393 - B SC Chemistry Semester VI KU
393 - B SC Chemistry Semester VI KU
393 - B SC Chemistry Semester VI KU
Credits: 2
Theory: 2 hours/week Marks - 40
UNIT-I
1. Importance of Natural Resources – Different Types Resources
2. Significance of Water Resources and their uses
3. Conservation of water and recycling of the water – Global distribution of water
4. Water shed programmes and their management
5. Storing the rain water in tanks and recharging ground water.
Unit-II
6. Rain water harvesting in rural areas (chekdam, trenches etc.,)
7. Over use of surface and ground water and control measures.
8. Aims, objectives and implementation of Mission Bhagiratha (Telangana Government Drinking
water programme )
9. Aims, objectives and implementation of Mission Kakatiya (Telangana Government minor
irrigation programme)
10. Issues and challenges in Water Resources Management
Page 2 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSC-1F)
SEMESTER – VI
Page 3 of 14
S6-O-2: Amino acids and proteins 05 Hrs
acids into acidic, basic and neutral amino acids with examples. Methods of synthesis: General
methods of synthesis of alpha amino acids (specific examples – Glycine, Alanine, valine and
Leucene) by following methods: a) From halogenated Carboxylic acid b)Malonic ester synthesis
c) strecker’s synthesis.Physical properties: Optical activity of naturally occurring amino acids: L
– configuration, irrespective of sign of rotation. Zwitter ion structure – salt like character,
solubility, melting points, amphoteric character, definition of isoelectric point. Chemical
properties: General reactions due to amino and carboxyl groups – Lactams from gamma and
delta amino acids by heating peptide bond (amide linkage). Structure and nomenclature of
peptides and proteins, peptide synthesis.
Unit-III (Physical Chemistry) 11 Hrs
S6-P-1: Thermodynamics –I 11 Hrs
A brief review of - Energy, work and heat units, mechanical equivalent of heat, definition of
system, surroundings. I law of thermodynamics statement- various forms mathematical
expression. Thermodynamic quantities- extensive properties and intensive properties, state
function, path functions energy as a state function, and exact differential. Work of expansion and
heat absorbed as path function. Expression for work of expansion, sign convention problems on I
law. Heat changes at constant pressure and heat changes at constant volume. Enthalpy. Heat
capacities at constant pressure and constant volume. Derivation Cp-Cv = R.
Isothermal adiabatic processes. Reversible and irreversible processes. Reversible change and
maximum work. Derivation of expression for maximum work for isothermal reversible process.
Problems. Internal energy of an ideal gas. Joules experiment and Joule-Thompson coefficient.
Adiabatic changes in ideal gas derivation of equation, PVγ = constant. P-V curves for isothermal
and adiabatic processes. Heat of a reaction at constant volume and at constant pressure, relation
between ΔH and ΔV. Variation of heat of reaction with temperature. Kirchhoff's equation and
problems. Limitations of I law and need for II law. Statement of II law of thermodynamics.
Cyclic process. Heat engine, Carnot’s theorem, Carnot’s cycle. Derivation of efficiency of heat
engine problems. Thermodynamic scale of temperature.
Unit-IV (General Chemistry) 12 Hrs
S6-G-1: Proton Magnetic Resonance Spectroscopy 04 Hrs
Principles of nuclear magnetic resonance, equivalent and non-equivalent protons, position of
signals. Chemical shift, NMR splitting of signals – spin-spin coupling, representation of proton
NMR spectrum – Integrations. 1H NMR spectrum of – ethyl bromide, acetaldehyde, 1,1,2-
tribromo ethane, ethyl acetate and acetophenone.
S6-G-2: Mass Spectrometry 04 Hrs
Electron Impact Mass: Basic principles, Nitrogen rule, types of ions: Molecular ion, fragment ion
and isotopic ions, representation of mass spectrum, types of peaks (molecular ion, fragment and
isotopic ion peaks). Determination of molecular weight Mass spectrum of ethyl chloride, ethyl
bromide and acetophenone.
