Thoma 2015
Thoma 2015
Thoma 2015
History of CBT
behavior from the simplest of habits all the way up to the acquisition of
language (Skinner, 1957). Skinner’s operant learning methods are still
directly applied to this day in such paradigms as token economies on
inpatient units as well as behavioral interventions with children, such
as “time outs.”
One of the first researchers to apply behavioristic principles to clini-
cal applications was Mary Cover Jones, Watson’s assistant in the Little
Albert experiment. She reasoned that if conditioning could be used to
induce a phobia, perhaps it could be used to undo a phobia as well
(Jones, 1924). For example, she reduced fear in a three-year-old boy
who was afraid of fuzzy white objects by gradually bringing a rabbit
in a cage closer and closer to the boy while he ate so that he eventually
was able to touch it. Other early clinical applications include Pavlovian
extinguishing of bedwetting (Mowrer & Mowrer, 1938) and the devel-
opment of progressive relaxation techniques (Jacobson, 1929), which
were applied to a wide variety of physical and mental conditions, in-
cluding hypertension, insomnia, and phobias.
While there are many behavior therapies that are heralded as the
forerunners for current practices (such as Wolpe’s systematic desensiti-
zation or Beck’s cognitive therapy, described below), one of the first be-
havior therapies widely administered to clients was assertion training.
Developed by Andrew Salter, assertion training was designed to assist
clients to overcome their inhibitions, which were widely considered the
etiological basis for neurosis (Salter, 1949). Salter’s work was highly in-
fluential, even if little recognized outside behavior therapy circles. His
work in developing a behavior therapy was the basis for more highly
developed assertiveness training programs, including the widely used
client-oriented book Your Perfect Right (Alberti & Emmons, 2008). As-
sertion training remains a critical component of many CBT protocols.
Like many of the early developers of CBT, Joseph Wolpe was a psy-
chiatrist originally trained as a psychoanalyst. Wolpe then became in-
terested in finding ways to apply behavioristic principles to humans
(Glass & Arnkoff, 1992). Working in his native country of South Africa,
he began with de-conditioning experiments on cats and then applied
his findings to humans, developing one of the earliest behavior thera-
pies known as systematic desensitization (Wolpe, 1958). This approach,
using what Wolpe called reciprocal inhibition, centered on exposure to
feared stimuli through use of imaginal imagery, which would then be
alternated with relaxing imagery. The theory held that the relaxation
response would become coupled with the target imagery in place of
the fear response, under the belief that incompatible physiological re-
sponses would allow for the transfer of new associations. Systematic
desensitization was used to treat phobias, social anxiety, generalized
CONTEMPORARY COGNITIVE BEHAVIOR THERAPY 427
There are more RCTs of CBT for depression than there are for any oth-
er psychotherapy for any other disorder, making it the most replicated
test of psychotherapy in the literature. Thoma and colleagues (2012)
found 120 trials of CBT for depression as of 2010, a number which has
since grown. This included comparisons of CBT to a variety of control
conditions, including a wait list, treatment-as-usual (TAU), other psy-
chotherapies, medication, and the combination of CBT and medication.
Most of these trials focused on major depressive disorder (MDD) and
over half used the Beckian model. In comparison to a wait list control,
CBT has shown large effects, with Cohen’s d = 0.90 (Thoma et al., 2012).1
This demonstrates that CBT does better than doing nothing. In compar-
ison to TAU, medium effects were found, with d = 0.40. However, this
finding is ambiguous, as Wampold et al. (2011) demonstrated that TAU
can consist of a wide array of control conditions that range from very
inactive to bona fide treatment. In comparison to medication, no differ-
ence was found, with an effect size close to zero at d = 0.10. This sug-
gests that on average, the effects of CBT for depression are comparable
to that of antidepressant medication. In comparison to other forms of
psychotherapy, likewise the effect was nonsignificant and close to zero,
with d = 0.05. In sub-analyses, in which comparisons between CBT and
BT were removed, the results were the same. Alternatively, a compari-
1. By convention, effect sizes of d = 0.20, 0.50, and 0.80 are considered to be small,
medium, and large, respectively (Cohen, 1988).
434 THOMA ET AL.
son between CBT and CBT with medication, the combined treatment
had larger effects, showing additive effects of the two treatments.
Taken together, these findings indicate that CBT is decidedly better
than nothing but perhaps no better and no worse than medication or
other psychotherapies for treating a major depressive episode. Com-
bining CBT with medication appears to have beneficial additive effects.
Interestingly, Thoma et al. (2012) found that the quality of the method-
ology of the RCTs was inversely related to outcome. This is to say, the
better the trial, the worse the outcome for CBT. Additionally, there was
evidence of publication bias. This means that the aggregated results
may be somewhat inflated due to trials with small sample sizes and
poor results going unpublished.
Trials of group versus individually based CBT have yielded similar
results, with some evidence favoring the efficacy of individual treat-
ment (Cuijpers, van Straten, & Warmerdam, 2008). Findings for CBT
for chronic depression and dysthymia have been somewhat less strong
than for MDD. Cuijpers et al. (2010) found only a medium effect for CBT
versus a control condition (which could have been either a wait list or
TAU), with d = 0.43. And unlike CBT for MDD, medication was found
to be superior, by a medium effect of d = 0.50. Combined treatment
showed a small to medium advantage over either treatment alone.
