells in plant Y have a lower water potential.

7 Which substance is used to test a food for vitamin C?

A Benedict’s solution
B DCPIP
C ethanol
D iodine solution

8 In DNA, what is the correct base pairing?

A T with C B T with T C T with G D T with A

9 What remains at the end of an enzyme-controlled reaction?

A enzymes and products

B enzymes and substrates
C enzymes only
D products only

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10 Which feature explains the specificity of an enzyme?

A complementary shape of active site and substrate

B denaturation at certain pH values
C temperature change leading to change in enzyme activity
D varying frequency of effective collisions between enzyme and substrate

11 A plant is placed in the dark until all its stored starch is used up. The plant is placed in light with
black paper over part of one green leaf.

black paper over

both sides of the leaf

hole cut in the paper

After eight hours, the leaf is tested for starch.

Which diagram shows the appearance of the leaf after this test?

A B

key

= starch
present
C D
= starch not
present

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12 The diagram shows part of a cross-section of a leaf.

Which row shows the correct labels?

R S T

A cuticle palisade mesophyll spongy mesophyll

B cuticle spongy mesophyll palisade mesophyll
C epidermis palisade mesophyll spongy mesophyll
D epidermis spongy mesophyll palisade mesophyll

13 The diagrams show the different types of human teeth.

1 2 3 4

Which teeth are used for grinding food?

1 2 3 4

A     key
B     = yes
C     = no
D    

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14 The diagram shows a villus. Structures P and Q absorb different products of digestion.

P
Q

Which row identifies the products absorbed by P and Q?

P Q

A amino acids glucose

B fatty acids maltose
C glucose fatty acids
D maltose amino acids

15 The arrows show the movement of substances from the soil into a root hair cell.

Which substances move from the soil into the root hair cell?

A carbon dioxide and oxygen

B glucose and water
C mineral ions and glucose
D water and mineral ions

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16 By which process does water escape from stomata in the leaves?

A active transport
B diffusion
C evaporation
D osmosis

17 Which row about the circulatory system is correct?

part that pumps blood part with valves

A heart heart and veins

B heart and blood vessels all blood vessels
C capillaries heart
D heart capillaries and arteries

18 The graph shows pressure changes that take place in the right atrium, right ventricle and left
ventricle of a human heart when the muscle walls contract and relax.

16

14

12

10
pressure
8
/ kPa

0
0.0 0.2 0.4 0.6
time / s

What is the pressure in the right ventricle when the left ventricle is at its maximum pressure?

A 0.4 kPa B 2.0 kPa C 3.0 kPa D 15.0 kPa

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19 The sequence of amino acids in antibodies enables them to complete which function?

A bind to a specific antigen

B bind to all pathogens
C perform phagocytosis
D confer passive immunity for all diseases

20 The table shows some of the changes that occur during breathing.

from contracted from relaxed

to relaxed to contracted

diaphragm P X
external intercostal muscles Q Y
internal intercostal muscles R Z

Which changes occur to cause inspiration?

A P, Q and Z B X, Q and R C X, Y and R D X, Y and Z

21 The apparatus shown was used to investigate aerobic respiration in seeds.

The apparatus was placed in a dark room.

wire mesh ruler

coloured liquid
seeds soaked chemical which
in water absorbs the gas
produced by
the seeds

All environmental conditions were kept constant.

What will happen in the apparatus?

gas absorbed direction of

gas taken in
by the chemical movement of the
by the seeds
in the wire mesh coloured liquid

A carbon dioxide oxygen towards the seeds

B carbon dioxide oxygen away from the seeds
C oxygen carbon dioxide towards the seeds
D oxygen carbon dioxide away from the seeds

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22 Why is yeast used in bread-making?

A Aerobic respiration produces alcohol.

B Aerobic respiration produces lactic acid.
C Anaerobic respiration produces alcohol.
D Anaerobic respiration produces carbon dioxide.