S6-G-3: Thermodynamics- II 04 Hrs
Entropy: Definition from Carnot’s cycle. Entropy as a state function. Entropy as a measure of
disorder. Sign of entropy change for spontaneous and non- spontaneous processes & equilibrium
processes. Entropy changes in i). Reversible isothermal process, ii). Reversible adiabatic process,
iii). phase change, iv). reversible change of state of an ideal gas. Problems. Entropy of mixing
inert perfect gases. Free energy Gibb’s function (G) and Helmholtz’s function (A) as
thermodynamic quantities. Concept of maximum work and net work ΔG as criteria for
Page 4 of 14
spontaneity. Derivation of equation ΔG = ΔH – TΔS. significance of the equation. Gibbs
equations and the Maxwell relations. Variation of G with P, V and T.
References :
Unit- I
1. Basic Inorganic Chemistry by F.A.Cotton, G.Wilkinson and Paul.L. Gaus 3 rd edn Wiley
Publishers (2001).
2. Inorganic Chemistry Principles of structure and reactivity by James E.Huhey, E.A. Keiter and
R.L. Keiter 4th edn. (2006)
3. Metal Ions In Reaction mechanisms, K.Veera Reddy. Galgotia Publications Pvt Ltd(2004)
Unit- II
1. Text book of organic chemistry by Soni. Sultan Chand & Sons; Twenty Ninth edition (2012)
2. General Organic chemistry by Sachin Kumar Ghosh. New Age Publishers Pvt Ltd (2008)
3. Text book of organic chemistry by Morrison and Boyd. Person(2009)
4. Text book of organic chemistry by Graham Solomons. Wiley(2015)
5. Text book of organic chemistry by Bruice Yuranis Powla. 2nd Edition (2012)
Unit III
1. Principles of physical chemistry by Prutton and Marron. The Macmillan Company; 4th edition
(1970)
2. Text Book of Physical Chemistry by Soni and Dharmahara. Sulthan Chand & sons.(2011)
3. Text Book of Physical Chemistry by Puri, Sharmaand Pattania. chand and Co.(2017)
4. Physical Chemistry by Atkins & De Paula, 8th Edition, 2009
5. Text Book of Physical Chemistry by K. L. Kapoor. (2012)
6. Physical Chemistry through problems by S.K. Dogra. (2015)
7. Text Book of Physical Chemistry by R.P. Verma.
8. Elements of Physical Chemistry byLewis Glasstone. Macmillan (1966)
9. Thermodynamics by Rajaram, Vishal Publishing Co,(2013)
Unit IV
1. Basic Inorganic Chemistry by F.A.Cotton, G.Wilkinson and Paul.L. Gaus 3rd edn Wiley
Publishers (2001).
2. Organic Spectroscopy, William Kemp Palgrave Macmillan; 2nd Revised edition edition (1
February 1987)
3. Principles of physical chemistry by Prutton and Marron.( The Macmillan Company; 4th
edition (1970)
4. Text Book of Physical Chemistry by Soni and Dharmahara. Sulthan Chand & sons.(2011).
5. Text Book of Physical Chemistry by Puri,Sharmaand Pattania. chand and Co.(2017)
6. Thermodynamics by Rajaram. Vishal Publishing Co,(2013)
Page 5 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSC-1F)
SEMESTER – VI
LABORATORY COURSE
DSC-VI (P): CHEMISTRY-VII (Physical Chemistry-II)
(03 Hrs per week, 01 Credit) 45 Hrs
I. Distribution law
1. Determination of distribution coefficient of iodine between water and carbon
Tetrachloride/determination of molecular status and partition coefficient of benzoic acid in
Toluene and water.
2. Determination of distribution coefficient of acetic acid between n-butanol and water.
II. Electrochemistry
1. Determination of cell constant of conductivity cell.
2. Determination of dissociation constant (Ka) of acetic acid by conductivity measurements.
3. Determination of solubility and solubility product of BaSO4
III. Colorimetry
1. Verification of Beer’s - Lamberts law for KMnO4 and determine the concentration of given
solution.
