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    Ceftriaxone Med Card

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    Anja de Vries
    Ceftriaxone is a 3rd generation cephalosporin antibiotic administered intravenously or intramuscularly. It works bactericidally by weakening the bacterial cell wall. Onset of action is within 5 minutes via IV or 1 hour via IM. Common side effects include pain or tenderness at the injection site, diarrhea, and allergic reactions. The nurse should assess for drug allergies and underlying medical conditions prior to administration. After administering, the nurse monitors for signs of allergic reaction and assesses the effectiveness based on urine output and symptom resolution. Ceftriaxone should not be mixed or administered with calcium-containing solutions.

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    Ceftriaxone Med Card

    Uploaded by

    Anja de Vries
    17 views2 pages
    Ceftriaxone is a 3rd generation cephalosporin antibiotic administered intravenously or intramuscularly. It works bactericidally by weakening the bacterial cell wall. Onset of action is within 5 minutes via IV or 1 hour via IM. Common side effects include pain or tenderness at the injection site, diarrhea, and allergic reactions. The nurse should assess for drug allergies and underlying medical conditions prior to administration. After administering, the nurse monitors for signs of allergic reaction and assesses the effectiveness based on urine output and symptom resolution. Ceftriaxone should not be mixed or administered with calcium-containing solutions.

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    Ceftriaxone is a 3rd generation cephalosporin antibiotic administered intravenously or intramuscularly. It works bactericidally by weakening the bacterial cell wall. Onset of action is within 5 minutes via IV or 1 hour via IM. Common side effects include pain or tenderness at the injection site, diarrhea, and allergic reactions. The nurse should assess for drug allergies and underlying medical conditions prior to administration. After administering, the nurse monitors for signs of allergic reaction and assesses the effectiveness based on urine output and symptom resolution. Ceftriaxone should not be mixed or administered with calcium-containing solutions.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    17 views2 pages

    Ceftriaxone Med Card

    Uploaded by

    Anja de Vries
    Ceftriaxone is a 3rd generation cephalosporin antibiotic administered intravenously or intramuscularly. It works bactericidally by weakening the bacterial cell wall. Onset of action is within 5 minutes via IV or 1 hour via IM. Common side effects include pain or tenderness at the injection site, diarrhea, and allergic reactions. The nurse should assess for drug allergies and underlying medical conditions prior to administration. After administering, the nurse monitors for signs of allergic reaction and assesses the effectiveness based on urine output and symptom resolution. Ceftriaxone should not be mixed or administered with calcium-containing solutions.

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    Generic Name: Ceftriaxone Trade name: Rocephin

    Pharmacologic Class: Antibiotic, 3rd generation Usual dose: 1-2g/50mL IV (or IM) or divided q12hrs, max: 4g
    Cephalosporin

    Action (What does it do? How long does it take to work?): Uses for this medication:
    Bactericidal - weakens bacterial cell wall, causing cell death. - Infections  gonorrhea, pelvic inflammatory disease,
    Active against many gram-positive pathogens. meningitis, pneumonia, septicemia, otitis media
    - Perioperative prophylaxis
    Onset: 5 minutes (IV), 1 hour (IM) Duration: 5-8 hrs
    Common side effects:
    - pain/tenderness/hardness/warmth @ injection site
    - pale skin, weakness, SOB when exercising
    - diarrhea (incl. C-diff associated diarrhea)

    Serious complications
    - rash, bloody/watery stools, cramps, N/V
    - chest pain, heartburn, painful urination, decreased urination, foul smelling urine, edema in legs and feet,
    peeling/blistering/shedding skin
    - seizures

    Clinical Judgment
    Pre-administration assessment: What should the nurse assess before administering the medication?
    - Hx of hypersensitivity reactions to cephalosporins/penicillin (beta-lactam Abx) or other drug allergies
    - Bowel functions – N/V/D
    - Hx of colitis, hyperbilirubinemia, gallbladder disease, pancreatitis, renal/liver disease, seizure disorders
    - Dx of anemia or coagulation disorders – PTT alterations
    - Lab tests: CBC, renal and hepatic function, electrolytes
    - Culture & sensitivity
    - Vitals (RR, pulse, BP, temp)
    - IV site – redness, edema, pain, temperature, infection, leakage, embolism

    How will the nurse know if it is appropriate to administer?


    - No N/V/D, no Hx of hypersensitivity to cephalosporins/penicillin, no complications at IV site, no GI disease, anemia,
    coagulation disorders

    Post- administration assessment: What should the nurse assess after administering the medication? How will you know if the
    medication is effective?
    - Monitor S&S of allergic reactions and anaphylaxis: pulmonary symptoms (tightness in throat and chest, wheezing, cough,
    dyspnea) or skin reactions (rash, pruritis, urticaria)
    - Monitor for hypersensitivity reaction, urine output

    Nursing considerations:
    - Precipitation of ceftriaxone-calcium can also occur when Rocephin is mixed with calcium-containing solutions in the
    same IV administration line  DO NOT admin Ca-containing IV solutions simultaneously (e.g. parenteral nutrition)
    - Drug-drug interactions: aminoglycosides – increased risk for nephrotoxicity, oral anticoagulants – increased bleeding
    - Avoid alcohol for 72 hours after discontinuation of the drug to prevent disulfiram-like reaction (e.g. flushing, throbbing
    headache, N/V, chest pain, palpitations, dyspnea, syncope, vertigo, convulsions)

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