In examining the mechanisms of change in CBT for depression,
some authors have pointed toward evidence supporting the effects of
theoretically relevant change processes (e.g., Garrett, Ingram, Rand, &
Sawalani, 2007) while others have questioned this evidence (e.g., Ahn
& Wampold, 2001). Much of this dispute rests on the debate between
the relative importance of common factors versus specific techniques.
The theory proposed by Beck indicates that it is changes in cogni-
tions, such as negative beliefs about the self, the world, and the future,
which produce changes in emotional symptoms and lead to the alle-
viation of depression (Beck, 1979). This would imply that changes in
cognitions should precede changes in symptoms. A variety of studies
have found change in dysfunctional attitudes and beliefs to be correlat-
ed with reduced depressive symptoms at post-treatment (Garrett et al.,
2007), but this does not speak to the problem of temporal sequencing.
Findings centering on observations of within-session changes in cogni-
tions leading to within-session changes in mood have been mixed. Per-
sons and Burns (1985, 1986) and Teasdale and Fennell (1982) found that
modification of negative thoughts was correlated with improvements
in mood. However, Safran, Vallis, Segal, and Shaw (1987) did not find
this relationship.
Yet it remains possible that there is a necessary incubation period
after changes in cognitions before symptom relief occurs. To investigate
CONTEMPORARY COGNITIVE BEHAVIOR THERAPY 435
Anxiety Disorders
ditions). However, the concerns raised about the procedure have not
been associated with any poor outcome, and so dissemination is pri-
marily a matter of good supervision and training for uninitiated thera-
pists (Richard & Gloster, 2006). To remind readers, exposure involves
a direct confrontation with the feared objects of the client, through in
vivo practice with the therapist, in guided imagery, and in between ses-
sion homework assignments (see Abramowitz, Deacon, & Whiteside,
2010, for detailed coverage). The therapeutic mechanism of exposure
is habituation to the feared stimuli. While many clinicians express con-
cern over exposure, it may be more accurate to say that exposure re-
quires considerable care and training for proper implementation, and
that when done properly it is a highly effective method for alleviating
anxiety. Indeed, recent investigations have shown that as fear of caus-
ing client harm increases, efficacy of exposure interventions decreases
(Farrell, Deacon, Kemp, Dixon, & Sy, 2013). Accordingly, a potential
harmful side effect of exposure is not conducting it at all, but conduct-
ing it at a level below the necessary threshold of intensity. This means
that hesitant clinicians may require additional supervision to overcome
their concerns over potential harm, as well as their personal discomfort
whereby they may view exposure as incompatible with compassion
(McKay & Ojserkis, 2014).
While exposure may give pause to PDT practitioners, there is a new
conceptualization of the approach that may put clinicians at greater
ease. Specifically, it has been acknowledged that most clinicians do not
merely present feared stimuli and wait for habituation. Instead, clini-
cians engage in a wide range of other therapeutic interventions de-
signed expressly for encouraging clients to practice exposure and to
facilitate a beneficial response. This is the inhibitory learning model
mentioned earlier (i.e., Craske et al., 2014). This approach emphasizes
new learning, such as distress tolerance or altered expectations for out-
come following exposure rather than habituation per se. It also perhaps
better represents the everyday practice of exposure, whereby interper-
sonal processes play a significant role in how clinicians engage clients
in exposure. For example, one principle of the inhibitory learning mod-
el emphasizes expectancy violation. Clinicians may introduce humor,
which is contrary to fear experience, when conducting exposure. An-
other aspect is occasional reinforcement during the course of exposure.
This again is not consistent with the original conceptualization of expo-
sure, but it does serve an important framework for understanding the
interpersonal relationship between client and therapist in completing
exposure exercises.
CONTEMPORARY COGNITIVE BEHAVIOR THERAPY 439
Various forms of CBT have been applied and investigated for the
treatment of personality disorders (PDs). The first set of models of CBT
consist of various combinations of traditional CT and BT. The other two
models that have been investigated were specifically developed to ad-
dress PDs, and borderline personality disorder (BPD) in particular. The
first of these is dialectical behavior therapy (DBT; Linehan, 1993) and
the second is schema therapy (ST; Young, Klosko, & Weishaar, 2003).
Relatively few RCTs have been conducted of traditional CBT for PDs.
This may be because many clinicians and researchers would not as-
sume that short-term CT or BT would be expected to show efficacy in
patients defined by the chronicity and pervasiveness of their symp-
toms. Several trials have applied CBT to avoidant personality disorder
(AvPD), which can be seen as a more generalized form of social phobia,
and therefore a reasonable target for CBT. Alden (1989) found CBT to be
more effective in treating AvPD than a wait list control. Emmelkamp et
al. (2006) found CBT to be more effective than WL as well as psychody-
namic therapy (PDT). The latter was not significantly better than WL.
