Drug Study Rifampicin

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Ateneo de Zamboanga University

College of Nursing
Level II
School Year 2021-2022
A. Drug Study
Drug Mechanism of action/Side Indication/ Nursing Responsibilities
effects Contraindication
Brand name: Rifadin Mechanism of Action: Indication: • Follow 14 rights of
Generic name: Rifampicin Rifampin acts via the Rifampin is indicated for medications
Classification: inhibition of DNA- the treatment of can turn body fluids red
Antitubercular Agents dependent RNA tuberculosis and • may cause diarrhea,
Route: PO polymerase, leading to a tuberculosis-related nausea, vomiting,
Dosage: 200mg suppression of RNA mycobacterial infections. In confusion
Frequency: OD, AC synthesis and cell death. combination with • assess lung sounds and
Side Effects: pyrazinamide and isoniazid, sputum characteristics
 heartburn it is used in the initial phase • evaluate renal and liver
 abdominal pain of the short-course function tests
 loss of appetite treatment of pulmonary • instruct patient not to
 nausea tuberculosis. skip or double dose
 vomiting Contraindication: • must complete entire
 fever  diabetes. dose (6-12 month
 porphyria. therapy)
 hemolytic uremic
syndrome, a
condition that
affects the kidney
and the blood.
 decreased blood-
clotting from low
vitamin K.
 alcoholism.
 thrombotic
thrombocytopenic
purpura, a type of
blood disorder.
 liver problems.
 abnormal liver
function tests.

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