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    Sketchy Opioids

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    Sandy Mae
    Opioid analgesics, Opioid antitussives, Opioid antidiarrheal, Methadone, Buprenorphine, Naloxone, Naltrexone

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    © All Rights Reserved
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    Sketchy Opioids

    Uploaded by

    Sandy Mae
    423 views1 page
    Opioid analgesics, Opioid antitussives, Opioid antidiarrheal, Methadone, Buprenorphine, Naloxone, Naltrexone

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    © © All Rights Reserved

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    Opioid analgesics, Opioid antitussives, Opioid antidiarrheal, Methadone, Buprenorphine, Naloxone, Naltrexone

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    423 views1 page

    Sketchy Opioids

    Uploaded by

    Sandy Mae
    Opioid analgesics, Opioid antitussives, Opioid antidiarrheal, Methadone, Buprenorphine, Naloxone, Naltrexone

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    Opioid analgesics, Opioid antitussives, Opioid antidiarrheal,

    Methadone, Buprenorphine, Naloxone, Naltrexone


    Saturday, January 29, 2022 6:43 PM

    Partial Opioid Agonists


    • Drugs
    ○ Buprenorphine Open K+ channels & close Tramadol
    ○ Nalbuphine presynaptic VG Ca2+ channels • Inhibit NE & 5-HT
    ○ Butorphanol • Chronic Pain
    • Can induce WD

    WD Effects "Moist":
    • Rhinorrhea
    • Lacrimation
    • Hyperthermia Chronic Pain
    • n/v/d Fantasy: Fentanyl : also post op
    • Body aches More Fun: Morphine
    • Anxiety

    Neonatal Abstinence
    Syndrome
    Cough
    dextromethorphan: Block NMDA also
    Codeine
    DONE timer: Methadone
    • Long acting opioid
    to help WD
    • Long 1/2 life

    Blueprint: Buprenorphine
    • Long acting partial
    opioid agonist to
    help WD
    • Long 1/2 life

    • Respiratory Depression
    Naltrexone Naloxone • Sedation Receptors in GI tract, constipation
    • Opioid Antagonist • Opioid Antagonist • Miosis Loperamide, Diphenoxylate = Antidiarrheals
    • Helps abstinence in heroin • To reverse opioid • Constipation
    addicts toxicity • Biliary Colic
    • Helps reduce alcohol & • Tolerance ( not to constipation
    nicotine addiction or miosis)
    • Hyperalgesia (chronic use)

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