In testing CBT and PDT on cluster C PDs, Svartberg, Stiles, and Seltzer
(2004) found patients in both treatments improved, with no significant
difference between the two groups. Differences between trials may be
due to sampling differences and/or differences in treatment implemen-
tation.
Linehan’s DBT has been tested on PDs more than any other man-
ualized psychotherapy. Linehan moved the field of CBT forward by
targeting one of the most difficult and intractable disorders, BPD, and
manualizing a year-long treatment for it, and thus moving CBT beyond
the typical 12–20 session format. Further, rigorous training programs
have been developed, helping DBT to become one the most widely dis-
seminated manualized therapies. Kliem, Kröger, and Kosfelder (2010)
used a contemporary statistical method for including multiple outcome
measures and found a medium effect size favoring DBT over TAU, cli-
ent-centered therapy, and treatment by community experts. However,
when compared with active treatments that were designed for BPD,
namely Kernberg’s transference-focused psychotherapy (TFP; Clarkin,
Levy, Lenzenweger, & Kernberg, 2007) and a BPD-specific, manualized
PDT (McMain et al., 2009), DBT showed a disadvantage by a small ef-
fect. Across the trials studied, gains in DBT decreased, on average, by a
small effect upon measurement at long-term follow-up.
Given the widespread dissemination and clinical notoriety of DBT,
it may be somewhat surprising that the approach has only a medium
effect over TAU and potentially even a small disadvantage against oth-
440 THOMA ET AL.
Substance Abuse
Eating Disorders
Schizophrenia
Chronic Pain
Insomnia
Depression
There has been extensive research into the efficacy of CBT for depres-
sion in children. Interestingly, unlike other conditions, CBT has shown
mixed results in alleviating depression in younger populations. There
are several models of intervention that have been developed for chil-
dren with depression, with some emphasizing increasing behaviors in
a manner akin to behavioral activation for adults along with specifi-
cally targeting dysfunctional cognitions that promote depressed mood
(i.e., Lewinsohn, Clarke, Hops, & Andrews, 1990). Another emphasizes
primarily cognitions in a manner similar to the approach described by
Beck, Rush, Shaw, and Emery (1979) tailored for children. In one large
multi-site trial using a protocol that was a flexible adaptation of the
Lewinsohn et al. model, children treated with a combination of CBT
with fluoxetine were the only ones to significantly improve (compared
to those treated with either intervention alone; The Treatment on Ado-
lescent Depression Study; TADS, 2007). In a more recent review of the
available evidence, it was concluded that CBT did not yet have ade-
quate empirical support for it to be declared an evidence-based treat-
ment for childhood depression (Nel, 2014). This disappointing outcome
suggests that far more work needs to be done in order to alleviate child-
hood depression. One area not fully developed is determining methods
for best involving parents and caregivers in the childhood depression
treatment, as well as other systematic methods for integrating treat-
ment with medication-based therapies (Curry & Becker, 2009).
CONTEMPORARY COGNITIVE BEHAVIOR THERAPY 447
Anxiety
Future Directions
While much development and research has been done on CBT, there
clearly remains more work to be done. Some of this rests on a shift in
emphasis in the kind of research to be completed. Randomized con-
trolled trials are the gold standard in intervention research, however
RCTs have some limitations, particularly when applied to psychother-
apy research (see Wachtel, 2010, for a critique). While RCTs can tell us
that a given psychotherapy works better than a control condition, RCTs
do not tell us what about the therapy caused the change (Borkovec &
Castonguay, 1998). Thus, process-outcome research is needed to deter-
mine the active ingredients. While some progress has been made, this
remains a priority for CBT researchers, as it is also for psychotherapy
researchers of all stripes (Barber, 2009).
Better understanding the mechanisms at play in CBT will help bet-
ter understand how to further enhance CBT treatments in several re-
gards. For one, it will clarify the relationship between techniques and
so-called common factors, such as the benefits of a therapeutic relation-
ship. In our view, all therapist behaviors can ultimately be regarded
as specific effects that a therapist can deliver more or less of, or de-
liver more or less skillfully. We strongly agree with those who argue
for the importance of the therapeutic relationship, and further, we view
it as a manipulable variable. Thus, better understanding mechanisms
will help us understand therapist effects better—that is, what makes
more effective CBT therapists thusly more effective. Is it that they are
better at forming and maintaining the relationship? More nuanced in
their administration of techniques? Or a complex combination? This is
also a priority that will feed into how we train the next generation of
therapists and disseminate the findings of CBT. Lastly, better under-
standing mechanisms may help us fundamentally modify treatments
to further improve outcomes. No CBT protocols we are aware of have
consistently shown a 100% remission rate. Our survey of the literature
has shown us that remission rates vary widely, such as less than 30%
for the short-term treatment of complex PTSD in persons who have
experienced childhood sexual abuse (Cloitre et al., 2010) and up to 80%
recovery rate in a two-year course of schema therapy for personality
disorders (Bamelis et al., 2014). One question would be as to whether
CONTEMPORARY COGNITIVE BEHAVIOR THERAPY 451
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Nathan Thoma
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