23 In the diagram, which label identifies the urethra?

A
B

24 The diagram shows a reflex arc.

Which label identifies the motor neurone?

finger pricked
by pin
D

A
C
B

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25 Which structures contain neurotransmitter molecules in neurones?

A chloroplasts
B mitochondria
C ribosomes
D vesicles

26 The diagram shows a seedling growing inside a dark box.

dark box

shoot

root

Which type of responses affect the direction of growth of the root and the shoot inside the box?

response response
by the root by the shoot

A gravitropism gravitropism
B gravitropism phototropism
C phototropism gravitropism
D phototropism phototropism

27 Why is an MRSA infection difficult to treat?

A MRSA is a bacterium.
B MRSA is a virus.
C MRSA is resistant to some antibiotics.
D MRSA is resistant to some antibodies.

28 What is the order of flower parts through which the pollen tube must grow to reach the egg cell
nucleus during fertilisation?

A stigma → style → ovule → ovary

B stigma → style → ovary → ovule

C style → stigma → ovule → ovary

D style → stigma → ovary → ovule

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29 Which diagram, showing the exchange of products between mother and fetus, is correctly
labelled?

A B
placenta umbilical cord
waste waste
products products
nutrients nutrients

umbilical placenta
cord

C D
umbilical cord placenta
nutrients nutrients

waste waste
products products

placenta umbilical
cord

30 Which statement about the synthesis of a protein molecule in a cell is correct?

A The gene coding for the protein moves from nucleus to cytoplasm.
B Ribosomes assemble amino acids into DNA molecules.
C mRNA remains in the nucleus.
D The sequence of amino acids is determined by the sequence of bases in the mRNA.

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31 Each statement describes cell division by mitosis or meiosis in humans.

1 It produces cells that show variation.

2 It produces cells that are diploid.
3 It produces cells that are haploid.
4 It involves reduction division.

Which statements describe meiosis?

1 2 3 4

A     key
B     = yes
C     = no
D    

32 In humans, what is the genotype of a red-green colour-blind male?

A XRXR B XrXr C XRY D XrY

33 Which feature is found in a hydrophytic plant?

A Leaves are curled with stomata on the inside.

B Leaves are reduced to spines.
C Stomata are sunk in pits in the epidermis.
D There is no waxy cuticle.

34 Which statements are correct during both natural selection and artificial selection?

1 Only certain individuals reproduce.

2 Alleles are passed on to the offspring.
3 Organisms do not compete with each other for survival.

A 1 and 2 B 1 and 3 C 2 only D 2 and 3

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35 The diagram shows a food chain.

phytoplankton → zooplankton → herring → sea lion

Which diagram shows a pyramid of energy for this food chain?

A B
sea lion phytoplankton

herring zooplankton

zooplankton herring

phytoplankton sea lion

C D

sea lion phytoplankton

herring zooplankton

zooplankton herring

phytoplankton sea lion

36 In the nitrogen cycle, what are processes 1 and 2?

nitrogen in
1 atmosphere

plant animal 2
protein protein

nitrates
in soil

process 1 process 2

A decomposition nitrification
B denitrification nitrogen fixation
C nitrification evaporation
D nitrogen fixation denitrification

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37 Untreated sewage is accidently released into a river for several weeks.

How will this affect the number of bacteria, the oxygen concentration of the water and the number
of fish?

number of oxygen
number of fish
bacteria concentration

A decrease decrease increase

B increase decrease decrease
C decrease increase decrease
D no change no change no change

38 Fish stocks can be conserved in various ways.

Which method of conservation ensures that mainly large fish are caught?

A having closed seasons

B having protected areas
C having a minimum mesh size for nets
D setting legal fishing quotas

39 Which component of bacteria is genetically modified to produce human insulin?

A cell membrane
B cell wall
C plasmids
D single circular DNA strand

40 Fermenters must have carefully controlled conditions.

Which condition has the correct reason for controlling it?

condition to be controlled reason for controlling condition

A supply of amino acids for carbohydrate synthesis

B supply of glucose waste product to be removed
C supply of oxygen for anaerobic respiration
D pH to be optimum for enzyme activity

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