IV. Adsorption
1. Adsorption of acetic acid on animal charcoal, verification of Freundlich isotherm.
V. Physical constants
1. Surface tension and viscosity of liquids.
Reference Books:
1. Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand &
Co.: New Delhi (2011).
2. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry, Universities
Press.
Page 6 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSE-1F)
SEMESTER – VI
ELECTIVE - A
Page 7 of 14
Drugs to treat metabolic disorders: Anti diabetic - Tolbutamide; Antiinflammatiory –
Ibuprofen; Cardiovascular- Glyceryl trinitrate; Antipyretic (paracetamol, aspirin) and Antacid-
Omeprazole.
Drugs acting on nervous system: Anesthetics-definition, Classification-local and general.
Volatile- Nitrous oxide, chloroform uses and disadvantages. Local anesthetics – benzocaine.
Unit- IV: Molecular Messengers and Health Promoting Drugs 11Hrs
S6-E-A-IV: Molecular Messengers: Introduction to hormones and neurotransmitters, Thyroid
hormones, Antithyroid drug-Carbimazol. Adrenaline: Adrenergic drugs- salbutamol, atenelol.
Serotonin: SSRIs- fluoxetine. Dopamine: Antiparkinson drug- Levodopa .
Health promoting drugs: Introduction, sources, Deficiency disorders and remedy of Vitamins
A,B, C, D, E, K and micronutrients – Na, K, Ca, Cu, Zn and I .
Reference books
1. G.L. Patrick: Introduction to Medicinal Chemistry, Oxford University Press, New York. 2013.
2. Thomas Nogrady, Medicinal Chemistry, Oxford Univ. Press, New York.2005.
3. David William and Thomas Lemke, Foye’s Principles of Medicinal Chemistry, Lippincott
Williams & Wilkins, 2008.
4. Ashutosh Kar Medicinal Chemistry, New Age International, 2005.
5. O.D.Tyagi & M.Yadav Synthetic Drugs by, Anmol Publications,1998.
6. Medicinal Chemistry by Alka L. Gupta, Pragati Prakashan.
7. G. L. David Krupadanam, D.Vijaya Prasad, K.Varaprasad Rao, K. L. N. Reddy, C. Sudhakar,
Drugs, Universities Press (India) Ltd. 2012.
Page 8 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSE-1F)
SEMESTER – VI
ELECTIVE - A
LABORATORY COURSE
DSE: CHEMISTRY LAB –VIII
(Qualitative analysis of Organic Compounds)
(02 Hrs per week, 01 Credit) 30 Hrs
Reference Books:
1. Vogel A I, Tatchell A R, Furnis B S, Hannaford A J & Smith P W G., Textbook of
Practical Organic Chemistry, Prentice-Hall, 5th edition, 1996
2. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry Orient-Longman, 1960.
3. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry, Universities
Press.
Page 9 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSE-1F)
SEMESTER – VI
ELECTIVE-B
Page 10 of 14
S6-E-B-IV: Petroleum and Petrochemical Industry: Composition of crude petroleum,
Refining and different types of petroleum products and their applications.
Fractional Distillation - Principle and process, Cracking -Thermal and catalytic cracking,
Reforming of Petroleum and non-petroleum fuels (LPG, CNG, LNG, bio-gas, fuels derived from
biomass), fuel from waste, synthetic fuels (gaseous and liquids), clean fuels. Petrochemicals:
Vinyl acetate, Propylene oxide, Isoprene and their uses.
Lubricants: Classification of lubricants, Properties and functions of lubricants (viscosity index,
point, pour point) and their determination. Lubricating oils (conducting and nonconducting)
Solid and semisolid lubricants, synthetic lubricants.
