Non-Mendelian Notes Edited
Non-Mendelian Notes Edited
Non-Mendelian Notes Edited
Mendelian inheritance patterns involve genes that directly influence the outcome of an organism’s traits and
obey Mendel’s laws.
Most genes in eukaryotic species follow a Mendelian pattern of inheritance. However, there are many that do
not.
Non-Mendelian Inheritance is a general term that refers to any pattern of inheritance in which traits do not
segregate in accordance with Mendel’s laws. These laws describe the inheritance of traits linked to
single genes on chromosomes in the nucleus.
1. Co-dominance
When the alleles for a particular trait are co-dominant, they are both expressed equally rather than a dominant
allele taking complete control over a recessive allele.
This means that when an organism has two different alleles (i.e., is a heterozygote), it will express both at the
same time.
Example
Sometimes in a heterozygote dominant allele does not completely mask the phenotypic expression of the
recessive allele and there occurs an intermediate phenotype in the heterozygote. This is called incomplete
dominance.
With co-dominant alleles, both traits are expressed at the same time. With incomplete dominance, the same
thing occur but the traits are blended together rather than occurring in discrete patches.
It thus refers to the condition in heterozygotes where the phenotype is intermediate between the two
homozygotes.
Example:
In some plants the cross of red and white produces pink-flowered progeny
(Four-o’clock plants (Mirabilis jalapa) or snapdragons (Antirrhinum majus).
Davenport (1913) in Jamaica found that two pairs of genes, A-a and B-b cause the difference in skin pigmentation
between negro and caucasian people. These genes were found to affect the character in additive fashion.
Thus, a true negro has four dominant genes, AABB, and a white has four recessive genes aabb. The F1 offspring of
mating of aabb with AABB, are all AaBb and have an intermediate skin colour termed mulatto. A mating of two such
mulattoes produces a wide variety of skin colour in the offspring, ranging from skins as dark as the original negro parent
to as white as the original white parent.
4. Multiple Alleles
Mendel studied just two alleles of his pea genes, but real populations often have multiple alleles of a given gene.
There are three common alleles for the gene that controls this characteristic. The alleles I A and IB are dominant over i. A
person who is homozygous recessive ii has type O blood. Homozygous dominant IAIA or heterozygous dominant IA i have
type A blood, and homozygous dominant IBIB or heterozygous dominant IB i have type B blood. IAIB people have type AB
blood, because the A and B alleles are co-dominant. Type A and type B parents can have a type AB child. Type A and type
B parents can also have a child with Type O blood, if they are both heterozygous (I B i, IA i).
Type O blood: ii