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    Drug Study Clozapine

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    Krizzia Foster
    Clozapine is an atypical antipsychotic used to treat schizophrenia. It works by interfering with dopamine and serotonin receptor sites to diminish schizophrenic behavior. Common side effects include sedation, dizziness, fast heartbeat, constipation, and increased salivation. Rare but serious side effects include seizures, respiratory depression, coma, and blood dyscrasias like agranulocytosis. Patients taking clozapine require regular monitoring of vital signs and blood work. Abrupt discontinuation should be avoided.

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    Drug Study Clozapine

    Uploaded by

    Krizzia Foster
    24 views2 pages
    Clozapine is an atypical antipsychotic used to treat schizophrenia. It works by interfering with dopamine and serotonin receptor sites to diminish schizophrenic behavior. Common side effects include sedation, dizziness, fast heartbeat, constipation, and increased salivation. Rare but serious side effects include seizures, respiratory depression, coma, and blood dyscrasias like agranulocytosis. Patients taking clozapine require regular monitoring of vital signs and blood work. Abrupt discontinuation should be avoided.

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    Drug study Clozapine

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    Clozapine is an atypical antipsychotic used to treat schizophrenia. It works by interfering with dopamine and serotonin receptor sites to diminish schizophrenic behavior. Common side effects include sedation, dizziness, fast heartbeat, constipation, and increased salivation. Rare but serious side effects include seizures, respiratory depression, coma, and blood dyscrasias like agranulocytosis. Patients taking clozapine require regular monitoring of vital signs and blood work. Abrupt discontinuation should be avoided.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    24 views2 pages

    Drug Study Clozapine

    Uploaded by

    Krizzia Foster
    Clozapine is an atypical antipsychotic used to treat schizophrenia. It works by interfering with dopamine and serotonin receptor sites to diminish schizophrenic behavior. Common side effects include sedation, dizziness, fast heartbeat, constipation, and increased salivation. Rare but serious side effects include seizures, respiratory depression, coma, and blood dyscrasias like agranulocytosis. Patients taking clozapine require regular monitoring of vital signs and blood work. Abrupt discontinuation should be avoided.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Drug study Clozapine

    Generic: Dosage: 25 mg Interferes with binding Schizophrenia Seizures (occasionally) Do not stop the 1. Assess behavior, appearance,
    Clozapine of dopamine and Overdose produces medications abruptly emotional status, response to
    serotonin receptor sites, CNS depression environment, speech pattern,
    Route: Oral thereby diminishing (sedation, delirium, Use cautiously thought content.
    schizophrenic coma), respiratory among smokers 2. Monitor BP for
    Brand: Syclop Frequency: BID behavior. depression, hypertension/hypotension.
    hypersalivation. Use cautiously 3. Assess pulse for tachycardia
    Blood dyscrasias, among patients with (common side effect).
    Timing: 8, 6 particularly CV or 4. Monitor CBC for blood
    agranulocytosis, mild cerebrovascular dyscrasias.
    leukopenia, may occur. disease or conditions 5. Supervise suicidal-risk pt
    Classification Contraindications Side Effects predisposing to closely during early therapy
    Functional: ● Hypersensitivity ● Blurred vision hypotension, history (as depression lessens,
    Second- to clozapine. ● Dizziness of or risk factors for energy level improves,
    generation ● History of ● Fast heartbeat seizure, risk or increasing suicide potential).
    (atypical) clozapine- ● Shaking of the history of QT 6. Assess for therapeutic
    antipsychotic induced hands or feet prolongation, DM, response (interest in
    agranulocytosis ● Constipation BPH, urinary surroundings, improvement
    or severe ● Increased salivation retention, xerostomia, in self- care, increased ability
    granulocytope- ● Anxiety decreased to concentrate, relaxed facial
    Chemical: nia. ● Dry mouth gastrointestinal expression)
    C18H19ClN4 ● Weight gain motility, visual 7.
    ● Acid or sour problems.
    stomach
    ● Muscle pain PATIENT/FAMILY
    ● Sore throat TEACHING
    ● Do not abruptly
    discontinue long-
    term drug
    therapy.
    ● Avoid tasks that
    require alertness,
    motor skills until
    response to drug
    is established.
    ● Drowsiness
    generally
    subsides during
    continued
    therapy.
    ● Avoid alcohol,
    caffeine.
    ● Report fever, sore
    throat, flu-like
    symptoms.

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