Reference books:
1. N. N. Melnikov, Chemistry of pesticides; Springer-Verlag- Technology & Engineering (2012).
2. Thomas A. Unger Pesticide Synthesis Handbook; Elsevier, (2000).
3. R. Cremlyn Pesticides; John Wiley, 1980.
4. A. K. Kolay Manures and Fetrtilisers; Published by Atlantic (2007).
5. Stocchi, E. Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK (1990).
6. Jain, P.C. & Jain, M. Engineering Chemistry Dhanpat Rai & Sons, Delhi.
7. Sharma, B.K. & Gaur, H. Industrial Chemistry, Goel Publishing House, Meerut (1996).
Page 11 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSC-1F)
SEMESTER – VI
Elective-B
LABORATORY COURSE
DSE: CHEMISTRY LAB –VIII
(Synthesis of Drugs & Organic Compounds)
(02 Hrs per week, 01 Credit) 30 Hrs
1. Preparation of Aspirin
2. Preparation of Paracetamol
3. Preparation of Acetanilide
4. Preparation of Barbutiric Acid
5. Preparation of Antipyrine
Reference Books:
Page 12 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSC-1F)
SEMESTER – VI
Elective-C
CHEMISTRY PAPER-VIII
DSE: GREEN CHEMISTRY
(03 Hrs per week, 03 Credits) 45 Hrs
UNIT-I 11Hrs
S6-E-C-1: Introduction of Green Chemistry
Introduction- Definition of green Chemistry, need of green chemistry, basic principles of green
chemistry. Green synthesis- Evalution of the type of the reaction i) Rearrangements (100% atom
economic), ii) Addition reaction (100% atom economic). Organic reactions by Sonication
method: apparatus required examples of sonochemical reactions (Heck, Hundsdiecker and Wittig
reactions).
UNIT-II 11 Hrs
S6-E-C-2: Selection of Solvent
i) Aqueous phase reactions ii) Reactions in ionic liquids, Heckreaction, Suzuki reactions,
epoxidation. iii) Solid supported synthesis
Super critical CO2: Preparation, properties and applications, (decaffeination, dry cleaning)
UNIT-III 11Hrs
S6-E-C-3: Microwave and Ultrasound assisted green synthesis
Apparatus required, examples of MAOS (synthesis of fused Anthraquinone, Leukart reductive
amination of ketones) - Advantages and disadvantages of MAOS. Aldol condensation-
Cannizzaro reaction-Diels-Alder reactions-Strecker's synthesis
UNIT-IV 12 Hrs
S6-E-C-4: Examples of green synthesis / reactions and some real world cases:
1. Green synthesis of the following compounds: adipic acid , catechol , disodium imino di
acetate (alternative Strecker’s synthesis)
2. Microwave assisted reaction in water – Hoffmann elimination – methyl benzoate to benzoic
acid – oxidation of toluene and alcohols – microwave assisted reactions in organic solvents.
Diels-Alder reactions and decarboxylation reaction.
3. Ultrasound assisted reactions – sonochemical Simmons –Smith reaction (ultrasonic alternative
to iodine)
Reference books
1. Green Chemistry Theory and Practice. P.T.Anatas and J.C. Warner
2. Green Chemistry V.K. Ahluwalia., Narosa, New Delhi.
3. Real world cases in Green Chemistry M.C. Cann and M.E. Connelly
4. Green Chemistry: Introductory Text M.Lancaster: Royal Society of Chemistry (London)
5. Green Chemistry: Introductory Text, M.Lancaster
6. Principles and practice of heterogeneous catalysis, Thomas J.M.,Thomas M.J., John Wiley
7. Green Chemistry: Environmental friendly alternatives R S Sanghli and M.M Srivastava,
Narosa Publications.
Page 13 of 14
KAKATIYA UNIVERSITY
U.G. CHEMISTERY (Under CBCS)
B.Sc. Final Year (DSC-1F)
SEMESTER – VI
Elective-C
LABORATORY COURSE
DSE: CHEMISTRY LAB –VIII (Preparation of Organic Compounds by Green Methods)
(02 Hrs per week, 01 Credit) 30 Hrs
Reference Books:
Page 14 of 14